A practical synthesis of [(1 S,3 S)-3-aminocyclohexyl]methanol and 2-[(1 S,3 S)-3-aminocyclohexyl]propan-2-ol, useful intermediates for the preparation of novel m PGES-1 inhibitors

Synlett

Volumn , Issue 20, 2011, Pages 2959-2962

  Walker, Daniel P ^a   Heasley, Steven E ^a   MacInnes, Allison ^a   Anjeh, Tizah ^a   Lu, Hwang Fun ^a   Fobian, Yvette M ^a   Collins, Joe T ^a   Vazquez, Michael L ^a   Mao, Michael K ^a  

^a PFIZER INC   (United States)

Author keywords

anti inflammatory agents; carbocycles; chiral resolution; heterocycles; rearrangement

Indexed keywords

(3 AMINOCYCLOHEXYL)METHANOL; 2 (3 AMINOCYCLOHEXYL)PROPAN 2 OL; AMINOALCOHOL; PROSTAGLANDIN SYNTHASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; CHIRAL CHROMATOGRAPHY; DRUG STRUCTURE; DRUG SYNTHESIS; ENANTIOMER; RACEMIZATION;

EID: 82955198446     PISSN: 09365214     EISSN: 14372096     Source Type: Journal    
DOI: 10.1055/s-0031-1289884     Document Type: Article

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