Impact of body weight and extreme obesity on the presentation, treatment, and in-hospital outcomes of 50,149 patients with ST-segment elevation myocardial infarction: Results from the NCDR (National Cardiovascular Data Registry)

Journal of the American College of Cardiology

Volumn 58, Issue 25, 2011, Pages 2642-2650

  Das, Sandeep R ^a   Alexander, Karen P ^b   Chen, Anita Y ^b   Powell Wiley, Tiffany M ^a   Diercks, Deborah B ^c   Peterson, Eric D ^b   Roe, Matthew T ^b   De Lemos, James A ^a  

^a UNIVERSITY OF TEXAS AT DALLAS   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

extreme obesity; obesity; outcomes; quality of care; STEMI

Indexed keywords

ACETYLSALICYLIC ACID; ALDOSTERONE ANTAGONIST; ANGIOTENSIN RECEPTOR ANTAGONIST; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CLOPIDOGREL; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; FIBRINOGEN RECEPTOR ANTAGONIST; FIBRINOLYTIC AGENT; HEPARIN; HIRULOG; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LOW MOLECULAR WEIGHT HEPARIN;

ADULT; AGE DISTRIBUTION; AGED; ARTICLE; BODY MASS; BODY WEIGHT; CARDIOVASCULAR DISEASE; CIGARETTE SMOKING; CLINICAL FEATURE; CONTROLLED STUDY; CORONARY ARTERY DISEASE; DIABETES MELLITUS; DISEASE CLASSIFICATION; DISEASE REGISTRY; DYSLIPIDEMIA; EXTREME OBESITY; FEMALE; HEART LEFT VENTRICLE EJECTION FRACTION; HUMAN; HYPERTENSION; MAJOR CLINICAL STUDY; MALE; MORTALITY; OBESITY; PERCUTANEOUS CORONARY INTERVENTION; PREVALENCE; PRIORITY JOURNAL; ST SEGMENT ELEVATION MYOCARDIAL INFARCTION; TREATMENT OUTCOME; UNDERWEIGHT;

AGED; BODY MASS INDEX; BODY WEIGHT; ELECTROCARDIOGRAPHY; FEMALE; HOSPITAL MORTALITY; HUMANS; MALE; MIDDLE AGED; MYOCARDIAL INFARCTION; OBESITY, MORBID; QUALITY OF HEALTH CARE; REGISTRIES;

EID: 82955189273     PISSN: 07351097     EISSN: 15583597     Source Type: Journal    
DOI: 10.1016/j.jacc.2011.09.030     Document Type: Article

References (36)

1. National Heart, Lung, and Blood Institute Expert Panel Clinical guidelines on the identification, evaluation, and treatment of overweight and obesity in adults http://www.nhlbi.nih.gov/guidelines/obesity Accessed April 3, 2011
2. C.L. Ogden, S.Z. Yanovski, M.D. Carroll, and K.M. Flegal The epidemiology of obesity Gastroenterology 132 2007 2087 2102 (Pubitemid 46693751)
3. C.L. Ogden, M.D. Carroll, L.R. Curtin, M.A. McDowell, C.J. Tabak, and K.M. Flegal Prevalence of overweight and obesity in the United States, 19992004 JAMA 295 2006 1549 1555
4. R.H. Eckel, R.M. Krauss AHA Nutrition Committee American Heart Association call to action: obesity as a major risk factor for coronary heart disease Circulation 97 1998 2099 2100 (Pubitemid 28262114)
5. R. Wolk, P. Berger, R.J. Lennon, E.S. Brilakis, and V.K. Somers Body mass index: a risk factor for unstable angina and myocardial infarction in patients with angiographically confirmed coronary artery disease Circulation 108 2003 2206 2211 (Pubitemid 37363037)
6. E.B. Rimm, M.J. Stampfer, and E. Giovannucci Body size and fat distribution as predictors of coronary heart disease among middle-aged and older US men Am J Epidemiol 141 1995 1117 1127
7. R.C. Kaplan, S.R. Heckbert, C.D. Furberg, and B.M. Psaty Predictors of subsequent coronary events, stroke, and death among survivors of first hospitalized myocardial infarction J Clin Epidemiol 55 2002 654 664 (Pubitemid 34831058)
8. B.D. Hoit, E.A. Gilpin, A.A. Maisel, H. Henning, J. Carlisle, and J. Ross Jr Influence of obesity on morbidity and mortality after acute myocardial infarction Am Heart J 114 1987 1334 1341 (Pubitemid 18009488)
9. J.S. Rana, K.J. Mukamal, J.P. Morgan, J.E. Muller, and M.A. Mittleman Obesity and the risk of death after acute myocardial infarction Am Heart J 147 2004 841 846 (Pubitemid 38880995)
10. F. Lopez-Jimenez, S.J. Jacobsen, G.S. Reeder, S.A. Weston, R.A. Meverden, and V.L. Roger Prevalence and secular trends of excess body weight and impact on outcomes after myocardial infarction in the community Chest 125 2004 1205 1212 (Pubitemid 38501330)
11. A. Romero-Corral, V.M. Montori, and V.K. Somers Association of bodyweight with total mortality and with cardiovascular events in coronary artery disease: a systematic review of cohort studies Lancet 368 2006 666 678 (Pubitemid 44223694)
12. C.J. Lavie, R.V. Milani, S.M. Artham, D.A. Patel, and H.O. Ventura The obesity paradox, weight loss, and coronary disease Am J Med 122 2009 1106 1114
13. P.A. Ades, and P.D. Savage The obesity paradox: perception vs knowledge Mayo Clin Proc 85 2010 112 114
14. D.B. Diercks, M.T. Roe, and J. Mulgund The obesity paradox in non-ST-segment elevation acute coronary syndromes: results from the Can Rapid Risk Stratification of Unstable angina patients Suppress Adverse Outcomes With Early Implementation of the American College of Cardiology/American Heart Association Guidelines Quality Improvement Initiative Am Heart J 152 2006 140 148 (Pubitemid 44040849)
15. E.D. Peterson, M.T. Roe, and A.Y. Chen The NCDR ACTION Registry-GWTG: transforming contemporary acute myocardial infarction clinical care Heart 96 2010 1798 1802
16. M.T. Roe, J.C. Messenger, and W.S. Weintraub Treatments, trends, and outcomes of acute myocardial infarction and percutaneous coronary intervention J Am Coll Cardiol 56 2010 254 263
17. E.D. Peterson, M.T. Roe, and J.S. Rumsfeld A call to ACTION (Acute Coronary Treatment and Intervention Outcomes Network): a national effort to promote timely clinical feedback and support continuous quality improvement for acute myocardial infarction Circ Cardiovasc Qual Outcomes 2 2009 491 499
18. J.W. Hoekstra, C.V. Pollack Jr, and M.T. Roe Improving the care of patients with non-ST-elevation acute coronary syndromes in the emergency department: the CRUSADE initiative Acad Emerg Med 9 2002 1146 1155 (Pubitemid 35291543)
19. C.T. Chin, A.Y. Chen, and T.Y. Wang Risk adjustment for in-hospital mortality of contemporary patients with acute myocardial infarction: the Acute Coronary Treatment and Intervention Outcomes Network (ACTION) Registry-Get With the Guidelines (GWTG) acute myocardial infarction mortality model and risk score Am Heart J 161 2010 113 122
20. C.J. Lavie, R.V. Milani, and H.O. Ventura Obesity and cardiovascular disease: risk factor, paradox, and impact of weight loss J Am Coll Cardiol 53 2009 1925 1932
21. K.M. Flegal, M.D. Carroll, C.L. Ogden, and L.R. Curtin Prevalence and trends in obesity among US adults, 1999-2008 JAMA 303 2010 235 241
22. B.I. Truman, C.K. Smith, and K. Roy Rationale of regular reporting on health disparities and inequalitiesUnited States http://www.cdc.gov/mmwr/ preview/mmwrhtml/su6001a2.htm?s-cid=su6001a2-w Accessed March 28, 2011
23. S.R. Das, M.H. Drazner, and D.L. Dries Impact of body mass and body composition on circulating levels of natriuretic peptides: results from the Dallas Heart Study Circulation 112 2005 2163 2168 (Pubitemid 41475811)
24. D.R. Cottam, S.G. Mattar, and E. Barinas-Mitchell The chronic inflammatory hypothesis for the morbidity associated with morbid obesity: implications and effects of weight loss Obes Surg 14 2004 589 600 (Pubitemid 38716577)
25. A. El-Solh, P. Sikka, E. Bozkanat, W. Jaafar, and J. Davies Morbid obesity in the medical ICU Chest 120 2001 1989 1997 (Pubitemid 34053465)
26. A.N. Galanos, C.F. Pieper, P.S. Kussin SUPPORT Investigators Relationship of body mass index to subsequent mortality among seriously ill hospitalized patients Crit Care Med 25 1997 1962 1968 (Pubitemid 28007231)
27. F. Landi, G. Onder, G. Gambassi, C. Pedone, P. Carbonin, and R. Bernabei Body mass index and mortality among hospitalized patients Arch Intern Med 160 2000 2641 2644
28. D.E. Ray, S.C. Matchett, K. Baker, T. Wasser, and M.J. Young The effect of body mass index on patient outcomes in a medical ICU Chest 127 2005 2125 2131
29. A. Tremblay, and V. Bandi Impact of body mass index on outcomes following critical care Chest 123 2003 1202 1207 (Pubitemid 36444379)
30. R.W. Vaughan, S. Bauer, and L. Wise Volume and pH of gastric juice in obese patients Anesthesiology 43 1975 686 689
31. J.G. Kral Morbid obesity and related health risks Ann Intern Med 103 1985 1043 1047 (Pubitemid 16211929)
32. M. Valencia-Flores, A. Orea, and V.A. Castano Prevalence of sleep apnea and electrocardiographic disturbances in morbidly obese patients Obes Res 8 2000 262 269
33. S.A. Nasraway Jr, M. Albert, A.M. Donnelly, R. Ruthazer, S.A. Shikora, and E. Saltzman Morbid obesity is an independent determinant of death among surgical critically ill patients Crit Care Med 34 2006 964 970
34. G.C. Fonarow, P. Srikanthan, M.R. Costanzo, G.B. Cintron, and M. Lopatin An obesity paradox in acute heart failure: analysis of body mass index and inhospital mortality for 108,927 patients in the Acute Decompensated Heart Failure National Registry Am Heart J 153 2007 74 81 (Pubitemid 44880872)
35. L. Gruberg, N.J. Weissman, and R. Waksman The impact of obesity on the short-term and long-term outcomes after percutaneous coronary intervention: the obesity paradox? J Am Coll Cardiol 39 2002 578 584 (Pubitemid 34158151)
36. S. Uretsky, F.H. Messerli, and S. Bangalore Obesity paradox in patients with hypertension and coronary artery disease Am J Med 120 2007 863 870 (Pubitemid 47451305)