Regeneration of rodent small intestine tissue following implantation of scaffolds seeded with a novel source of smooth muscle cells

Regenerative Medicine

Volumn 6, Issue 6, 2011, Pages 721-731

  Basu, Joydeep ^a   Mihalko, Kim L ^b   Payne, Richard ^a   Rivera, Elias ^a   Knight, Toyin ^a   Genheimer, Christopher W ^a   Guthrie, Kelly I ^a   Sangha, Namrata ^a   Jayo, Manuel J ^a   Jain, Deepak ^a   Bertram, Timothy A ^a   Ludlow, John W ^a  

^a Tengion Inc   (United States)

^b CAROLINAS MEDICAL CENTER   (United States)

Author keywords

adipose; small intestine; smooth muscle cell; tissue engineering

Indexed keywords

BIOMATERIAL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL ISOLATION; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; HISTOLOGY; IN VIVO STUDY; INTESTINE INJURY; INTESTINE WALL; NONHUMAN; PRIORITY JOURNAL; RAT; SMOOTH MUSCLE FIBER; TISSUE ENGINEERING; TISSUE REGENERATION;

ANASTOMOSIS, SURGICAL; ANIMALS; FEMALE; GENE EXPRESSION REGULATION; INTESTINE, SMALL; MALE; MYOCYTES, SMOOTH MUSCLE; PROSTHESIS IMPLANTATION; RATS; RATS, INBRED LEW; REGENERATION; TISSUE ENGINEERING; TISSUE SCAFFOLDS;

EID: 82955187007     PISSN: 17460751     EISSN: 1746076X     Source Type: Journal    
DOI: 10.2217/rme.11.78     Document Type: Article

References (30)

1. Warner BW. Tissue engineered small intestine, a viable clinical option? Ann. Surg. 240(5), 755-756 (2004) (Pubitemid 39425766)
2. Gabe SM, Day RM, Boccacini A. Tissue engineering of the small intestine.In: Encyclopedia of Biomaterials and Biomedicine, Wnek GE, Bowlin GL (Eds). Informa Healthcare, London, UK (2004)
3. Grikscheit TC, Siddique A, Ochoa ER et al. Tissue engineered small intestine improves recovery after massive small bowel resection. Ann. Surg. 240(5), 748-754 (2004) (Pubitemid 39425765)
4. Messing B, Crenn P, Beau P et al. Long term survival and parenteral nutrition dependence in adult patients with the short bowel syndrome. Gastroentology 117(5), 1043-1050 (1999) (Pubitemid 29512662)
5. Krupnick AS, Morris JB. The long term results of resection and multiple resections in Crohn's disease. Semin. Gastrointest. Dis. 11(1), 41-51 (2000) (Pubitemid 30106154)
6. Bianchi A. Experience with longitudinal intestinal lengthening and tailoring. Eur. J. Pediatr. Surg. 9(4), 256-259 (1999) (Pubitemid 29463088)
7. Warner BW, Vanderhoof JA, Reyes JD. What's new in the management of short gut syndrome in children. J. Am. Coll. Surg. 190(6), 725-736 (2000) (Pubitemid 30368485)
8. Beckstead BL, Pan S, Bhrany AD et al. Esophageal epithelial cell interaction with synthetic and natural scaffolds for tissue engineering. Biomaterials 26(31), 6217-6228 (2005) (Pubitemid 40826990)
9. Furth ME, Atala A, Van Dyke ME. Smart biomaterials design for tissue engineering and regenerative medicine. Biomaterials 28(34), 5068-5073 (2007) (Pubitemid 47488490)
10. Atala A. Recent developments in tissue engineering and regenerative medicine. Curr. Opin. Pediatr. 18(2), 167-171(2006)
11. Becker C, Jakse G. Stem cells for regeneration of urological structures. Eur. Urol. 51(5), 1217-1228 (2007) (Pubitemid 46436324)
12. Frimberger D, Lin HK, Kropp BR. The use of tissue engineering and stem cells in bladder regeneration. Regen. Med. 1(4), 425-435 (2006)
13. Roth CC, Kropp BP. Recent advances in urologic tissue engineering. Curr. Urol. Rep. 10(2), 119-125 (2009)
14. Wood D, Southgate J. Current status of tissue engineering in urology. Curr. Opin. Urol. 18(6), 564-569 (2008)
15. Basu J, Ludlow JW. Platform technologies for tubular organ regeneration. Trends Biotech. 28(10), 526-533 (2010).Principal theme is the importance of a biodegradable scaffold nucleated with a population of smooth muscle cells. This article focuses on identifying the elements of this platform that have facilitated the transition of tubular organ regeneration from academic proof-of-concept to commercial viability
16. Jayo MJ, Jain D, Ludlow JW et al. Long term durability, tissue regeneration and neo-organ growth during skeletal maturation with a neo-bladder augmentation construct. Regen. Med. 3(5), 671-682 (2008).Regenerating native-like internal organs using cell scaffold products has the potential to reduce morbidity and mortality associated with organ transplantation or reconstructive surgery.
17. Urita Y, Komuro H, Chen G et al. Regeneration of the esophagus using gastric acellular matrix: An experimental study in a rat model. Pediatr. Surg. Int. 23, 21-26 (2007) (Pubitemid 46020471)
18. Grikscheit T, Ochoa ER, Srinivasan A et al. Tissue-engineered esophagus: Experimental substitution by onlay patch or interposition. J. Thorac. Cardiovas. Surg. 126(2), 537-544 (2003) (Pubitemid 37048523)
19. Kim SS, Penkala R, Abrahimi P. A perfusion bioreactor for intestinal tissue engineering. J. Surg. Res. 142(2), 327-331 (2007) (Pubitemid 47418831)
20. Grikscheit TC, Ochoa ER, Ramsanahie A et al. Tissue-engineered large intestine resembles native colon with appropriate in vitro physiology and architecture. Ann. Surg. 238(1) 35-41 (2003) (Pubitemid 38176405)
21. Basu J, Genheimer C, Guthrie KI et al. Expansion of the human adipose-derived stromal vascular cell fraction yields a population of smooth muscle cells with markedly distinct phenotypic and functional properties relative to mesenchymal stem cells. Tissue Eng. Part C Methods 17(8), 843-860 (2011).Demonstrates that adipose tissue is an alternative source of smooth muscle cells, which may be used in tissue engineered and regenerative medicine products
22. Bhrany AD, Beckstead BL, Lang TC et al. Development of an esophagus acellular matrix tissue scaffold. Tissue Eng. 12(2), 319-330 (2007)
23. Badylak SF, Vorp DA, Spievak AR et al. Esophageal reconstruction with ECM and muscle tissue in a dog model. J. Surg. Res. 128(1), 87-97 (2005) (Pubitemid 41188215)
24. Marzaro M, Vigolo S, Oselladore B et al. In vitro and in vivo proposal of an artificial esophagus. J. Biomed. Mater. Res. Part A 77(4), 795-801 (2006) (Pubitemid 47233560)
25. Hori Y, Nakamura T, Kimura D et al. Experimental study on tissue engineering of the small intestine by mesenchymal stem cell seeding. J. Surg. Res. 102(2), 156-160 (2002) (Pubitemid 34969462)
26. Nakase Y, Hagiwara A, Nakamura T et al. Tissue engineering of small intestinal tissue using collagen sponge scaffolds seeded with smooth muscle cells. Tissue Eng. 12(2), 403-412 (2006)
27. Nakase Y, Nakamura T, Kin S et al. Endocrine cell and nerve regeneration in autologous in situ tissue-engineered small intestine. J. Surg. Res. 137(1), 61-68 (2007) (Pubitemid 44879428)
28. Sala FG, Kunisaki SM, Ochoa ER et al. Tissue-engineered small intestine and stomach form from autologous tissue in a preclinical large animal model. J. Surg. Res. 156(2), 205-212 (2009)
29. Mimeault M, Hauke R, Batra SK. Stem cells: A revolution in therapeutics - recent advances in stem cell biology and their therapeutic applications in regenerative medicine and cancer therapies. Clin. Pharmacol. Ther. 82(3), 252-264 (2007) (Pubitemid 47260547)
30. Booth C, O'Shea J. Isolation and culture of intestinal epithelial cells. In:Culture of Epithelial Cells (2nd Edition) Freshney RI, Freshney MG (Eds). Wiley-Liss, New York, NY, USA (2002).