Venous thromboembolism does not share strong familial susceptibility with ischemic stroke a nationwide family study in Sweden

Circulation: Cardiovascular Genetics

Volumn 4, Issue 5, 2011, Pages 484-490

  Zöller, Bengt ^a,c   Li, Xinjun ^a   Ohlsson, Henrik ^a   Sundquist, Jan ^b   Sundquist, Kristina ^a  

^a LUND UNIVERSITY   (Sweden)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c LUND UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Family history; Genetics; Ischemic stroke; Risk factors; Thrombosis

Indexed keywords

ARTICLE; BRAIN ISCHEMIA; CAUSE OF DEATH; DISEASE PREDISPOSITION; DISEASE REGISTRY; FAMILIAL SUSCEPTIBILITY; HOSPITALIZATION; HUMAN; PRIORITY JOURNAL; PROGENY; RISK ASSESSMENT; SIBLING; SPOUSE; SWEDEN; VENOUS THROMBOEMBOLISM;

ADOLESCENT; ADULT; AGED; CHILD; CHILD, PRESCHOOL; DISEASE SUSCEPTIBILITY; FAMILY; FEMALE; HUMANS; INFANT; INFANT, NEWBORN; MALE; MIDDLE AGED; MUTATION; ODDS RATIO; REGISTRIES; RISK FACTORS; STROKE; SWEDEN; VENOUS THROMBOEMBOLISM;

EID: 82955173752     PISSN: 1942325X     EISSN: 19423268     Source Type: Journal    
DOI: 10.1161/CIRCGENETICS.111.959882     Document Type: Article

References (35)

1. Agnelli G, Becattini C. Venous thromboembolism and atherosclerosis: common denominators or different diseases? J Thromb Haemost. 2006; 4:1886-1890. (Pubitemid 44226763)
2. Martinelli I, Bucciarelli P, Mannucci PM. Thrombotic risk factors: basic pathophysiology. Crit Care Med. 2010;38:S3-S9.
3. Prandoni P, Bilora F, Marchiori A, Bernardi E, Petrobelli F, Lensing AW, Prins MH, Girolami A. An association between atherosclerosis and venous thrombosis. N Engl J Med. 2003;348:1435-1441. (Pubitemid 36407172)
4. Schulman S, Lindmarker P, Holmström M, Lärfars G, Carlsson A, Nicol P, Svensson E, Ljungberg B, Viering S, Nordlander S, Leijd B, Jahed K, Hjorth M, Linder O, Beckman M. Postthrombotic syndrome, recurrence, and death 10 years after the first episode of venous thromboembolism treated with warfarin for 6 weeks or 6 months. J Thromb Haemost. 2006;4:734-742.
5. Sørensen HT, Horvath-Puho E, Pedersen L, Baron JA, Prandoni P. Venous thromboembolism and subsequent hospitalisation due to acute arterial cardiovascular events: a 20-year cohort study. Lancet. 2007;370: 1773-1779. (Pubitemid 350137491)
6. Johnston SC, Mendis S, Mathers CD. Global variation in stroke burden and mortality: estimates from monitoring, surveillance, and modelling. Lancet Neurol. 2009;8:345-354.
7. Casas JP, Hingorani AD, Bautista LE, Sharma P. Meta-analysis of genetic studies in ischemic stroke: thirty-two genes involving approximately 18,000 cases and 58,000 controls. Arch Neurol. 2004;61: 1652-1661. (Pubitemid 39463422)
8. Bentley P, Peck G, Smeeth L, Whittaker J, Sharma P. Causal relationship of susceptibility genes to ischemic stroke: comparison to ischemic heart disease and biochemical determinants. PLoS One. 2010;5:e9136.
9. Juul K, Tybjaerg-Hansen A, Steffensen R, Kofoed S, Jensen G, Nordestgaard BG. Factor V Leiden: The Copenhagen City Heart Study and 2 meta-analyses. Blood. 2002;100:3-10. (Pubitemid 35177420)
10. Burton PR, Tobin MD, Hopper JL. Key concepts in genetic epidemiology. Lancet. 2005;366:941-951. (Pubitemid 41265670)
11. Risch N. The genetic epidemiology of cancer: interpreting family and twin studies and their implications for molecular genetic approaches. Cancer Epidemiol Biomarkers Prev. 2001;10:733-741. (Pubitemid 32695152)
12. Quist-Paulsen P, Naess IA, Cannegieter SC, Romundstad PR, Christiansen SC, Rosendaal FR, Hammerstrøm J. Arterial cardiovascular risk factors and venous thrombosis: results from a population-based, prospective study (the HUNT 2). Haematologica. 2010;95:119-125.
13. Bezemer ID, van der Meer FJ, Eikenboom JCJ, Rosendaal FR, Doggen CJ. The value of family history as a risk indicator for venous thrombosis. Arch Intern Med. 2009;169:610-615.
14. Noboa S, Le Gal, Lacut K, Mercier B, Leroyer C, Nowak E, Mottier D, Oger E, for the EDITH Collaborative Study Group. Family history as a risk factor for venous thromboembolism. Thromb Res. 2008;122: 624-629.
15. Dowling NF, Austin H, Diley A, Whitsett C, Evatt BL Hooper WC. The epidemiology of venous thromboembolism in Caucasians and African- Americans: the GATE Study. J Thromb Haemost. 2003;1:80-87.
16. Zöller B, Li X, Sundquist J, Sundquist K. Parental history and venous thromboembolism: a nationwide study of age and sex-specific familial risks in Sweden. J Thromb Haemost. 2011;9:64-70.
17. Rosendaal FR, Reitsma PH. Genetics of venous thrombosis. J Thromb Haemost. 2009;7:301-304.
18. Hemminki K, Shu X, Li X, Ji J, Sundquist J, Sundquist K. Familial risks for hospitalization with endocrine diseases. J Clin Endocrinol Metab. 2008;93:4755-4758.
19. Sundquist K, Li X, Hemminki K. Familial risk of ischemic and hemorrhagic stroke: a large-scale study of the Swedish population. Stroke. 2006;37:1668-1673. (Pubitemid 44297710)
20. Hemminki K, Li X, Sundquist J, Sundquist K. Familial risks for type 2 diabetes in. Sweden Diabetes Care. 2010;33:293-297.
21. Hemminki K, Li X, Sundquist K, Sundquist J. Shared familial risk factors between cancer and RA patients. Rheumatology. 2008;47: 549-551.
22. Socialstyrelsen. Patientregistret 1987-1996. Kvalitet och innehåll. Stockholm: Epidemiologiskt Centrum, Socialstyrelsen 1998.
23. Rosengren A, Fredén M, Hansson P-O, Wilhelmsen L, Wedel H, Eriksson H. Psychosocial factors and venous thromboembolism: a long-term follow-up study of Swedish men. J Thromb Haemost. 2008; 6:558-564. (Pubitemid 351404921)
24. Lindblad U, Råstam L, Ranstam J, Peterson M. Validity of register data on acute myocardial infarction and acute stroke: the Skaraborg Hypertension Project. Scand J Soc Med. 1993;21:3-9. (Pubitemid 23092050)
25. Souto JC, Almasy L, Borrell M, Blanco-Vaca F, Mateo J, Soria JM, Coll I, Felices R, Stone W, Fontcuberta J, Blangero J. Genetic susceptibility to thrombosis and its relationship to physiological risk factors: the GAIT study. Am J Hum Genet. 2000;67:1452-1459.
26. Lichtenstein P, Yip BH, Björk C, Pawitan Y, Cannon TD, Sullivan PF, Hultman CH. Common genetics determinants of schizophrenia and bipolar disorders in Swedish families: a population-based study. Lancet. 2009;373:234-239.
27. Seegers WH, McCoy LE, Groben HD, Sakuragawa N, Agrawal BBL. Purification and some properties of autoprothrombin II-A: an anticoagulant perhaps also related to fibrinolysis. Thromb Res. 1972;1: 443-460.
28. Esmon CT, Owen WG. Identification of an endothelial cell cofactor for thrombin-catalyzed activation of protein C. Proc Natl Acad Sci U S A. 1981;4:2249-2252. (Pubitemid 11119893)
29. Bauer KA. Activation markers of coagulation. Baillieres Best Pract Res Clin Haematol. 1999;12:387-406. (Pubitemid 30312618)
30. Smith A, Patterson Y, arnell J, Rumley A, Ben Shlomo Y, Lowe G. Which hemostatic markers add to the predictive value of conventional risk factors for coronary heart disease and ischemic stroke? The Caerphilly Study. Circulation. 2005;112:3080-3087. (Pubitemid 43113439)
31. Zöller B, Li X, Sundquist J, Sundquist K. Familial risks for unusual forms of venous thrombosis: a nationwide epidemiological study in Sweden. J Intern Med. 2011;270:158-165.
32. Lanktree MB, Dichgans M, Hegele RA. Advances in genomic analysis of stroke: what have we learned and where are we headed? Stroke. 2010; 41:825-832.
33. Denny JC, Ritchie MD, Basford MA, Pulley JM, Bastarache L, Brown- Gentry K, Wang D, Masys DR, Roden DM, Crawford DC. PheWAS: demonstrating the feasibility of a phenome-wide scan to discover genedisease associations. Bioinformatics. 2010;26:1205-1210.
34. Trégouet DA, Heath S, Saut N, Biron-Andreani C, Schved JF, Pernod G, Galan P, Drouet L, Zelenika D, Juhan-Vague I, Alessi MC, Tiret L, Lathrop M, Emmerich J, Morange PE. Common susceptibility alleles are unlikely to contribute as strongly as the FV and AB0 loci to VTE risk: results from a GWAS approach. Blood. 2009;113:5298-5303.
35. Statens beredning fö r medicinsk utvärdering (SBU). Blodproppförebyggande, diagnostik och behandling av venös tromboembolism SBU-rapport 158, 2002:I-II.