A screening for essential cell growth-related genes involved in arsenite toxicity in Saccharomyces cerevisiae

Journal of Toxicological Sciences

Volumn 36, Issue 6, 2011, Pages 859-861

  Takahashi, Tsutomu ^a   Satake, Shohei ^a   Hirose, Ken ichiro ^a   Hwang, Gi Wook ^a   Naganuma, Akira ^a  

^a TOHOKU UNIVERSITY   (Japan)

Author keywords

Arsenite; ERG8; RKI1; Yeast; YPT1

Indexed keywords

ARSENIC TRIOXIDE; FUNGAL PROTEIN; PROTEIN ERG8; PROTEIN RKI1; PROTEIN YPT1; UNCLASSIFIED DRUG;

ARTICLE; FUNGAL CELL; FUNGAL GENE; FUNGAL STRAIN; FUNGUS GROWTH; GENETIC SCREENING; MOLECULAR MECHANICS; NONHUMAN; SACCHAROMYCES CEREVISIAE; SENSITIVITY ANALYSIS;

EID: 82855163179     PISSN: 03881350     EISSN: 18803989     Source Type: Journal    
DOI: 10.2131/jts.36.859     Document Type: Article

References (19)

1. Alam, M.G., Allinson, G., Stagnitti, F., Tanaka, A. and Westbrooke, M. (2002): Arsenic contamination in Bangladesh groundwater: a major environmental and social disaster. Int. J. Environ. Health Res., 12, 235-253.
2. Aouida, M., Page, N., Leduc, A., Peter, M. and Ramotar, D. (2004): A genome-wide screen in Saccharomyces cerevisiae reveals altered transport as a mechanism of resistance to the anticancer drug bleomycin. Cancer Res., 64, 1102-1109.
3. Benito-Moreno, R.M., Miaczynska, M., Bauer, B.E., Schweyen, R.J. and Ragnini, A. (1994): Mrs6p, the yeast homologue of the mammalian choroideraemia protein: immunological evidence for its function as the Ypt1p Rab escort protein. Curr. Genet., 27, 23-25.
4. Breitkreutz, A., Choi, H., Sharom, J.R., Boucher, L., Neduva, V., Larsen, B., Lin, Z.Y., Breitkreutz, B.J., Stark, C., Liu, G., Ahn, J., Dewar-Darch, D., Reguly, T., Tang, X., Almeida, R., Qin, Z.S., Pawson, T., Gingras, A.C., Nesvizhskii, A.I. and Tyers, M. (2010): A global protein kinase and phosphatase interaction network in yeast. Science, 328, 1043-1046.
5. Breslow, D.K., Cameron, D.M., Collins, S.R., Schuldiner, M., Stewart-Ornstein, J., Newman, H.W., Braun, S., Madhani, H.D., Krogan, N.J. and Weissman, J.S. (2008): A comprehensive strategy enabling high-resolution functional analysis of the yeast genome. Nat. Methods, 5, 711-718.
6. Furuchi, T., Takahashi, T., Tanaka, S., Nitta, K. and Naganuma, A. (2004): Functions of yeast helicase Ssl2p that are essential for viability are also involved in protection from the toxicity of adriamycin. Nucleic Acids Res., 32, 2578-2585.
7. Hwang, G.W., Lee, J.Y., Ryoke, K., Matsuyama, F., Kim, J.M., Takahashi, T. and Naganuma, A. (2011): Gene expression profiling using DNA microarray analysis of the cerebellum of mice treated with methylmercury. J. Toxicol. Sci., 36, 389-391.
8. Jomova, K., Jenisova, Z., Feszterova, M., Baros, S., Liska, J., Hudecova, D., Rhodes, C.J. and Valko, M. (2011): Arsenic: toxicity, oxidative stress and human disease. J. Appl. Toxicol., 31, 95-107.
9. Kondo, H., Nakamura, Y., Dong, Y.X., Nikawa, J. and Sueda, S. (2004): Pyridoxine biosynthesis in yeast: participation of ribose 5-phosphate ketol-isomerase. Biochem. J., 379, 65-70.
10. Kumagai, Y. and Sumi, D. (2007): Arsenic: signal transduction, transcription factor, and biotransformation involved in cellular response and toxicity. Annu. Rev. Pharmacol. Toxicol., 47, 243-262.
11. Miaczynska, M., Wagner, W., Bauer, B.E., Schweyen, R.J. and Ragnini, A. (2001): Ypt protein prenylation depends on the interplay among levels of Rab escort protein and geranylgeranyl diphosphate in yeast cells. Yeast, 18, 697-709.
12. Petrick, J.S., Jagadish, B., Mash, E.A. and Aposhian, H.V. (2001): Monomethylarsonous acid (MMA(III) and arsenite: LD(50) in hamsters and in vitro inhibition of pyruvate dehydrogenase. Chem. Res. Toxicol., 14, 651-656.
13. Ratnaike, R.N. (2003): Acute and chronic arsenic toxicity. Postgrad. Med. J., 79, 391-396.
14. Shi, H., Shi, X. and Liu, K.J. (2004): Oxidative mechanism of arsenic toxicity and carcinogenesis. Mol. Cell. Biochem., 255, 67-78.
15. Sumi, D., Shinkai, Y. and Kumagai, Y. (2010): Signal transduction pathways and transcription factors triggered by arsenic trioxide in leukemia cells. Toxicol. Appl. Pharmacol., 244, 385-392.
16. Tarassov, K., Messier, V., Landry, C.R., Radinovic, S., Serna, Molina, M.M., Shames I., Malitskaya, Y., Vogel, J., Bussey, H. and Michnick, S.W. (2008): An in vivo map of the yeast protein interactome. Science, 320, 1465-1470.
17. Thorsen, M., Perrone, G.G., Kristiansson, E., Traini, M., Ye, T., Dawes, I.W., Nerman, O. and Tamas, M.J. (2009): Genetic basis of arsenite and cadmium tolerance in Saccharomyces cerevisiae. BMC Genomics, 10, 105.
18. Tsay, Y.H. and Robinson, G.W. (1991): Cloning and characterization of ERG8, an essential gene of Saccharomyces cerevisiae that encodes phosphomevalonate kinase. Mol. Cell. Biol., 11, 620-631.
19. Zhou, X., Arita, A., Ellen, T.P., Liu, X., Bai, J., Rooney, J.P., Kurtz, A.D., Klein, C.B., Dai, W., Begley, T.J. and Costa, M. (2009): A genome-wide screen in Saccharomyces cerevisiae reveals pathways affected by arsenic toxicity. Genomics, 94, 294-307.