Enhanced gene expression promoted by the quantized folding of pDNA within polyplex micelles

Biomaterials

Volumn 33, Issue 1, 2012, Pages 325-332

  Osada, Kensuke ^a   Shiotani, Tomonori ^a   Tockary, Theofilus A ^a   Kobayashi, Daigo ^a   Oshima, Hiroki ^a   Ikeda, Sorato ^a   Christie, Ronald J ^a,b   Itaka, Keiji ^a,b   Kataoka, Kazunori ^a,b  

^a UNIVERSITY OF TOKYO   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

DNA; Gene transfer; In vitro test; In vivo test; Micelle; Nanoparticle

Indexed keywords

CELL-FREE; CULTURED CELL; DOUBLE STRANDED DNA; ENHANCED GENE EXPRESSION; FOLDING MECHANISM; GENE TRANSFECTION; IN VITRO TEST; IN VIVO TEST; L-LYSINE; MICELLE FORMATION; PACKAGING STRUCTURE; PLASMID DNA (PDNA); POLYPLEXES; ROD STRUCTURE; SEGMENT LENGTHS; SKELETAL MUSCLE; THERAPEUTIC GENES;

AMINO ACIDS; DNA; ETHYLENE; GENE THERAPY; GENE TRANSFER; GLYCOLS; MICELLES; NANOPARTICLES; POLYETHYLENE GLYCOLS; SPHERES;

GENE EXPRESSION;

DOUBLE STRANDED DNA; PLASMID DNA;

ARTICLE; CONTROLLED STUDY; GENE DELIVERY SYSTEM; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; MICELLE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROCESSING;

ANIMALS; CELL LINE, TUMOR; DNA; HUMANS; MICE; MICELLES; MICROSCOPY, ATOMIC FORCE; MICROSCOPY, ELECTRON, TRANSMISSION; NANOPARTICLES; NUCLEIC ACID CONFORMATION; PLASMIDS;

MUS;

EID: 82855161309     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2011.09.046     Document Type: Article

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