Degree of tumor regression after preoperative chemo-radiotherapy in locally advanced rectal cancer-Preliminary results

Reports of Practical Oncology and Radiotherapy

Volumn 16, Issue 6, 2011, Pages 237-242

  Mihaylova, Iglika ^a   Parvanova, Vesselina ^a   Velikova, Chanita ^a   Kurteva, Galia ^a   Ivanova, Doroteya ^b  

^a National Oncology Center Bulgaria   (Bulgaria)

^b Tokuda Hospital   (Bulgaria)

Author keywords

Chemo radiotherapy; Preoperative treatment; Rectal cancer; Tumor regression grade

Indexed keywords

CAPECITABINE;

ADULT; ADVANCED CANCER; ARTICLE; CANCER ADJUVANT THERAPY; CANCER CHEMOTHERAPY; CANCER GRADING; CANCER RADIOTHERAPY; CANCER REGRESSION; CANCER SURGERY; CANCER SURVIVAL; CLINICAL ARTICLE; ENTERITIS; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; MALE; POSTOPERATIVE PERIOD; PREOPERATIVE RADIOTHERAPY; PREOPERATIVE TREATMENT; RADIATION DOSE; RECTUM CARCINOMA;

EID: 82755197857     PISSN: 15071367     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.rpor.2011.06.008     Document Type: Article

References (14)

1. Adjuvant radiotherapy for rectal cancer: a systematic overview of 8507 patients from 22 randomized trials. Lancet 2001, 358:1291-1304. Colorectal cancer collaborative group.
2. Dworak O., Keilholz L., Hoffmann A. Pathological features of rectal cancer after preoperative radiochemotherapy. Int J Colorect Dis 1997, 12:19-23.
3. Ryan R. Pathological response following long-course neoadjuvant chemoradiotherapy for locally advanced rectal cancer. Histopathology 2005, 47:141-146.
4. NCCN Guidelines™ Version 2.2011 Rectal cancer.
5. Maura N.I. Damjanov Histopathology of colorectal cancer after neoadjuvant chemoradiation therapy. Pathol J 2009, 3:91-98.
6. Shia J., Guillem J., Moore H., et al. Patterns of morphologic alteration in residual rectal carcinoma following preoperative chemoradiation and their association with long-term outcome. Am J Surg Pathol 2004, 28:215-223.
7. Rubbria-Brandt L., Giostra E., Brezault C., et al. Importance of histological tumor response assessment in predicting the outcome in patients with colorectal liver metastases treated with neoadjuvant chemotherapy followed by liver surgery. Ann Oncol 2007, 18:299-304.
8. Blazer D., Kishi Y., Maru D. Pathologic response to preoperative chemotherapy: a new outcome end point after resection of hepatic colorectal metastases. J Clin Oncol 2008 Nov 20, 26(33):5344-5351.
9. Gavioli M., Luppi G., Losi L., et al. Incidence and clinical impact of sterilized disease and minimal residual disease after preoperative radiochemotherapy for rectal cancer. Dis Colon Rectum 2005, 48:1851-1857.
10. UICC TNM supplement 1993 1993, Springer, Berlin/Heidelberg/New York. P. Hermanek, D.E. Henson, R.V.P. Hutter, L.H. Sobin (Eds.).
11. Hiotis S., Weber S., Cohen A., et al. Assessing the predictive value of clinical complete response to neoadjuvant therapy for rectal cancer: an analysis of 488 patients. J Am Coll Surg 2002, 194:131-135.
12. Shia J., Tickoo S., Guillem J., et al. Increased endocrine cells intreated rectal adenocarcinomas. Am J Surg Pathol 2002, 26:863-872.
13. Picciocchi A., Coco C., Magistrelli P., et al. Concomitant preoperative radiochemotherapy in operable locally advanced rectal cancer. Dis Colon Rectum 1994, 37(Suppl.):69-72.
14. AJCC Cancer Staging Manual 2010, Springer, NY. 7th ed. S.B. Edge, D. Byrd, C. Compton (Eds.).