Urine-concentrating defects exacerbate with age in male offspring with a low-nephron endowment

American Journal of Physiology - Renal Physiology

Volumn 301, Issue 6, 2011, Pages

  Singh, Reetu R ^a   Denton, Kate M ^a   Bertram, John F ^a   Dowling, John ^b   Moritz, Karen M ^c  

^a MONASH UNIVERSITY   (Australia)

^b MONASH MEDICAL CENTRE   (Australia)

^c UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

Dehydration; Glomerular; Nephron number; Uninephrectomy; Vasopressin

Indexed keywords

AQUAPORIN 2; VASOPRESSIN; VASOPRESSIN V2 RECEPTOR;

AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHRONIC KIDNEY DISEASE; CONTROLLED STUDY; DEHYDRATION; DISEASE EXACERBATION; FETUS; GESTATIONAL AGE; GLOMERULUS FILTRATION RATE; HYPERTENSION; KIDNEY CONCENTRATING CAPACITY; KIDNEY DYSFUNCTION; MALE; MEAN ARTERIAL PRESSURE; NEPHRON; NONHUMAN; PRIORITY JOURNAL; PROGENY; RAM (SHEEP); UNINEPHRECTOMY; URINE OSMOLALITY; VASOPRESSIN BLOOD LEVEL; VASOPRESSIN RELEASE; WATER DEPRIVATION;

EID: 82755191660     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00463.2011     Document Type: Article

References (47)

1. Athanazio DA, Sweet GM, Silva CA, dos-Santos WL. Semiquantitative and semi-automated morphometric evaluation of chronic lesions in renal biopsies. Int Urol Nephrol 41: 643-651, 2009.
2. Barker D, Bagby S. Developmental antecedents of cardiovascular disease: a historical perspective. J Am Soc Nephrol 16: 2537-2544, 2005.
3. Boone M, Deen P. Physiology and pathophysiology of the vasopressinregulated renal water reabsorption. Pflügers Arch 456: 1005-1024, 2008.
4. Brenner BM, Mackenzie HS. Nephron mass as a risk factor for progression of renal disease. Kidney Int Suppl 63: S124-S127, 1997.
5. Combet S, Geffroy N, Berthonaud V, Dick B, Teilet L, Verbavatz J, Corman B, Trinh-Trang-Tan M. Correction of age-related polyuria by dDAVP: molecular analysis of aquaporins and urea transporters. Am J Physiol Renal Physiol 284: F199-F208, 2003.
6. Combet S, Gouraud S, Gobin R, Berthonaud V, Geelen G, Corman B, Verbavatz JM. Aquaporin-2 downregulation in kidney medulla of aging rats is posttranscriptional and is abolished by water deprivation. Am J Physiol Renal Physiol 294: F1408-F1414, 2008.
7. Combet S, Teillet L, Geelen G, Pitrat B, Gobin R, Nielsen S, Trinh-Trang-Tan M. Food restriction prevents age-related polyuria by vasopressin-dependent recruitment of aquaporins and urea transporters. Am J Physiol Renal Physiol 281: F1123-F1131, 2001.
8. Dodic M, Abouantoun T, O'Connor A, Wintour EM, Moritz KM. Programming effects of short prenatal exposure to dexamethasone in sheep. Hypertension 40: 729-734, 2002.
9. Dodic M, May C, Wintour E, Coghlan J. An early prenatal exposure to excess glucocorticoid leads to hypertensive offspring in sheep. Clin Sci (Lond) 94: 149-155, 1998.
10. Donahue J, Lowenthal D. Nocturnal polyuria in the elderly person. Am J Med Sci 314: 232-238, 1997.
11. Garcia Nieto VM, Yanes MI, Zamorano MM, Gonzalez MJ, Aros CP, Garin EH. Renal concentrating capacity as a marker for glomerular filtration rate. Acta Paediatr 97: 96-99, 2008.
12. Hilliard LM, Nematbakhsh M, Kett MM, Teichman E, Sampson AK, Widdop RE, Evans RG, Denton KM. Gender differences in pressurenatriuresis and renal autoregulation: role of the Angiotensin type 2 receptor. Hypertension 57: 275-282, 2011.
13. Hoppe CC, Evans RG, Moritz KM, Cullen-McEwen LA, Fitzgerald SM, Dowling J, Bertram JF. Combined prenatal and postnatal protein restriction influences adult kidney structure, function and arterial pressure. Am J Physiol Regul Integr Comp Physiol 292: R462-R469, 2007.
14. Ijzerman R, Stehouwer C, Geus ED, Weissenbruch MV, Waal-Delemarre HVD, Boomsma D. Low birth weight is associated with increased sympathetic activity: dependence on genetic factors. Circulation 108: 566-571, 2003.
15. Illius A, Jessop N. Metabolic constraints on voluntary intake in ruminants. J Anim Sci 74: 3052-3062, 1996.
16. Kett MM, Denton KM. Renal programming: cause for concern? Am J Physiol Regul Integr Comp Physiol 300: R791-R803, 2011.
17. Kwon TH, Frokiær J, Knepper M, Nielsen S. Reduced AQP1, -2, and -3 levels in kidney of rats with CRF induced by surgical reduction in renal mass. Am J Physiol Renal Physiol 275: F724-F741, 1998.
18. Langley-Evans S, Welham S, Jackson A. Fetal exposure to a maternal low protein diet impairs nephrogenesis and promotes hypertension in the rat. Life Sci 64: 965-974, 1999.
19. Luyckx VA, Brenner BM. Low birth weight, nephron number, and kidney disease. Kidney Int 68: S68-S77, 2005.
20. Marples D, Knepper M, Christensen E, Nielsen S. Redistribution of aquaporin-2 water channels induced by vasopressin in the rat kidney inner medullary collecting duct. Am J Physiol Cell Physiol 269: C655-C664, 1995.
21. Michell A, Moss P. Differences between sheep excreting sodium predominantly in their urine or in their faeces: the effect of changes in sodium intake. Exp Physiol 77: 799-805, 1992.
22. Moritz K, Wintour E. Functional development of the meso-metanephros. Pediatr Nephrol 13: 171-178, 1999.
23. Moritz KM, Jefferies A, Wong J, Wintour EM, Dodic M. Reduced renal reserve and increased cardiac output in adult female sheep uninephrectomized as fetuses. Kidney Int 67: 822-828, 2005.
24. Moritz KM, Wintour EM, Dodic M. Fetal uninephrectomy leads to postnatal hypertension and compromised renal function. Hypertension 39: 1071-1076, 2002.
25. Nowik M, Kampik NB, Mihailova M, Eladari D, Wagner CA. Induction of metabolic acidosis with ammonium chloride (NH4Cl) in mice and rats-species differences and technical considerations. Cell Physiol Biochem 26: 1059-1072, 2010.
26. Oliverio M, Delnomdedieu M, Best C, Li P, Morris M, Callahan M, Johnson G, Smithies O, Coffman T. Abnormal water metabolism in mice lacking the type 1A receptor for ANG II. Am J Physiol Renal Physiol 278: F75-F82, 2000.
27. Park R, Congiu M, Denton D, McKinley M. Natriuresis induced by arginine vasopressin infusion in sheep. Am J Physiol Renal Fluid Electrolyte Physiol 249: F799-F805, 1985.
28. Pedersen E, Thomsen I, Lauridsen T. Abnormal function of the vasopressin-cyclic-AMP-aquaporin2 axis during urine concentrating and diluting in patients with reduced renal function. A case control study. BMC Nephrol 11: 1-10, 2010.
29. Rowe J, Shock N, Defronzo R. The influence of age on the renal response to water deprivation in man. Nephron 17: 270-278, 1976.
30. Sahajpal V, Ashton N. Increased glomerular angiotensin II binding in rats exposed to a maternal low protein diet in utero. J Physiol 563: 193-201, 2005.
31. Sampson AK, Moritz KM, Jones ES, Flower RL, Widdop RE, Denton KM. Enhanced angiotensin II type 2 receptor mechanisms mediate decreases in arterial pressure attributable to chronic low-dose angiotensin II in female rats. Hypertension 52: 666-671, 2008.
32. Shi Y, Li C, Thomsen K, Jorgensen T, Knepper M, Nielsen S, Djurhuus J, Frokiær J. Neonatal ureteral obstruction alters expression of renal sodium transporters and aquaporin water channels. Kidney Int 66: 203-215, 2004.
33. Shwartz J, Reid I. Role of vasopressin in blood pressure regulation in conscious water-deprived dogs. Am J Physiol Regul Integr Comp Physiol 244: R74-R77, 1983.
34. Singh R, Denton K, Bertram J, Jefferies A, Head G, Lombardo P, Schneider-Kolsky M, Moritz K. Development of cardiovascular disease due to renal insufficiency in male sheep following fetal unilateral nephrectomy. J Hypertens 27: 386-396, 2009.
35. Singh R, Denton K, Jefferies A, Bertram J, Moritz K. Reduced nephron endowment due to fetal uninephrectomy impairs renal sodium handling in male sheep. Clin Sci (Lond) 118: 669-680, 2010.
36. Singh R, Moritz K, Wintour E, Jefferies A, Iqbal J, Bertram J, Denton K. Fetal uninephrectomy in male sheep alters the systemic and renal responses to angiotensin II infusion and AT1R blockade. Am J Physiol Renal Physiol 301: F319-F326, 2011.
37. Singh RR, Cullen-McEwen LA, Kett MM, Boon WM, Dowling J, Bertram JF, Moritz KM. Prenatal corticosterone exposure results in altered AT1/AT2, nephron deficit and hypertension in the rat offspring. J Physiol 579: 503-513, 2007.
38. Stefano AD, Wittner M, Corman B. Vasopressin stimulation of NaCl transport in the medullary thick ascending limb of Henle's loop is decreased in aging mice. Pflügers Arch 419: 327-331, 1991.
39. Teitelbaum I, McGuinness S. Vasopressin resistance in chronic renal failure: Evidence for the role of decreased V2 receptor mRNA. J Clin Invest 96: 378-385, 1995.
40. Terwel D, Haaf JT, Markerink M, Jolles J. Changes in plasma vasopressin concentration and plasma osmolality in relation to age and time of day in the male Wistar rat. Acta Endocrinol 126: 357-362, 1992.
41. Tian Y, Serino R, Verbalis J. Downregulation of renal vasopressin V2 receptor and aquaporin-2 expression parallels age-associated defects in urine concentration. Am J Physiol Renal Physiol 287: F797-F805, 2004.
42. Vize P, Seufert D, Carroll T, Wallingford J. Model systems for the study of kidney develpment: analysis of organ induction and patterning. Dev Biol 188: 189-204, 1997.
43. Wintour E, Moritz K, Johnson K, Ricardo S, Samuel C, Dodic M. Reduced nephron number in adult sheep, hypertensive as a result of prenatal glucocorticoid treatment. J Physiol 549: 929-935, 2003.
44. Wlodek M, Mibus A, Tan A, Siebel A, Owens J, Moritz K. Normal lactational environment restores nephron endowment and prevents hypertension after placental restriction in the rat. J Am Soc Nephrol 18: 1688-1696, 2007.
45. Woods LL, Ingelfinger JR, Nyengaard JR, Rasch R. Maternal protein restriction suppresses the newborn renin-angiotensin system and programs adult hypertension in rats. Pediatr Res 49: 460-467, 2001.
46. Woods LL, Weeks DA. Naturally occurring intrauterine growth retardation and adult blood pressure in rats. Pediatr Res 56: 763-767, 2004.
47. Woods LL, Weeks DA, Rasch R. Programming of adult blood pressure by maternal protein restriction: role of nephrogenesis. Kidney Int 65: 1339-1348, 2004.