The effect of inappropriate therapy on bacteremia by ESBL-producing bacteria

Infection

Volumn 39, Issue 6, 2011, Pages 555-561

  De Rosa, F G ^a   Pagani, N ^a   Fossati, L ^b   Raviolo, S ^a   Cometto, C ^a   Cavallerio, P ^b   Parlato, C ^b   Guglielmi, E ^b   Serra, R ^b   Di Perri, G ^a  

^a UNIVERSITY OF TURIN   (Italy)

^b MOLINETTE HOSPITAL   (Italy)

Author keywords

Bacteremia; Charlson score; ESBL; Mortality

Indexed keywords

AMIKACIN; AMOXICILLIN PLUS CLAVULANIC ACID; AZTREONAM; CARBAPENEM; CEFEPIME; CEFOTAXIME; CEFOXITIN; CEFPODOXIME; CEFTAZIDIME; CEFTRIAXONE; CIPROFLOXACIN; CLAVULANIC ACID; COTRIMOXAZOLE; EXTENDED SPECTRUM BETA LACTAMASE; GENTAMICIN; IMIPENEM; LEVOFLOXACIN; MEROPENEM; PIPERACILLIN PLUS TAZOBACTAM; TOBRAMYCIN;

ADULT; ANTIBIOTIC SENSITIVITY; ARTICLE; BLOOD CULTURE; CONTROLLED STUDY; ESCHERICHIA COLI; FEMALE; GRAM NEGATIVE SEPSIS; HUMAN; IN VITRO STUDY; INAPPROPRIATE PRESCRIBING; KLEBSIELLA PNEUMONIAE; MAJOR CLINICAL STUDY; MALE; MINIMUM INHIBITORY CONCENTRATION; MORTALITY; PROTEUS MIRABILIS; RETROSPECTIVE STUDY; RISK FACTOR; SEPTIC SHOCK; UNIVARIATE ANALYSIS;

ADULT; AGED; AGED, 80 AND OVER; ANTI-BACTERIAL AGENTS; BACTEREMIA; BETA-LACTAMASES; ENTEROBACTERIACEAE INFECTIONS; ESCHERICHIA COLI; FEMALE; HUMANS; KLEBSIELLA PNEUMONIAE; MALE; MIDDLE AGED; PROTEUS MIRABILIS; RETROSPECTIVE STUDIES; SURVIVAL ANALYSIS; TREATMENT FAILURE; TREATMENT OUTCOME;

EID: 82655184153     PISSN: 03008126     EISSN: 14390973     Source Type: Journal    
DOI: 10.1007/s15010-011-0201-x     Document Type: Article

References (17)

1. JDD Pitout KB Laupland 2008 Extended-spectrum beta-lactamase-producing enterobacteriaceae: an emerging public-health concern Lancet Infect Dis 8 159 166 18291338 10.1016/S1473-3099(08)70041-0 1:CAS:528:DC%2BD1cXjsl2gsbg%3D (Pubitemid 351249250)
2. S Meier R Weber R Zbinden C Ruef B Hasse 2011 Extended-spectrum beta-lactamase-producing Gram-negative pathogens in community-acquired urinary tract infections: an increasing challenge for antimicrobial therapy Infection 39 333 340 21706226 10.1007/s15010-011-0132-6 1:CAS:528:DC%2BC3MXhtFehs7zE (epub 2011 Jun 25)
3. F Gona ML Mezzatesta D Corona D Zerbo V Scriffignano S Stefani P Veroux M Veroux 2011 Klebsiella pneumoniae ESBL producers responsible for severe UTIs in a renal transplant unit Infection 39 83 85 21264678 10.1007/s15010-011-0081-0 1:STN:280:DC%2BC3M3hsVantQ%3D%3D (epub 2011 Jan 25) PMID: 21264678
4. SP Kuster B Hasse V Huebner V Bansal R Zbinden C Ruef B Ledergerber R Weber 2010 Risks factors for infections with extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae at a tertiary care university hospital in Switzerland Infection 38 33 40 20108162 10.1007/s15010-009-9207-z 1:CAS:528:DC%2BC3cXit1OlsLY%3D (epub 2010 Jan 27) PMID: 20108162
5. C Gudiol L Calatayud C Garcia-Vidal J Lora-Tamayo M Cisnal R Duarte M Arnan M Marin J Carratala F Gudiol 2010 Bacteraemia due to extended-spectrum beta-lactamase-producing Escherichia coli (ESBL-EC) in cancer patients: clinical features, risk factors, molecular epidemiology and outcome J Antimicrob Chemother 65 333 341 19959544 10.1093/jac/dkp411 1:CAS:528:DC%2BC3cXhtVSqt7k%3D
6. DL Paterson WC Ko A Von Gottberg S Mohapatra JM Casellas H Goossens L Mulazimoglu G Trenholme KP Klugman RA Bonomo LB Rice MM Wagener JG McCormack VL Yu 2004 Antibiotic therapy for Klebsiella pneumoniae bacteremia: implications of production of extended-spectrum beta-lactamases Clin Infect Dis 39 31 37 15206050 10.1086/420816 1:CAS:528:DC%2BD2cXmtlSgtr4%3D (Pubitemid 38879546)
7. M Tumbarello M Sanguinetti E Montuori EM Trecarichi B Posteraro B Fiori R Citton T D'Inzeo G Fadda R Cauda T Spanu 2007 Predictors of mortality in patients with bloodstream infections caused by extended-spectrum-beta-lactamase- producing enterobacteriaceae: importance of inadequate initial antimicrobial treatment Antimicrob Agents Chemother 51 1987 1994 17387156 10.1128/AAC.01509-06 1:CAS:528:DC%2BD2sXmtlKrsrY%3D (Pubitemid 46903084)
8. K Cohen-Nahum L Saidel-Odes K Riesenberg F Schlaeffer A Borer 2010 Urinary tract infections caused by multi-drug resistant Proteus mirabilis: risk factors and clinical outcomes Infection 38 41 46 19998053 10.1007/s15010-009- 8460-5 1:STN:280:DC%2BC3c7itVelsQ%3D%3D (epub 2009 Dec 7) PMID: 19998053
9. J Rodriguez-Bano MD Navarro L Romero MA Muniain M de Cueto MJ Rios JR Hernandez A Pascual 2006 Bacteremia due to extended-spectrum beta-lactamase producing Escherichia coli in the CTX-M era: a new clinical challenge Clin Infect Dis 43 1407 1414 17083012 10.1086/508877 (Pubitemid 44845640)
10. M Ortega F Marco A Soriano M Almela JA Martinez A Munoz J Mensa 2009 Analysis of 4,758 Escherichia coli bacteraemia episodes: predictive factors for isolation of an antibiotic-resistant strain and their impact on the outcome J Antimicrob Chemother 63 568 574 19126669 10.1093/jac/dkn514 1:CAS:528: DC%2BD1MXitVSitrw%3D
11. Joo EJ, Kang CI, Ha YE, Park SY, Kang SJ, Wi YM, Lee NY, Chung DR, Peck KR, Song JH. Impact of inappropriate empiric antimicrobial therapy on outcome in Pseudomonas aeruginosa bacteraemia: a stratified analysis according to sites of infection. Infection. 2011;39:309-18.
12. ME Charlson P Pompei KL Ales CR MacKenzie 1987 A new method of classifying prognostic comorbidity in longitudinal studies: development and validation J Chronic Dis 40 373 383 3558716 10.1016/0021-9681(87)90171-8 1:STN:280:DyaL2s7ms1GnsQ%3D%3D (Pubitemid 17055592)
13. M Venditti M Falcone S Corrao G Licata P Serra 2009 Outcomes of patients hospitalized with community-acquired, health care-associated, and hospital-acquired pneumonia Ann Intern Med 150 19 19124816 W5
14. CI Kang SH Kim WB Park KD Lee HB Kim EC Kim MD Oh KW Choe 2004 Bloodstream infections due to extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae: risk factors for mortality and treatment outcome, with special emphasis on antimicrobial therapy Antimicrob Agents Chemother 48 4574 4581 15561828 10.1128/AAC.48.12.4574-4581.2004 1:CAS:528:DC%2BD2cXhtVKmtrnM (Pubitemid 39577656)
15. A Kola O Maciejewski D Sohr S Ziesing P Gastmeier 2007 Clinical impact of infections caused by ESBL-producing E coli and K pneumoniae Scand J Infect Dis 39 975 982 17852950 10.1080/00365540701466140 (Pubitemid 350153868)
16. VL Yu 2011 Guidelines for hospital-acquired pneumonia and health-care-associated pneumonia: a vulnerability, a pitfall, and a fatal flaw Lancet Infect Dis 11 248 252 21371658 10.1016/S1473-3099(11)70005-6
17. Tascini C, Malacarne P, Langer M, Menichetti F, Rossolini GM The 2011 revolution in antimicrobial susceptibility testing and reporting: what the ICU physicians need to know. Minerva Anestesiol. 2011. [Epub ahead of print].