Combination of withaferin A and X-ray irradiation enhances apoptosis in U937 cells

Toxicology in Vitro

Volumn 25, Issue 8, 2011, Pages 1803-1810

  Yang, Eun Sun ^a   Choi, Min Jung ^a   Kim, Jin Hee ^a   Choi, Kyeong Sook ^b   Kwon, Taeg Kyu ^a  

^a Keimyung University   (South Korea)

^b Ajou University School of Medicine   (South Korea)

Author keywords

Apoptosis; Bcl 2; Radiation; Reactive oxygen species; Withaferin A

Indexed keywords

ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; CASPASE 3; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38 INHIBITOR; PROTEIN BCL 2; PROTEIN PARP; REACTIVE OXYGEN METABOLITE; SB 203589; SB 600125; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG; WITHAFERIN A;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL STRAIN U937; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFICACY; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME REGULATION; HUMAN; HUMAN CELL; IONIZING RADIATION; LYMPHOMA CELL; PROTEIN CLEAVAGE; PROTEIN FUNCTION; RADIOSENSITIZATION; TREATMENT RESPONSE;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; COMBINED MODALITY THERAPY; DOWN-REGULATION; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LYMPHOMA, LARGE B-CELL, DIFFUSE; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTO-ONCOGENE PROTEINS C-BCL-2; REACTIVE OXYGEN SPECIES; U937 CELLS; WITHANOLIDES; X-RAY THERAPY;

WITHANIA SOMNIFERA;

EID: 82655172914     PISSN: 08872333     EISSN: 18793177     Source Type: Journal    
DOI: 10.1016/j.tiv.2011.09.016     Document Type: Article

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