Propofol inhibits the activation of p38 through up-regulating the expression of Annexin A1 to exert its anti-inflammation effect

PLoS ONE

Volumn 6, Issue 12, 2011, Pages

  Tang, Jing ^a   Chen, Xi ^b   Tu, Weifeng ^b   Guo, Yuanbo ^a   Zhao, Zhenlong ^a   Xue, Qiong ^a   Lin, Chunshui ^a   Xiao, Jinfang ^a   Sun, Xuegang ^a   Tao, Tao ^a   Gu, Miaoning ^a   Liu, Youtan ^c  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

^b GUANGZHOU GENERAL HOSPITAL OF GUANGZHOU MILITARY COMMAND   (China)

^c THE UNIVERSITY OF HONG KONG SHENZHEN HOSPITAL   (China)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOCORTIN 1; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE P38 INHIBITOR; PROPOFOL; TUMOR NECROSIS FACTOR ALPHA; ANTIINFLAMMATORY AGENT; INTRAVENOUS ANESTHETIC AGENT; MITOGEN ACTIVATED PROTEIN KINASE P38; PRIMER DNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG MECHANISM; ENDOTOXEMIA; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE SILENCING; HUMAN; HUMAN CELL; IN VITRO STUDY; MALE; MASS SPECTROMETRY; MOLECULAR MECHANICS; MONONUCLEAR CELL; NONHUMAN; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS INHIBITION; RAT; TWO DIMENSIONAL ELECTROPHORESIS; UPREGULATION; WESTERN BLOTTING; ANIMAL; BIOSYNTHESIS; BLOOD; CYTOLOGY; GENE EXPRESSION REGULATION; LEUKOCYTE; METABOLISM; METHODOLOGY; MONOCYTE; PHOSPHORYLATION; TWO DIMENSIONAL GEL ELECTROPHORESIS;

ANESTHETICS, INTRAVENOUS; ANIMALS; ANNEXIN A1; ANTI-INFLAMMATORY AGENTS; DNA PRIMERS; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION REGULATION; HUMANS; INTERLEUKIN-1BETA; INTERLEUKIN-6; LEUKOCYTES; LIPOPOLYSACCHARIDES; MONOCYTES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROPOFOL; RATS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

EID: 82555185587     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0027890     Document Type: Article

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