Adverse metabolic effects of a hypercaloric, high-fat diet in rodents precede observable changes in body weight

Nutrition Research

Volumn 31, Issue 9, 2011, Pages 707-714

  McDonald, Sarah D ^a   Pesarchuk, Eric ^a   Don Wauchope, Andrew ^a   El Zimaity, Hala ^b,c   Holloway, Alison C ^a  

^a MCMASTER UNIVERSITY   (Canada)

^b HAMILTON REGIONAL LABORATORY MEDICINE PROGRAM   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

Author keywords

Abdominal fat; Animal; Dietary fats; Immunohistochemistry; Metabolic diseases; Models; Nonalcoholic fatty liver disease; Obesity

Indexed keywords

GLUCAGON LIKE PEPTIDE 1; GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CALORIC INTAKE; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; FEMALE; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE TEST; HYPERGLYCEMIA; HYPERINSULINEMIA; INTRAABDOMINAL FAT; LIPID DIET; METABOLIC DISORDER; NONALCOHOLIC FATTY LIVER; NONHUMAN; OBESITY; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; RAT; TRIACYLGLYCEROL BLOOD LEVEL; WEIGHT CHANGE; WEIGHT GAIN;

ADIPOSITY; ANIMALS; BLOOD GLUCOSE; BODY WEIGHT; DIET, HIGH-FAT; DIETARY FATS; DISEASE MODELS, ANIMAL; FATTY LIVER; GLUCAGON-LIKE PEPTIDE 1; GLUCOSE TOLERANCE TEST; GLYCEMIC INDEX; HYPERGLYCEMIA; HYPERINSULINISM; INSULIN; INTRA-ABDOMINAL FAT; MALE; OBESITY; RATS; RATS, WISTAR; TRIGLYCERIDES;

EID: 82555168914     PISSN: 02715317     EISSN: 18790739     Source Type: Journal    
DOI: 10.1016/j.nutres.2011.08.009     Document Type: Article

References (36)

1. Pereira-Lancha L.O., Coelho D.F., de Campos-Ferraz P.L., Lancha A.H. Body fat regulation: is it a result of a simple energy balance or a high fat intake?. J Am Coll Nutr 2010, 29(4):343-351.
2. Garriguet D. Overview of Canadians' Eating habits. Cat. No. 82-620-MIE, 1-43. 2004. Ottawa, Canada, Statistics Canada. Nutrition: Findings from the Canadian Community Health Survey.
3. McDonald S.D. Management and prevention of obesity in adults and children. CMAJ 2007, 176(8):1109-1110.
4. Sinaiko A. Obesity, insulin resistance and the metabolic syndrome. J Pediatr (Rio J) 2007, 83(1):3-4.
5. Sinaiko A.R., Donahue R.P., Jacobs D.R., Prineas R.J. Relation of weight and rate of increase in weight during childhood and adolescence to body size, blood pressure, fasting insulin, and lipids in young adults. The Minneapolis Children's Blood Pressure Study. Circulation 1999, 99(11):1471-1476.
6. Barker D.J., Osmond C., Forsen T.J., Kajantie E., Eriksson J.G. Trajectories of growth among children who have coronary events as adults. N Engl J Med 2005, 353(17):1802-1809.
7. Seaman C.E.A., Bower J., Fleming M. Nutrition knowledge and lunchtime eating habits of secondary school children in Lothian. J Consum Stud Home Econ 1997, 21:259-269.
8. Srinivasan K., Viswanad B., Asrat L., Kaul C.L., Ramarao P. Combination of high-fat diet-fed and low-dose streptozotocin-reated rat: a model for type 2 diabetes and pharmacological screening. Pharmacol Res 2005, 52(4):313-320.
9. Kang M., Oh J.W., Lee H.K., Chung H.S., Lee S.M., Kim C., et al. Anti-obesity effect of PM-F2-OB, an anti-obesity herbal formulation, on rats fed a high-fat diet. Biol Pharm Bull 2004, 27(8):1251-1256.
10. Zhang F., Ye C., Li G., Ding W., Zhou W., Zhu H., et al. The rat model of type 2 diabetic mellitus and its glycometabolism characters. Exp Anim 2003, 52(5):401-407.
11. Ferezou-Viala J., Roy A.F., Serougne C., Gripois D., Parquet M., Bailleux V., et al. Long-term consequences of maternal high-fat feeding on hypothalamic leptin sensitivity and diet-induced obesity in the offspring. Am J Physiol Regul Integr Comp Physiol 2007, 293(3):R1056-R1062.
12. Buettner R., Parhofer K.G., Woenckhaus M., Wrede C.E., Kunz-Schughart L.A., Scholmerich J., et al. Defining high-fat-diet rat models: metabolic and molecular effects of different fat types. J Mol Endocrinol 2006, 36(3):485-501.
13. Iossa S., Lionetti L., Mollica M.P., Crescenzo R., Botta M., Barletta A., et al. Effect of high-fat feeding on metabolic efficiency and mitochondrial oxidative capacity in adult rats. Br J Nutr 2003, 90(5):953-960.
14. Zhao H.L., Sims J.S., Shim S.H., Ha Y.W., Kang S.S., Kim Y.S. Antiobese and hypolipidemic effects of platycodin saponins in diet-induced obese rats: evidences for lipase inhibition and calorie intake restriction. Int J Obes 2005, 29:983-990.
15. Han L.K., Zheng Y.N., Yoshikawa M., Okuda H., Kimura Y. Anti-obesity effects of chikusetsusaponins isolated from Panax japonicus rhizomes. BMC Complement Altern Med 2005, 5:9.
16. Aprahamian C.J., Tekant G., Chen M., Yagmurlu A., Yang Y.K., Loux T., et al. A rat model of childhood diet-induced obesity: Roux-en-Y gastric bypass induced changes in metabolic parameters and gastric peptide ghrelin. Pediatr Surg Int 2007, 23(7):653-657.
17. Maurer A.D., Chen Q., McPherson C., Reimer R.A. Changes in satiety hormones and expression of genes involved in glucose and lipid metabolism in rats weaned onto diets high in fibre or protein reflect susceptibility to increased fat mass in adulthood. J Physiol 2009, 587(Pt 3):679-691.
18. Holloway A.C., Cuu D.Q., Morrison K.M., Gerstein H.C., Tarnopolsky M.A. Transgenerational effects of fetal and neonatal exposure to nicotine. Endocrine 2007, 31(3):254-259.
19. Bruin J.E., Kellenberger L.D., Gerstein H.C., Morrison K.M., Holloway A.C. Fetal and neonatal nicotine exposure and postnatal glucose homeostasis: identifying critical windows of exposure. J Endocrinol 2007, 194(1):171-178.
20. Burt A.D., Mutton A., Day C.P. Diagnosis and interpretation of steatosis and steatohepatitis. Semin Diagn Pathol 1998, 15(4):246-258.
21. Jung R.T. Obesity as a disease. [Review] [50 refs]. Br Med Bull 1997, 53(2):307-321.
22. Carmen R. Connolly Consulting Inc. Interventions related to obesity: a State of the Evidence Review. 1-28. 2005. Heart and Stroke Foundation of Canada.
23. Buettner R., Scholmerich J., Bollheimer L.C. High-fat diets: modeling the metabolic disorders of human obesity in rodents. Obesity (Silver Spring) 2007, 15(4):798-808.
24. Iossa S., Lionetti L., Mollica M.P., Barletta A., Liverini G. Energy intake and utilization vary during development in rats. J Nutr 1999, 129(8):1593-1596.
25. Judge M.K., Zhang J., Tumer N., Carter C., Daniels M.J., Scarpace P.J. Prolonged hyperphagia with high-fat feeding contributes to exacerbated weight gain in rats with adult-onset obesity. Am J Physiol Regul Integr Comp Physiol 2008, 295(3):R773-R780.
26. Hansotia T., Maida A., Flock G., Yamada Y., Tsukiyama K., Seino Y., et al. Extrapancreatic incretin receptors modulate glucose homeostasis, body weight, and energy expenditure. J Clin Invest 2007, 117(1):143-152.
27. Reinehr T., de S.G., Roth C.L. Fasting glucagon-like peptide-1 and its relation to insulin in obese children before and after weight loss. J Pediatr Gastroenterol Nutr 2007, 44(5):608-612.
28. Doyle M.E., Egan J.M. Glucagon-like peptide-1. Recent Prog Horm Res 2001, 56:377-399.
29. Erickson S.K. Nonalcoholic fatty liver disease (NAFLD). J Lipid Res 2008.
30. Manco M., Bottazzo G., DeVito R., Marcellini M., Mingrone G., Nobili V. Nonalcoholic fatty liver disease in children. J Am Coll Nutr 2008, 27(6):667-676.
31. Fu J.H., Sun H.S., Wang Y., Zheng W.Q., Shi Z.Y., Wang Q.J. The effects of a fat- and sugar-enriched diet and chronic stress on nonalcoholic fatty liver disease in male Wistar rats. Dig Dis Sci 2009.
32. Yeh M.M., Brunt E.M. Pathology of nonalcoholic fatty liver disease. Am J Clin Pathol 2007, 128(5):837-847.
33. Xu Z.J., Fan J.G., Ding X.D., Qiao L., Wang G.L. Characterization of high-fat, diet-induced, non-alcoholic steatohepatitis with fibrosis in rats. Dig Dis Sci 2009.
34. Carter-Kent C., Yerian L.M., Brunt E.M., Angulo P., Kohli R., Ling S.C., et al. Nonalcoholic steatohepatitis in children: a multicenter clinicopathological study. Hepatology 2009, 50(4):1113-1120.
35. Tschop M., Heiman M.L. Rodent obesity models: an overview. Exp Clin Endocrinol Diabetes 2001, 109(6):307-319.
36. Archer Z.A., Mercer J.G. Brain responses to obesogenic diets and diet-induced obesity. Proc Nutr Soc 2007, 66(1):124-130.