The chromophore structure of the long-lived intermediate of the C128T channelrhodopsin-2 variant

FEBS Letters

Volumn 585, Issue 24, 2011, Pages 3998-4001

  Bruun, Sara ^a,b   Naumann, Hendrik ^a   Kuhlmann, Uwe ^a   Schulz, Claudia ^a   Stehfest, Katja ^b   Hegemann, Peter ^b   Hildebrandt, Peter ^a  

^a TECHNISCHE UNIVERSITÄT BERLIN   (Germany)

^b HUMBOLDT UNIVERSITY   (Germany)

Author keywords

Bacteriorhodopsin; Channelrhodopsin; Photocycle; Resonance Raman; Retinal; Retroretinal

Indexed keywords

BACTERIORHODOPSIN; RETINAL; RHODOPSIN;

ABSORPTION SPECTROSCOPY; ARTICLE; CHROMATOPHORE; CONTROLLED STUDY; HUMAN; HUMAN CELL; HYDROLYSIS; LIGHT ABSORPTION; PRIORITY JOURNAL; RAMAN SPECTROMETRY; RETINA;

COLOR; HUMANS; HYDROGEN-ION CONCENTRATION; MUTANT PROTEINS; MUTATION; NERVE TISSUE PROTEINS; RHODOPSIN; SPECTROPHOTOMETRY, ULTRAVIOLET; SPECTRUM ANALYSIS, RAMAN;

EID: 82555168188     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2011.11.007     Document Type: Article

References (27)

1. G. Nagel, T. Szellas, W. Huhn, S. Kateriya, N. Adeishvili, P. Berthold, D. Ollig, P. Hegemann, and E. Bamberg Channelrhodopsin-2, a directly light-gated cation-selective membrane channel Proc. Natl. Acad. Sci. USA 100 2003 13940 13945 (Pubitemid 37499170)
2. G. Nagel, T. Szellas, S. Kateriya, N. Adeishvili, P. Hegemann, and E. Bamberg Channelrhodopsins: directly light-gated cation channels Biochem. Soc. Trans. 33 2005 863 866 (Pubitemid 41160880)
3. E.S. Boyden, F. Zhang, E. Bamberg, G. Nagel, and K. Deisseroth Millisecond-timescale, genetically targeted optical control of neural activity Nat. Neurosci. 8 2005 1263 1268 (Pubitemid 43348147)
4. F. Zhang, L.P. Wang, M. Brauner, J.F. Liewald, K. Kay, N. Watzke, P.G. Wood, E. Bamberg, G. Nagel, A. Gottschalk, and K. Deisseroth Multimodal fast optical interrogation of neural circuitry Nature 446 2007 633 639 (Pubitemid 46606891)
5. P.S. Lagali, D. Balya, G.B. Awatramani, T.A. Munch, D.S. Kim, V. Busskamp, C.L. Cepko, and B. Roska Light-activated channels targeted to ON bipolar cells restore visual function in retinal degeneration Nat. Neurosci. 6 2008 667 675 (Pubitemid 351748114)
6. A. Berndt, O. Yizhar, L.A. Gunaydin, P. Hegemann, and K. Deisseroth Bi-stable neural state switches Nat. Neurosci. 2 2009 229 234
7. M. Nack, I. Radu, M. Gossing, C. Bamann, E. Bamberg, G.F. von Mollard, and J. Heberle The DC gate in channelrhodopsin-2: crucial hydrogen bonding interaction between C128 and D156 Photochem. Photobiol. Sci. 9 2010 194 198
8. I. Radu, C. Bamann, M. Nack, G. Nagel, E. Bamberg, and J. Heberle Conformational changes of channelrhodopsin-2 J. Am. Chem. Soc. 131 2009 7313 7319
9. C. Bamann, R. Gueta, S. Kleinlogel, G. Nagel, and E. Bamberg Structural guidance of the photocycle of channelrhodopsin-2 by an interhelical hydrogen bond Biochemistry 49 2010 267 278
10. K. Stehfest, E. Ritter, A. Berndt, F. Bartl, and P. Hegemann The branched photocycle of the slow-cycling channelrhodopsin-2 mutant C128T J. Mol. Biol. 398 2010 690 702
11. E. Ritter, K. Stehfest, A. Berndt, P. Hegemann, and F.J. Bartl Monitoring light-induced structural changes of channelrhodopsin-2 by UV-visible and Fourier transform infrared spectroscopy J. Biol. Chem. 283 2008 35033 35041
12. M.K. Verhoefen, C. Bamann, R. Blocher, U. Forster, E. Bamberg, and J. Wachtveitl The photocycle of channelrhodopsin-2: ultrafast reaction dynamics and subsequent reaction steps ChemPhysChem 11 2010 3113 3122
13. J. Peters, R. Peters, and W. Stoeckenius A photosensitive product of sodium borohydride reduction of bacteriorhodopsin FEBS Lett. 61 1976 128 134
14. T. Schreckenbach, B. Walckhoff, and D. Oesterhelt Studies on retinal-protein interaction in bacteriorhodopsin Eur. J. Biochem. 76 1977 499 511
15. C. Bamann, T. Kirsch, G. Nagel, and E. Bamberg Spectral characteristics of the photocycle of channelrhodopsin-2 and its implication for channel function J. Mol. Biol. 375 2008 686 694 (Pubitemid 350297289)
16. D. Oesterhelt, and W. Stoeckenius Functions of a new photoreceptor membrane Proc. Natl. Acad. Sci. USA 70 1973 2853 2857
17. H. Naumann, D.H. Murgida, M. Engelhard, J.P. Klare, and P. Hildebrandt Time-resolved resonance Raman spectroscopy of sensory rhodopsin II in the micro- and millisecond time range using gated cw excitation J. Raman Spectrosc. 37 2006 436 441
18. O.P. Ernst, P.A. Sánches Murcia, P. Daldrop, S. Tsunoda, S. Kateriya, and P. Hegemann Photoactivation of channelrhodopsin J. Biol. Chem. 283 2008 1637 1643
19. T. Althaus, W. Eisfeld, R. Lohrmann, and M. Stockburger Application of Raman spectroscopy to retinal proteins Isr. J. Chem. 35 1995 227 251
20. B. Curry, I. Palings, A. Broek, J. Pardoen, J. Lugtenburg, and R. Mathies Vibrational analysis of the retinal isomers Advances in Infrared and Raman Spectroscpy vol. 12 1985 Wiley Heyden New York 115 178 (Chapter 3)
21. N. Tschirner, M. Schenderlein, K. Brose, E. Schlodder, M.A. Mroginski, C. Thomsen, and P. Hildebrandt Resonance Raman spectra of beta-carotene in solution and in photosystems revisited: an experimental and theoretical study Phys. Chem. Chem. Phys. 11 2009 11471 11478
22. M.E. Heyde, D. Gill, R.G. Kilponen, and L. Rimai Raman spectra of Schiff bases of retinal (models of visual photoreceptors) J. Am. Chem. Soc. 93 1971 6776 6780
23. K. Vogt, and K. Kirschfeld Chemical identity of the chromophore of fly visual pigment Naturwissenschaften 71 1984 211 213
24. D.G. Stavenga On visual pigment templates and the spectral shape of invertebrate rhodopsins and metarhodopsins J. Comp. Physiol. A 196 2010 869 878
25. T. Schreckenbach, B. Walckhoff, and D. Oesterhelt Specificity of the retinal binding site of bacteriorhodopsin: chemical and stereochemical requirements for the binding of retinol and retinal Biochemistry 17 1978 5353 5359
26. T.G. Kusakabe, N. Takimoto, M. Jin, and M. Tsuda Evolution and the origin of the visual retinoid cycle in vertebrates Phil. Trans. R. Soc. B 364 2009 2897 2910
27. P.W. Hildebrand, P. Scheerer, J.H. Park, H.W. Choe, R. Piechnick, O.P. Ernst, K.P. Hofmann, and M. Heck A ligand channel through the G protein coupled receptor opsin PLoS One 4 2009 e4382