Subcutaneous thrombotic vasculopathy syndrome: An ominous condition reminiscent of calciphylaxis: Calciphylaxis sine calcifications?

American Journal of Dermatopathology

Volumn 33, Issue 8, 2011, Pages 796-802

  Zembowicz, Artur ^a,b   Navarro, Paula ^a,c   Walters, Stephanie ^d   Lyle, Stephen R ^c,d   Moschella, Samuel L ^a   Miller, Danielle ^a  

^a LAHEY HOSPITAL AND MEDICAL CENTER   (United States)

^b DermatopathologyConsultations LLC   (United States)

^c TUFTS MEDICAL CENTER   (United States)

^d UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

Calciphylaxis; Skin ulcer; Thrombotic vasculopathy

Indexed keywords

CALCIUM ION; CREATININE; IMMUNOGLOBULIN G ANTIBODY; WARFARIN;

ADULT; AGED; ARTICLE; CASE REPORT; CELLULITIS; FEMALE; HISTOPATHOLOGIC SKIN REACTION; HUMAN; MALE; PATHOLOGY; PRIORITY JOURNAL; PURPURA; SEPSIS; SKIN BIOPSY; SKIN BLOOD VESSEL DISORDER; SKIN CALCIFICATION; SKIN NECROSIS; SKIN ULCER; SUBCUTANEOUS NODULE; SUBCUTANEOUS THROMBOTIC VASCULOPATHY SYNDROME; UREA NITROGEN BLOOD LEVEL; WEIGHT REDUCTION;

AGED; AGED, 80 AND OVER; ARTERIOLES; BIOPSY; CALCIPHYLAXIS; CAPILLARIES; FATAL OUTCOME; FEMALE; HUMANS; ISCHEMIA; MALE; MIDDLE AGED; NECROSIS; PREDICTIVE VALUE OF TESTS; PROGNOSIS; SKIN ULCER; SUBCUTANEOUS TISSUE; THROMBOSIS;

EID: 82455199302     PISSN: 01931091     EISSN: 15330311     Source Type: Journal    
DOI: 10.1097/DAD.0b013e31820edb81     Document Type: Article

References (18)

1. Asobie N, Wong E, Cook MG, et al. Calciphylaxis in a diabetic patient provoked by warfarin therapy. Clin Exp Dermatol. 2008;33:342-344. (Pubitemid 351550625)
2. Goldsmith DJ, Goldsmith DJ. Calciphylaxis, thrombotic diathesis and defects in coagulation regulation. Nephrol Dial Transplant. 1997;12: 1082-1083. (Pubitemid 27216350)
3. Goli AK, Goli SA, Shah LS, et al. Calciphylaxis: A rare association with alcoholic cirrhosis. Are deficiencies in protein C and S the cause? South Med J. 2005;98:736-739. (Pubitemid 41061663)
4. Rostaing L, el Feki S, Delisle MB, et al. Calciphylaxis in a chronic hemodialysis patient with protein S deficiency. Am J Nephrol. 1995;15: 524-527.
5. Rudwaleit M, Schwarz A, Trautmann C, et al. Severe calciphylaxis in a renal patient on long-term oral anticoagulant therapy. Am J Nephrol. 1996;16:344-348. (Pubitemid 26143586)
6. Wong JJ, Laumann A, Martinez M, et al. Calciphylaxis and antiphospholipid antibody syndrome. J Am Acad Dermatol. 2000;42:849.
7. Weenig RH, Sewell LD, Davis MD, et al. Calciphylaxis: Natural history, risk factor analysis, and outcome. J Am Acad Dermatol. 2007;56: 569-579. (Pubitemid 46400180)
8. Selye H. Calciphylaxis. Chicago, IL: Chicago University Press; 1962.
9. Kalajian AH, Malhotra PS, Callen JP, et al. Calciphylaxis with normal renal and parathyroid function: Not as rare as previously believed. Arch Dermatol. 2009;145:451-458.
10. Nigwekar SU, Wolf M, Sterns RH, et al. Calciphylaxis from nonuremic causes: A systematic review. Review. Clin J Am Soc Nephrol. 2008;3: 1139-1143.
11. Swanson AM, Desai SR, Jackson JD, et al. Calciphylaxis associated with chronic inflammatory conditions, immunosuppression therapy, and normal renal function: A report of 2 cases. Arch Dermatol. 2009;145:723-725.
12. Ortiz A, Ceccato F, Roverano S, et al. Calciphylaxis associated with rheumatoid arthritis: Communication of the second case. Clin Rheumatol. 2009;28(Suppl 1):S65-S68.
13. Almafragi A, Vandorpe J, Dujardin K, et al. Calciphylaxis in a cardiac patient without renal disease. Acta Cardiol. 2009;64:91-93.
14. Mehta RL, Scott G, Sloand JA, et al. Skin necrosis associated with acquired protein C deficiency in patients with renal failure and calciphylaxis. Am J Med. 1990;88:252-257. (Pubitemid 20100371)
15. Anderson DC, Stewart WK, Piercy DM, et al. Calcifying panniculitis with fat and skin necrosis in a case of uraemia with autonomous hyperparathyroidism. Lancet. 1968;2:323-325.
16. Coates T, Kirkland GS, Dymock RB, et al. Cutaneous necrosis from calcific uremic arteriolopathy. Review. Am J Kidney Dis. 1998;32:384-391. (Pubitemid 28411210)
17. Bleyer AJ, White WL, Choi MJ, et al. Calcific small vessel ischemic disease (calciphylaxis) in dialysis patients. Review. Int J Artif Organs. 2000;23:351-355. (Pubitemid 30461886)
18. Weenig RH, Weenig RH. Pathogenesis of calciphylaxis: Hans Selye to nuclear factor kappa-B. Review. J Am Acad Dermatol. 2008;58: 458-471.