Popliteal node visualization during standard pedal lymphoscintigraphy for a swollen limb indicates impaired lymph drainage

American Journal of Roentgenology

Volumn 197, Issue 6, 2011, Pages 1443-1448

  Burnand, Katherine M ^a   Glass, Daphne M ^b   Sundaraiya, Sumati ^a   Mortimer, Peter S ^c   Peters, A Michael ^a,b  

^a ROYAL SUSSEX COUNTY HOSPITAL   (United Kingdom)

^b Harley Street Clinic ^*  (United Kingdom)

^c ST GEORGE S HOSPITAL   (United Kingdom)

Author keywords

99mTc nanocolloid; Lipedema; Lymph nodes; Lymphedema; Lymphoscintigraphy; Popliteal nodes

Indexed keywords

NANOCOLL TC 99M;

ADOLESCENT; ADULT; AGED; ARTICLE; CHILD; CLINICAL EXAMINATION; FEMALE; HUMAN; IMAGE ANALYSIS; LIMB SWELLING; LYMPH NODE; LYMPHATIC DRAINAGE IMPAIRMENT; LYMPHATIC SYSTEM DISEASE; LYMPHEDEMA; LYMPHOSCINTIGRAPHY; MAJOR CLINICAL STUDY; MALE; POPLITEAL NODE; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SCHOOL CHILD;

ADOLESCENT; ADULT; AGED; CHI-SQUARE DISTRIBUTION; CHILD; FEMALE; HUMANS; LEG; LYMPHEDEMA; LYMPHOSCINTIGRAPHY; MALE; MIDDLE AGED; RADIOPHARMACEUTICALS; TECHNETIUM TC 99M AGGREGATED ALBUMIN;

EID: 82455194922     PISSN: 0361803X     EISSN: 15463141     Source Type: Journal    
DOI: 10.2214/AJR.11.6631     Document Type: Article

References (21)

1. Mortimer PS, Levick JR. Chronic peripheral oedema: the critical role of the lymphatic system. Clin Med 2004; 4:448-453 (Pubitemid 39457274)
2. Kerchner K, Fleischer A, Yosipovitch G. Lower extremity lymphedema. J Am Acad Dermatol 2008; 59:324-331
3. Mellor RH, Hubert CE, Stanton AWB, et al. Lymphatic dysfunction not aplasia underlies Milroy disease. Microcirculation 2010; 17:281-296
4. Mellor RH, Tate N, Stanton AWB, et al. Mutations in FOXC2 in humans (lymphoedema distichiasis syndrome) cause lymphatic dysfunction on dependency. J Vasc Res 2011; 48:397-407
5. Uren RF, Howman-Giles R, Thompson JF, et al. Interval nodes: the forgotten sentinel nodes in patients with melanoma. Arch Surg 2000; 135:1168-1172
6. Roozendaal GK, de Vries JD, van Poll D, et al. Sentinel nodes outside lymph node basin in patients with primary cutaneous melanoma. Br J Surg 2001; 88:305-308 (Pubitemid 32142724)
7. Sumner WE, Ross MI, Mansfield PF, et al. Implications of lymphatic drainage to unusual sentinel nodes sites in patients with primary cutaneous melanoma. Cancer 2002; 95:354-360 (Pubitemid 34787602)
8. McMasters KM, Chao C, Wong SL, et al.; Sunbelt Melanoma Trial Group. Interval sentinel lymph nodes in melanoma. Arch Surg 2002; 137:543-547; discussion, 547-549
9. Weissleder H, Weissleder R. Lymphedema: evaluation of qualitative and quantitative lymphoscintigraphy in 238 patients. Radiology 1988; 167:729-735
10. Mortimer PS. Managing lymphedema. Clin Dermatol 1995; 13:499-505 (Pubitemid 26073920)
11. Ely JW, Osheroff JA, Chambliss ML, Ebell MH. Approach to leg edema of unclear etiology. J Am Board Fam Med 2006; 19:148-160 (Pubitemid 44046977)
12. Tiwari A, Cheng K, Button M, Myint F, Hamilton G. Differential diagnosis, investigation, and current treatment of lower limb lymphedema. Arch Surg 2003; 138:152-161 (Pubitemid 36216279)
13. Altman DG. Practical statistics for medical research. London, UK: Chapman and Hall, 1991
14. Browse NL, Burnand K, Mortimer PS. The normal lymphographic appearances of the lower limb and pelvis. In: Kinmonth JB, ed. The lymphatics. London, UK: Edward Arnold, 1982:19-35
15. Hatta N, Morita R, Yamada M, Takehara K, Ichiyanagi K, Yokoyama K. Implications of popliteal node detected by sentinel lymph node biopsy. Dermatol Surg 2005; 31:327-330 (Pubitemid 43072989)
16. Thompson JF, Hunt JA, Culjak G, Uren RF, Howman- Giles R, Harman CR. Popliteal lymph node metastasis from primary cutaneous melanoma. Eur J Surg Oncol 2000; 26:172-176 (Pubitemid 30242942)
17. Szuba A, Shin WS, Strauss HW, Rockson S. The third circulation: radionuclide lymphoscintigraphy in the evaluation of lymphedema. J Nucl Med 2003; 44:43-57 (Pubitemid 36077712)
18. Bräutigam P, Földi E, Schaiper I, Krause T, Vanscheidt W, Moser E. Analysis of lymphatic drainage in various forms of leg edema using two compartment lymphoscintigraphy. Lymphology 1998; 31:43-55 (Pubitemid 28308996)
19. Burnand KM, Glass DM, Mortimer PS, Peters AM. Lymphatic dysfunction in the apparently clinically normal contralateral limbs of patients with unilateral lower limb swelling. Clin Nucl Med (in press)
20. Schunemann H, Willich N. Lymphoedema of the arm after primary treatment of breast cancer. Anticancer Res 1998; 18:2235-2236 (Pubitemid 28386497)
21. Stanton AW, Modi S, Bennett Britton TM, et al. Lymphatic drainage in the muscle and subcutis of the arm after breast cancer treatment. Breast Cancer Res Treat 2009; 117:549-557