Do rare variant genotypes predict common variant genotypes?

BMC Proceedings

Volumn 5, Issue SUPPL. 9, 2011, Pages

  Kent Jr , Jack W ^a   Farook, Vidya ^a   Göring, Harald H H ^a   Dyer, Thomas D ^a   Almasy, Laura ^a   Duggirala, Ravindranath ^a   Blangero, John ^a  

^a SOUTHWEST FOUNDATION FOR BIOMEDICAL RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CONFERENCE PAPER; EXOME; GENE LINKAGE DISEQUILIBRIUM; GENETIC ANALYSIS; GENETIC VARIABILITY; GENOTYPE; HUMAN; PREDICTIVE VALUE; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM;

EID: 82455194213     PISSN: None     EISSN: 17536561     Source Type: Journal    
DOI: 10.1186/1753-6561-5-S9-S87     Document Type: Conference Paper

References (9)

1. The new genetics: global views of biology. Lander E, Science 1996 274 536 539 10.1126/science.274.5287.536 8928008 (Pubitemid 26360427)
2. Population genetics: making sense out of sequence. Chakravarti A, Nat Genet 1999 21 56 60 9915503 (Pubitemid 29031494)
3. Personal genomes: the case of the missing heritability. Maher B, Nature 2008 456 18 21 18987709
4. Finding the missing heritability of complex diseases. Manolio TA, Collins FS, Cox NJ, Goldstein DB, Hindorff LA, Hunter DJ, McCarthy MI, Ramos EM, Cardon LR, Chakravarti A, et al. Nature 2009 461 747 753 10.1038/nature08494 19812666
5. Rare variants create synthetic genome-wide associations. Dickson SP, Wang K, Krantz I, Hokonarson H, Goldstein DB, PLoS Biol 2010 8 1000294 10.1371/journal.pbio.1000294 20126254
6. Genetic Analysis Workshop 17 mini-exome simulation. Almasy L, Dyer TD, Peralta JM, Kent JW Jr., Charlesworth JC, Curran JE, Blangero J, BMC Proc 2011 5 suppl 9 2 21810212
7. Multipoint quantitative-trait linkage analysis in general pedigrees. Almasy L, Blangero J, Am J Hum Genet 1998 62 1198 1211 10.1086/301844 9545414 (Pubitemid 28199022)
8. A comparison of collapsing methods for the statistical analysis of rare variants. Dering C, Ziegler A, König IR, Hemmelmann C, BMC Proc 2011 5 Suppl 9 115
9. Capability of common SNPs to tag rare variants. Sun X, Namkung J, Zhu X, Elston RC, BMC Proc 2011 5 Suppl 9 88