Short-term exposure to nickel alters the adult rat brain antioxidant status and the activities of crucial membrane-bound enzymes: Neuroprotection by L-cysteine

Biological Trace Element Research

Volumn 143, Issue 3, 2011, Pages 1673-1681

  Liapi, Charis ^a   Zarros, Apostolos ^a   Theocharis, Stamatios ^a   Voumvourakis, Konstantinos ^b   Anifantaki, Foteini ^a   Gkrouzman, Elena ^a   Mellios, Zois ^a   Skandali, Nikolina ^a   Al Humadi, Hussam ^a   Tsakiris, Stylianos ^a  

^a UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

^b NATIONAL AND KAPODISTRIAN UNIVERSITY OF ATHENS   (Greece)

Author keywords

Acetylcholinesterase; Antioxidant status; L cysteine; Mg 2+ ATPase; Na +,K + ATPase; Nickel chloride; Rat brain

Indexed keywords

ACETYLCHOLINESTERASE; ADENOSINE TRIPHOSPHATASE (MAGNESIUM); ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ANTIOXIDANT; CYSTEINE; NICKEL CHLORIDE; SODIUM CHLORIDE;

ADULT ANIMAL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN LEVEL; BRAIN METABOLISM; BRAIN TISSUE; CONTROLLED STUDY; DECAPITATION; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME INHIBITION; IN VIVO STUDY; MALE; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; RAT; SHORT COURSE THERAPY; SPECTROPHOTOMETRY; TREATMENT DURATION;

ACETYLCHOLINESTERASE; ANIMALS; ANTIOXIDANTS; BRAIN; CA(2+) MG(2+)-ATPASE; CYSTEINE; MALE; NEUROPROTECTIVE AGENTS; NICKEL; RATS; RATS, WISTAR; SODIUM-POTASSIUM-EXCHANGING ATPASE;

RATTUS; RATTUS NORVEGICUS;

EID: 82455192296     PISSN: 01634984     EISSN: 15590720     Source Type: Journal    
DOI: 10.1007/s12011-011-9006-0     Document Type: Article

References (46)

1. E Obone SK Chakrabarti C Bai MA Malick L Lamontagne KS Subramanian 1999 Toxicity and bioaccumulation of nickel sulphate in Sprague-Dawley rats following 13 weeks of subchronic exposure J Toxicol Environ Health A 57 379 401 10478821 10.1080/009841099157593 1:CAS:528:DyaK1MXks1ahtb4%3D (Pubitemid 29368884)
2. A Zawisza-Raszka B Dolezych 2008 Acetylcholinesterase, catalase and glutathione S-transferase activity in beet armyworm (Spodoptera exigua) exposed to nickel and/or diazinon Acta Biol Hung 59 31 45 18401943 10.1556/ABiol.59. 2008.1.3 (Pubitemid 351324716)
3. Goyer RA (1986) Toxic effects of metals. In: Klaassen CD, Amdur MO, Doull J (eds) Casarett and Doull's Toxicology: The Basic Science of Poisons. MacMillan, New York, pp 623-680
4. JE Evans ML Miller A Andringa L Hastings 1995 Behavioral, histological, and neurochemical effects of nickel (II) on the rat olfactory system Toxicol Appl Pharmacol 130 209 220 7871534 10.1006/taap.1995.1026 1:CAS:528: DyaK2MXjvFCntbg%3D
5. TP Coogan DM Latta ET Snow M Costa 1989 Toxicity and carcinogenicity of nickel compounds Crit Rev Toxicol 19 341 384 2663022 10.3109/10408448909029327 1:CAS:528:DyaL1MXksFWksbk%3D (Pubitemid 19148662)
6. A Furst 1984 Mechanism of action of nickel as a carcinogen: needed information IARC Sci Publ 53 245 252 6398284 1:CAS:528:DyaL2MXkvVaksbk%3D
7. M Costa MP Abbracchio J Simmons-Hansen 1981 Factors influencing the phagocytosis, neoplastic transformation, and cytotoxicity of particulate nickel compounds in tissue culture systems Toxicol Appl Pharmacol 60 313 323 7281191 10.1016/0041-008X(91)90234-6 1:CAS:528:DyaL3MXlsVCqsbc%3D (Pubitemid 11060823)
8. JM Benson RL Carpenter FF Hahn PJ Haley RL Hanson CH Hobbs JA Pickrell JK Dunnick 1987 Comparative inhalation toxicity of nickel subsulfide to F344/N rats and B6C3F1 mice exposed for 12 days Fundam Appl Toxicol 9 251 265 3653567 10.1016/0272-0590(87)90047-9 1:CAS:528:DyaL2sXlsVyrsLw%3D
9. JM Benson DG Burt RL Carpenter AF Eidson FF Hahn PJ Haley RL Hanson CH Hobbs JA Pickrell JK Dunnick 1988 Comparative inhalation toxicity of nickel sulfate to F344/N rats and B6C3F1 mice exposed for twelve days Fundam Appl Toxicol 10 164 178 3350225 10.1016/0272-0590(88)90261-8 1:CAS:528: DyaL1cXht1Kis7w%3D (Pubitemid 18089732)
10. FW Sunderman Jr. 2001 Nasal toxicity, carcinogenicity, and olfactory uptake of metals Ann Clin Lab Sci 31 3 24 11314863 1:CAS:528: DC%2BD3MXnvF2lug%3D%3D
11. RG Adams N Crabtree 1961 Anosmia in alkaline battery workers Br J Ind Med 18 216 221 13681418 1:CAS:528:DyaF38XlsV2rsA%3D%3D
12. J Henriksson J Tallkvist H Tjälve 1997 Uptake of nickel into the brain via olfactory neurons in rats Toxicol Lett 91 153 162 9175852 10.1016/S0378-4274(97)03885-X 1:CAS:528:DyaK2sXjvF2ms7o%3D (Pubitemid 27214567)
13. J Tallkvist J Henriksson R d'Argy H Tjälve 1998 Transport and subcellular distribution of nickel in the olfactory system of pikes and rats Toxicol Sci 43 196 203 9710961 10.1093/toxsci/43.2.196 1:CAS:528: DyaK1cXltVKktrk%3D (Pubitemid 28363393)
14. Z Shi 1994 Nickel carbonyl: toxicity and human health Sci Total Environ 148 293 298 8029705 10.1016/0048-9697(94)90406-5 1:CAS:528:DyaK2cXks1Cms7s%3D (Pubitemid 24165575)
15. H Kita W Van der Kloot 1973 Action of Co and Ni at the frog neuromuscular junction Nat New Biol 245 52 53 4517046 10.1038/245052a0 1:CAS:528: DyaE2cXjsVWnsA%3D%3D
16. S Fatehyab M Hasan MZ Hasan J Anwar 1980 Effect of nickel on the levels of dopamine, noradrenaline and serotonin in different regions of the rat brain Acta Pharmacol Toxicol Copenh 47 318 320 7468231 1:STN:280:DyaL3M7jtVSltg%3D%3D (Pubitemid 10025524)
17. + action on acetylcholinesterase activity in correlation with spontaneous quantal release of acetylcholine in rat diaphragm Jpn J Physiol 39 429 440 2552204 10.2170/jjphysiol.39.429 1:CAS:528:DyaL1MXlvVOns7c%3D (Pubitemid 19230524)
18. DF Bogdanski A Tissari BB Brodie 1968 Role of sodium, potassium, ouabain and reserpine in uptake, storage and metabolism of biogenic amines in synaptosomes Life Sci 7 419 428 5652184 10.1016/0024-3205(68)90013-1 1:STN:280:DyaF1c3ntVGjug%3D%3D
19. J Hernandez 1987 Brain Na+, K + -ATPase activity possibly regulated by a specific serotonin receptor Brain Res 408 399 402 3036307 10.1016/0006-8993(87) 90414-8 1:STN:280:DyaL2s3ktlGhsQ%3D%3D (Pubitemid 17068470)
20. GJ Lees A Lehmann M Sandberg A Hamberger 1990 The neurotoxicity of ouabain, a sodium-potassium ATPase inhibitor, in the rat hippocampus Neurosci Lett 120 159 162 1705675 10.1016/0304-3940(90)90027-7 1:CAS:528: DyaK3MXhtlGktb0%3D
21. M Mata DJ Fink H Gainer CB Smith L Davidsen H Savaki WJ Schwartz L Sokoloff 1980 Activity-dependent energy metabolism in rat posterior pituitary primarily reflects sodium pump activity J Neurochem 34 213 215 7452237 10.1111/j.1471-4159.1980.tb04643.x 1:CAS:528:DyaL3cXktVCltbY%3D (Pubitemid 10172700)
22. BS Sastry JW Phillis 1977 Antagonism of biogenic amine-induced depression of cerebral cortical neurones by Na+, K + -ATPase in inhibitors Can J Physiol Pharmacol 55 170 179 141320 10.1139/y77-025 1:CAS:528:DyaE2sXlslOlt74%3D (Pubitemid 8119142)
23. AC Swann 1984 (Na+, K+)-adenosine triphosphatase regulation by the sympathetic nervous system: effects of noradrenergic stimulation and lesion in vivo J Pharmacol Exp Ther 228 304 311 6141282 1:CAS:528:DyaL2cXhtleisLs%3D (Pubitemid 14190734)
24. Sanui H, Rubin H (1982) The role of magnesium in cell proliferation and transformation. In: Boynton AL, McKochan WL, Whitfield JP (eds) Ions, Cell Proliferation and Cancer. Academic Press, New York, pp 517-537
25. H Carageorgiou V Tzotzes C Pantos C Mourouzis A Zarros S Tsakiris 2004 In vivo and in vitro effects of cadmium on adult rat brain total antioxidant status, acetylcholinesterase, (Na+, K+)-ATPase and Mg2 + -ATPase activities: protection by L-cysteine Basic Clin Pharmacol Toxicol 94 112 118 15049340 10.1111/j.1742-7843.2004.pto940303.x 1:CAS:528:DC%2BD2cXis1alt7c%3D (Pubitemid 38419849)
26. L Patrick 2003 Toxic metals and antioxidants: Part II. The role of antioxidants in arsenic and cadmium toxicity Altern Med Rev 8 106 128 12777158 (Pubitemid 36676180)
27. EEC Council 1986 EEC Council Directive 86/609/EEC of 24 November 1986 on the approximation of laws, regulations and administrative provisions of the Member States regarding the protection of animals used for experimental and other scientific purposes Off J Eur Union L358 1 28
28. 2 in mice and rats Zhongguo Yao Li Xue Bao 19 80 84 10375767 1:CAS:528:DyaK1cXmslWhsQ%3D%3D
29. S Tsakiris 2001 Effects of L-phenylalanine on acetylcholinesterase and Na+, K + -ATPase activities in adult and aged rat brain Mech Ageing Dev 122 491 501 11292514 10.1016/S0047-6374(01)00217-2 1:CAS:528:DC%2BD3MXisVWhu7w%3D (Pubitemid 32276011)
30. S Tsakiris P Angelogianni KH Schulpis P Behrakis 2000 Protective effect of L-cysteine and glutathione on rat brain Na+, K + -ATPase inhibition induced by free radicals Z Naturforsch C 55 271 277 10817219 1:CAS:528: DC%2BD3cXivFygsbw%3D (Pubitemid 30254804)
31. OH Lowry NJ Rosebrough AL Farr RJ Randall 1951 Protein measurement with the Folin phenol reagent J Biol Chem 193 265 275 14907713 1:CAS:528: DyaG38XhsVyrsw%3D%3D
32. H Carageorgiou A Zarros S Tsakiris 2003 Selegiline long-term effects on brain acetylcholinesterase, (Na+, K+)-ATPase activities, antioxidant status and learning performance of aged rats Pharmacol Res 48 245 251 12860442 10.1016/S1043-6618(03)00149-X 1:CAS:528:DC%2BD3sXltl2gsrw%3D (Pubitemid 36818931)
33. H Carageorgiou C Pantos A Zarros I Mourouzis D Varonos D Cokkinos S Tsakiris 2005 Changes in antioxidant status, protein concentration, acetylcholinesterase, (Na+, K+)- and Mg2 + -ATPase activities in the brain of hyper- and hypothyroid adult rats Metab Brain Dis 20 129 139 15938131 10.1007/s11011-005-4150-x 1:CAS:528:DC%2BD2MXksVWrs7o%3D (Pubitemid 40768489)
34. GL Ellman KD Courtney V Andres Jr. RM Featherstone 1961 A new and rapid colorimetric determination of acetylcholinesterase activity Biochem Pharmacol 7 88 95 13726518 10.1016/0006-2952(61)90145-9 1:CAS:528:DyaF3MXht1Gns7o%3D
35. K Bowler R Tirri 1974 The temperature characteristics of synaptic membrane ATPases from immature and adult rat brain J Neurochem 23 611 613 4279007 10.1111/j.1471-4159.1974.tb06068.x 1:CAS:528:DyaE2MXlsFSisw%3D%3D
36. S Kawanishi S Inoue K Yamamoto 1994 Active oxygen species in DNA damage induced by carcinogenic metal compounds Environ Health Perspect 102 17 20 7843093 1:CAS:528:DyaK2cXmvFCrs70%3D (Pubitemid 24316351)
37. EL Novelli NL Rodrigues BO Ribas 1995 Superoxide radical and toxicity of environmental nickel exposure Hum Exp Toxicol 14 248 251 7779454 10.1177/096032719501400303 1:CAS:528:DyaK2MXls1ers7c%3D
38. H Carageorgiou V Tzotzes A Sideris A Zarros S Tsakiris 2005 Cadmium effects on brain acetylcholinesterase activity and antioxidant status of adult rats: modulation by zinc, calcium and L-cysteine co-administration Basic Clin Pharmacol Toxicol 97 320 324 16236145 10.1111/j.1742-7843.2005.pto-174.x 1:CAS:528:DC%2BD2MXht1altrzP (Pubitemid 41608126)
39. C Liapi A Zarros P Galanopoulou S Theocharis N Skandali H Al-Humadi F Anifantaki E Gkrouzman Z Mellios S Tsakiris 2008 Effects of short-term exposure to manganese on the adult rat brain antioxidant status and the activities of acetylcholinesterase, (Na+, K+)-ATPase and Mg2 + -ATPase: modulation by L-cysteine Basic Clin Pharmacol Toxicol 103 171 175 18816301 10.1111/j.1742-7843.2008.00281.x 1:CAS:528:DC%2BD1cXpslWgsr8%3D (Pubitemid 352019730)
40. C Liapi A Zarros S Theocharis H Al-Humadi F Anifantaki E Gkrouzman Z Mellios N Skandali S Tsakiris 2009 The neuroprotective role of L-cysteine towards the effects of short-term exposure to lanthanum on the adult rat brain antioxidant status and the activities of acetylcholinesterase, (Na+, K+)- and Mg2 + -ATPase Biometals 22 329 335 18937033 10.1007/s10534-008-9169-0 1:CAS:528:DC%2BD1MXjsFyktrc%3D
41. MF Frasco D Fournier F Carvalho L Guilhermino 2005 Do metals inhibit acetylcholinesterase (AChE)? Implementation of assay conditions for the use of AChE activity as a biomarker of metal toxicity Biomarkers 10 360 375 16243721 10.1080/13547500500264660 1:CAS:528:DC%2BD2MXhtFCjtrbK (Pubitemid 41701226)
42. H Miszta Z Dabrowski Z Szyguła K Spodaryk 1986 The effect of intrarenal nickel subsulfide injections upon the activity of selected erythrocyte and bone marrow enzymes in rats Acta Pharmacol Toxicol Copenh 59 425 429 3811970 10.1111/j.1600-0773.1986.tb00194.x 1:CAS:528:DyaL2sXksFegsg%3D%3D (Pubitemid 17176257)
43. S Bag T Vora R Ghatak I Nilufer D D'mello J Pereira C Cutinho V Rao 1999 A study of toxic effects of heavy metal contaminants from sludge-supplemented diets on male Wistar rats Ecotoxicol Environ Saf 42 163 170 10051366 10.1006/eesa.1998.1736 1:CAS:528:DyaK1MXhsVels78%3D (Pubitemid 29130037)
44. C Tsangaris E Papathanasiou E Cotou 2007 Assessment of the impact of heavy metal pollution from a ferro-nickel smelting plant using biomarkers Ecotoxicol Environ Saf 66 232 243 16753214 10.1016/j.ecoenv.2006.03.011 1:CAS:528:DC%2BD28Xht1KltL3E (Pubitemid 44830079)
45. G Repetto A del Peso P Sanz M Repetto 2001 In vitro effects of lithium and nickel at different levels on Neuro-2a mouse neuroblastoma cells Toxicol In Vitro 15 363 368 11566564 10.1016/S0887-2333(01)00037-6 1:CAS:528: DC%2BD3MXmvVyisbk%3D (Pubitemid 32889659)
46. RK Asthana SP Singh RK Singh 1992 Nickel effects on phosphate uptake, alkaline phosphatase, and ATPase of a cyanobacterium Bull Environ Contam Toxicol 48 45 54 1533803 10.1007/BF00197482 1:CAS:528:DyaK38Xms1Ojsw%3D%3D