Epidemiology and antifungal susceptibility of bloodstream fungal isolates in pediatric patients: A Spanish multicenter prospective survey

Journal of Clinical Microbiology

Volumn 49, Issue 12, 2011, Pages 4158-4163

  Pemán, Javier ^a   Cantón, Emilia ^a   Linares Sicilia, María José ^b   Roselló, Eva María ^c   Borrell, Nuria ^d   Ruiz Pérez de Pipaon, María Teresa ^e   Guinea, Jesús ^f   García, Julio ^g   Porras, Aurelio ^h   García Tapia, Ana María ⁱ   Pérez del Molino, Luisa ^j   Suárez, Anabel ^k   Alcoba, Julia ^l   García García, Inmaculada ^m  

^a HOSPITAL UNIVERSITARIO LA FE   (Spain)

^b HOSPITAL UNIVERSITARIO REINA SOFÍA   (Spain)

^c HOSPITAL UNIVERSITARI VALL D HEBRON   (Spain)

^d HOSPITAL UNIVERSITARIO SON ESPASES   (Spain)

^e HOSPITAL UNIVERSITARIO VIRGEN DEL ROCÍO   (Spain)

^f HOSPITAL GENERAL UNIVERSITARIO GREGORIO MARAÑÓN   (Spain)

^g HOSPITAL UNIVERSITARIO LA PAZ   (Spain)

^h HOSPITAL REGIONAL UNIVERSITARIO DE MÁLAGA   (Spain)

ⁱ HOSPITAL UNIVERSITARIO PUERTA DEL MAR   (Spain)

^j HOSPITAL CLÍNICO UNIVERSITARIO   (Spain)

^k HOSPITAL UNIVERSITARIO VIRGEN MACARENA   (Spain)

^l HOSPITAL UNIVERSITARIO NUESTRA SEÑORA DE CANDELARIA   (Spain)

^m HOSPITAL UNIVERSITARIO DE SALAMANCA   (Spain)

more..

Author keywords

[No Author keywords available]

Indexed keywords

AMPHOTERICIN B; ANIDULAFUNGIN; CASPOFUNGIN; ECHINOCANDIN; FLUCONAZOLE; FLUCYTOSINE; ITRACONAZOLE; MICAFUNGIN; POSACONAZOLE; VORICONAZOLE;

ADOLESCENT; ANTIFUNGAL RESISTANCE; ANTIFUNGAL SUSCEPTIBILITY; ARTICLE; BLOOD CULTURE; BROTH DILUTION; CANDIDA; CANDIDA ALBICANS; CANDIDA FAMATA; CANDIDA GLABRATA; CANDIDA KRUSEI; CANDIDA PARAPSILOSIS; CANDIDA TROPICALIS; CANDIDEMIA; CHILD; CLAVISPORA LUSITANIAE; COLORIMETRY; CONTROLLED STUDY; DESCRIPTIVE RESEARCH; FEMALE; FUNGUS CULTURE; FUNGUS IDENTIFICATION; FUNGUS ISOLATION; HEALTH SURVEY; HOSPITAL PATIENT; HUMAN; IN VITRO STUDY; INFANT; INTENSIVE CARE UNIT; INTRAVASCULAR CATHETER; MAJOR CLINICAL STUDY; MALE; MINIMUM INHIBITORY CONCENTRATION; MULTIDRUG RESISTANCE; NEUTROPENIA; NEWBORN; NONHUMAN; PICHIA GUILLIERMONDII; POPULATION RESEARCH; PREMATURITY; PRESCHOOL CHILD; PRIORITY JOURNAL; PROSPECTIVE STUDY; REFERENCE VALUE; RHODOTORULA GLUTINIS; RISK FACTOR; SCHOOL CHILD; SPAIN; SPECIES DIFFERENCE; SURGICAL TECHNIQUE; TRICHOSPORON ASAHII; WARD;

ADOLESCENT; ANTIFUNGAL AGENTS; CHILD; CHILD, PRESCHOOL; DRUG RESISTANCE, FUNGAL; FEMALE; FUNGEMIA; FUNGI; HUMANS; INFANT; INFANT, NEWBORN; MALE; MICROBIAL SENSITIVITY TESTS; PREVALENCE; PROSPECTIVE STUDIES; SPAIN;

EID: 82455186866     PISSN: 00951137     EISSN: 1098660X     Source Type: Journal    
DOI: 10.1128/JCM.05474-11     Document Type: Article

References (26)

1. Almirante, B., et al. 2006. Epidemiology, risk factors, and prognosis of Candida parapsilosis bloodstream infections: case-control population-based surveillance study of patients in Barcelona, Spain, from 2002 to 2003. J. Clin. Microbiol. 44:1681-1685. (Pubitemid 43726255)
2. Arendrup, M. C., et al. 2011. National surveillance of fungemia in Denmark (2004 to 2009). J. Clin. Microbiol. 49:325-334.
3. Blyth, C. C., et al. 2009. Not just little adults: candidemia epidemiology, molecular characterization, and antifungal susceptibility in neonatal and pediatric patients. Pediatrics 123:1360-1368.
4. Clinical and Laboratory Standards Institute. 2008. Reference method for broth dilution antifungal susceptibility testing of yeasts, approved standard. CLSI document M27-A3. Clinical and Laboratory Standards Institute, Wayne, PA.
5. Clinical and Laboratory Standards Institute. 2011. Minutes of the Subcommittee on Antifungal Susceptibility Testing meeting, Atlanta, GA. Clinical and Laboratory Standards Institute, Wayne, PA.
6. Hachem, R., H. Hanna, D. Kontoyiannis, Y. Jiang, and I. Raad. 2008. The changing epidemiology of invasive candidiasis: Candida glabrata and Candida krusei as the leading causes of candidemia in hematologic malignancy. Cancer 112:2493-2499.
7. Maertens, J., et al. 2010. European guidelines for antifungal management in leukemia and hematopoietic stem cell transplant recipients: summary of the ECIL 3-2009 update. Bone Marrow Transplant. 46:709-718.
8. Neofytos, D., et al. 2010. Epidemiology and outcome of invasive fungal infections in solid organ transplant recipients. Transpl. Infect. Dis. 12:220-229.
9. Neofytos, D., et al. 2009. Epidemiology and outcome of invasive fungal infection in adult hematopoietic stem cell transplant recipients: analysis of Multicenter Prospective Antifungal Therapy (PATH) Alliance registry. Clin. Infect. Dis. 48:265-273.
10. Neu, N., et al. 2009. Epidemiology of candidemia at a children's hospital, 2002 to 2006. Pediatr. Infect. Dis. J. 28:806-809.
11. Pappas, P. G., et al. 2009. Clinical practice guidelines for the management of candidiasis: 2009 update by the Infectious Diseases Society of America. Clin. Infect. Dis. 48:503-535.
12. Pappas, P. G., et al. 2003. A prospective observational study of candidemia: epidemiology, therapy, and influences on mortality in hospitalized adult and pediatric patients. Clin. Infect. Dis. 37:634-643. (Pubitemid 37100802)
13. Pemán, J., et al. 2011. Variación de la epidemiologia de las fungemias y de la sensibilidad a fluconazol de los aislamientos en los últimos 10 años en España: resultados del estudio FUNGEMYCA. Rev. Iberoam. Micol. 28:91-99.
14. Pemán, J., E. Cantón, and M. Gobernado. 2005. Epidemiology and antifungal susceptibility of Candida species isolated from blood: results of a 2-year multicentre study in Spain. Eur. J. Clin. Microbiol. Infect. Dis. 24:23-30. (Pubitemid 40179128)
15. Pfaller, M. A., et al. 2011. Clinical breakpoints for voriconazole and Candida spp. revisited: review of microbiologic, molecular, pharmacodynamic, and clinical data as they pertain to the development of species-specific interpretive criteria. Diagn. Microbiol. Infect. Dis. 70:330-343.
16. Pfaller, M. A., D. Andes, D. J. Diekema, A. Espinel-Ingroff, and D. Sheehan. 2010. Wild-type MIC distributions, epidemiological cutoff values and species-specific clinical breakpoints for fluconazole and Candida: time for harmonization of CLSI and EUCAST broth microdilution methods. Drug Resist. Updat. 13:180-195.
17. Pfaller, M. A., and D. J. Diekema. 2007. Epidemiology of invasive candidiasis: a persistent public health problem. Clin. Microbiol. Rev. 20:133-163. (Pubitemid 46167771)
18. Pfaller, M. A., and D. J. Diekema. 2010. Epidemiology of invasive mycoses in North America. Crit. Rev. Microbiol. 36:1-53.
19. Pfaller, M. A., et al. 2011. Clinical breakpoints for the echinocandins and Candida revisited: integration of molecular, clinical, and microbiological data to arrive at species-specific interpretative criteria. Drug Resist. Updat. 14:164-176.
20. Pfaller, M. A., et al. 2008. Geographic and temporal trends in isolation and antifungal susceptibility of Candida parapsilosis: a global assessment from the ARTEMIS DISK Antifungal Surveillance Program, 2001 to 2005. J. Clin. Microbiol. 46:842-849. (Pubitemid 351379967)
21. Pfaller, M. A., G. J. Moet, S. A. Messer, R. N. Jones, and M. Castanheira. 2011. Geographic variations in species distribution and echinocandin and azole antifungal resistance rates among Candida bloodstream infection isolates: report from the SENTRY antimicrobial surveillance program (2008 to 2009). J. Clin. Microbiol. 49:396-399.
22. Singhi, S. C., T. C. Reddy, and A. Chakrabarti. 2004. Candidemia in a pediatric intensive care unit. Pediatr. Crit. Care Med. 5:369-374.
23. Stamos, J. K., and A. H. Rowley. 1995. Candidemia in a pediatric population. Clin. Infect. Dis. 20:571-575.
24. Tortorano, A. M., et al. 2004. Epidemiology of candidaemia in Europe: results of a 28-month European Confederation of Medical Mycology (ECMM) hospital-based surveillance study. Eur. J. Clin. Microbiol. Infect. Dis. 23:317-322. (Pubitemid 38669942)
25. Wisplinghoff, H., et al. 2004. Nosocomial bloodstream infections in US hospitals: analysis of 24,179 cases from a prospective nationwide surveillance study. Clin. Infect. Dis. 39:309-317. (Pubitemid 39050477)
26. Zaoutis, T. E., H. M. Greves, E. Lautenbach, W. B. Bilker, and S. E. Coffin. 2004. Risk factors for disseminated candidiasis in children with candidemia. Pediatr. Infect. Dis. J. 23:635-641. (Pubitemid 38924888)