-
1
-
-
34250020201
-
Hepatocellular carcinoma: epidemiology and molecular carcinogenesis
-
El-Serag HB, Rudolph KL. Hepatocellular carcinoma: epidemiology and molecular carcinogenesis. Gastroenterology 2007; 132: 2557-2576.
-
(2007)
Gastroenterology
, vol.132
, pp. 2557-2576
-
-
El-Serag, H.B.1
Rudolph, K.L.2
-
3
-
-
77349092851
-
Molecular classification and novel targets in hepatocellular carcinoma: recent advancements
-
Hoshida Y, Toffanin S, Lachenmayer A, Villanueva A, Minguez B, Llovet JM. Molecular classification and novel targets in hepatocellular carcinoma: recent advancements. Semin Liver Dis 2010; 30: 35-51.
-
(2010)
Semin Liver Dis
, vol.30
, pp. 35-51
-
-
Hoshida, Y.1
Toffanin, S.2
Lachenmayer, A.3
Villanueva, A.4
Minguez, B.5
Llovet, J.M.6
-
6
-
-
77955051048
-
Role of histone acetylation in cell physiology and diseases: An update
-
Khan SN, Khan AU. Role of histone acetylation in cell physiology and diseases: An update. Clin Chim Acta 2010; 411: 1401-1411.
-
(2010)
Clin Chim Acta
, vol.411
, pp. 1401-1411
-
-
Khan, S.N.1
Khan, A.U.2
-
7
-
-
34547890019
-
Functions of site-specific histone acetylation and deacetylation
-
Shahbazian MD, Grunstein M. Functions of site-specific histone acetylation and deacetylation. Annu Rev Biochem 2007; 76: 75-100.
-
(2007)
Annu Rev Biochem
, vol.76
, pp. 75-100
-
-
Shahbazian, M.D.1
Grunstein, M.2
-
8
-
-
57749170458
-
The many roles of histone deacetylases in development and physiology: implications for disease and therapy
-
Haberland M, Montgomery RL, Olson EN. The many roles of histone deacetylases in development and physiology: implications for disease and therapy. Nat Rev Genet 2009; 10: 32-42.
-
(2009)
Nat Rev Genet
, vol.10
, pp. 32-42
-
-
Haberland, M.1
Montgomery, R.L.2
Olson, E.N.3
-
9
-
-
58149378600
-
The structure and function of histone deacetylases: the target for anti-cancer therapy
-
Zhang Y, Fang H, Jiao J, Xu W. The structure and function of histone deacetylases: the target for anti-cancer therapy. Curr Med Chem 2008; 15: 2840-2849.
-
(2008)
Curr Med Chem
, vol.15
, pp. 2840-2849
-
-
Zhang, Y.1
Fang, H.2
Jiao, J.3
Xu, W.4
-
11
-
-
35848936696
-
Overexpression of myocyte enhancer factor 2 and histone hyperacetylation in hepatocellular carcinoma
-
Bai X, Wu L, Liang T, Liu Z, Li J, Li D, et al. Overexpression of myocyte enhancer factor 2 and histone hyperacetylation in hepatocellular carcinoma. J Cancer Res Clin Oncol 2008; 134: 83-91.
-
(2008)
J Cancer Res Clin Oncol
, vol.134
, pp. 83-91
-
-
Bai, X.1
Wu, L.2
Liang, T.3
Liu, Z.4
Li, J.5
Li, D.6
-
12
-
-
77951491943
-
miR-17-5p Promotes migration of human hepatocellular carcinoma cells through the p38 mitogen-activated protein kinase-heat shock protein 27 pathway
-
Yang F, Yin Y, Wang F, Wang Y, Zhang L, Tang Y, et al. miR-17-5p Promotes migration of human hepatocellular carcinoma cells through the p38 mitogen-activated protein kinase-heat shock protein 27 pathway. Hepatology 2010; 51: 1614-1623.
-
(2010)
Hepatology
, vol.51
, pp. 1614-1623
-
-
Yang, F.1
Yin, Y.2
Wang, F.3
Wang, Y.4
Zhang, L.5
Tang, Y.6
-
13
-
-
0347444723
-
MicroRNAs: genomics, biogenesis, mechanism, and function
-
Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004; 116: 281-297.
-
(2004)
Cell
, vol.116
, pp. 281-297
-
-
Bartel, D.P.1
-
14
-
-
3042767202
-
MicroRNAs: small RNAs with a big role in gene regulation
-
He L, Hannon GJ. MicroRNAs: small RNAs with a big role in gene regulation. Nat Rev Genet 2004; 5: 522-531.
-
(2004)
Nat Rev Genet
, vol.5
, pp. 522-531
-
-
He, L.1
Hannon, G.J.2
-
15
-
-
61449558376
-
Effect of trichostatin a on viability and microRNA expression in human pancreatic cancer cell line BxPC-3
-
Zhang S, Cai X, Huang F, Zhong W, Yu Z. Effect of trichostatin a on viability and microRNA expression in human pancreatic cancer cell line BxPC-3. Exp Oncol 2008; 30: 265-268.
-
(2008)
Exp Oncol
, vol.30
, pp. 265-268
-
-
Zhang, S.1
Cai, X.2
Huang, F.3
Zhong, W.4
Yu, Z.5
-
16
-
-
68149126345
-
Chromatin remodeling at Alu repeats by epigenetic treatment activates silenced microRNA-512-5p with downregulation of Mcl-1 in human gastric cancer cells
-
Saito Y, Suzuki H, Tsugawa H, Nakagawa I, Matsuzaki J, Kanai Y, et al. Chromatin remodeling at Alu repeats by epigenetic treatment activates silenced microRNA-512-5p with downregulation of Mcl-1 in human gastric cancer cells. Oncogene 2009; 28: 2738-2744.
-
(2009)
Oncogene
, vol.28
, pp. 2738-2744
-
-
Saito, Y.1
Suzuki, H.2
Tsugawa, H.3
Nakagawa, I.4
Matsuzaki, J.5
Kanai, Y.6
-
17
-
-
32944462300
-
Rapid alteration of microRNA levels by histone deacetylase inhibition
-
Scott GK, Mattie MD, Berger CE, Benz SC, Benz CC. Rapid alteration of microRNA levels by histone deacetylase inhibition. Cancer Res 2006; 66: 1277-1281.
-
(2006)
Cancer Res
, vol.66
, pp. 1277-1281
-
-
Scott, G.K.1
Mattie, M.D.2
Berger, C.E.3
Benz, S.C.4
Benz, C.C.5
-
18
-
-
77956592888
-
microRNA-dependent modulation of histone acetylation in Waldenstrom macroglobulinemia
-
Roccaro AM, Sacco A, Jia X, Azab AK, Maiso P, Ngo HT, et al. microRNA-dependent modulation of histone acetylation in Waldenstrom macroglobulinemia. Blood 2010; 116: 1506-1514.
-
(2010)
Blood
, vol.116
, pp. 1506-1514
-
-
Roccaro, A.M.1
Sacco, A.2
Jia, X.3
Azab, A.K.4
Maiso, P.5
Ngo, H.T.6
-
19
-
-
64949190804
-
miR-449a targets HDAC-1 and induces growth arrest in prostate cancer
-
Noonan EJ, Place RF, Pookot D, Basak S, Whitson JM, Hirata H, et al. miR-449a targets HDAC-1 and induces growth arrest in prostate cancer. Oncogene 2009; 28: 1714-1724.
-
(2009)
Oncogene
, vol.28
, pp. 1714-1724
-
-
Noonan, E.J.1
Place, R.F.2
Pookot, D.3
Basak, S.4
Whitson, J.M.5
Hirata, H.6
-
20
-
-
31744432337
-
The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation
-
Chen JF, Mandel EM, Thomson JM, Wu Q, Callis TE, Hammond SM, et al. The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation. Nat Genet 2006; 38: 228-233.
-
(2006)
Nat Genet
, vol.38
, pp. 228-233
-
-
Chen, J.F.1
Mandel, E.M.2
Thomson, J.M.3
Wu, Q.4
Callis, T.E.5
Hammond, S.M.6
-
21
-
-
68949184660
-
Up-regulated microRNA-143 transcribed by nuclear factor kappa B enhances hepatocarcinoma metastasis by repressing fibronectin expression
-
Zhang X, Liu S, Hu T, He Y, Sun S. Up-regulated microRNA-143 transcribed by nuclear factor kappa B enhances hepatocarcinoma metastasis by repressing fibronectin expression. Hepatology 2009; 50: 490-499.
-
(2009)
Hepatology
, vol.50
, pp. 490-499
-
-
Zhang, X.1
Liu, S.2
Hu, T.3
He, Y.4
Sun, S.5
-
22
-
-
79960391940
-
miR-200a Regulates SIRT1 and epithelial to mesenchymal transition (EMT)-like transformation in mammary epithelial cells
-
Eades G, Yao Y, Yang M, Zhang Y, Chumsri S, Zhou Q. miR-200a Regulates SIRT1 and epithelial to mesenchymal transition (EMT)-like transformation in mammary epithelial cells. J Biol Chem 2011; 286: 25992-26002.
-
(2011)
J Biol Chem
, vol.286
, pp. 25992-26002
-
-
Eades, G.1
Yao, Y.2
Yang, M.3
Zhang, Y.4
Chumsri, S.5
Zhou, Q.6
-
23
-
-
79953329774
-
The Notch ligand Jagged2 promotes lung adenocarcinoma metastasis through a miR-200-dependent pathway in mice
-
Yang Y, Ahn YH, Gibbons DL, Zang Y, Lin W, Thilaganathan N, et al. The Notch ligand Jagged2 promotes lung adenocarcinoma metastasis through a miR-200-dependent pathway in mice. J Clin Invest 2011; 121: 1373-1385.
-
(2011)
J Clin Invest
, vol.121
, pp. 1373-1385
-
-
Yang, Y.1
Ahn, Y.H.2
Gibbons, D.L.3
Zang, Y.4
Lin, W.5
Thilaganathan, N.6
-
24
-
-
54049084380
-
A double-negative feedback loop between ZEB1-SIP1 and the microRNA-200 family regulates epithelial-mesenchymal transition
-
Bracken CP, Gregory PA, Kolesnikoff N, Bert AG, Wang J, Shannon MF, et al. A double-negative feedback loop between ZEB1-SIP1 and the microRNA-200 family regulates epithelial-mesenchymal transition. Cancer Res 2008; 68: 7846-7854.
-
(2008)
Cancer Res
, vol.68
, pp. 7846-7854
-
-
Bracken, C.P.1
Gregory, P.A.2
Kolesnikoff, N.3
Bert, A.G.4
Wang, J.5
Shannon, M.F.6
-
25
-
-
77953248068
-
HDAC4 inhibits the transcriptional activation of mda-7/IL-24 induced by Sp1
-
Pan L, Pan H, Jiang H, Du J, Wang X, Huang B, et al. HDAC4 inhibits the transcriptional activation of mda-7/IL-24 induced by Sp1. Cell Mol Immunol 2010; 7: 221-226.
-
(2010)
Cell Mol Immunol
, vol.7
, pp. 221-226
-
-
Pan, L.1
Pan, H.2
Jiang, H.3
Du, J.4
Wang, X.5
Huang, B.6
-
26
-
-
58249096131
-
HDAC4 represses p21(WAF1/Cip1) expression in human cancer cells through a Sp1-dependent, p53-independent mechanism
-
Mottet D, Pirotte S, Lamour V, Hagedorn M, Javerzat S, Bikfalvi A, et al. HDAC4 represses p21(WAF1/Cip1) expression in human cancer cells through a Sp1-dependent, p53-independent mechanism. Oncogene 2009; 28: 243-256.
-
(2009)
Oncogene
, vol.28
, pp. 243-256
-
-
Mottet, D.1
Pirotte, S.2
Lamour, V.3
Hagedorn, M.4
Javerzat, S.5
Bikfalvi, A.6
-
27
-
-
20944450160
-
Combinatorial microRNA target predictions
-
Krek A, Grün D, Poy MN, Wolf R, Rosenberg L, Epstein EJ, et al. Combinatorial microRNA target predictions. Nat Genet 2005; 37: 495-500.
-
(2005)
Nat Genet
, vol.37
, pp. 495-500
-
-
Krek, A.1
Grün, D.2
Poy, M.N.3
Wolf, R.4
Rosenberg, L.5
Epstein, E.J.6
-
28
-
-
43049103824
-
The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1
-
Gregory PA, Bert AG, Paterson EL, Barry SC, Tsykin A, Farshid G, et al. The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. Nat Cell Biol 2008; 10: 593-601.
-
(2008)
Nat Cell Biol
, vol.10
, pp. 593-601
-
-
Gregory, P.A.1
Bert, A.G.2
Paterson, E.L.3
Barry, S.C.4
Tsykin, A.5
Farshid, G.6
-
29
-
-
54349100901
-
HDAC4 promotes growth of colon cancer cells via repression of p21
-
Wilson AJ, Byun DS, Nasser S, Murray LB, Ayyanar K, Arango D, et al. HDAC4 promotes growth of colon cancer cells via repression of p21. Mol Biol Cell 2008; 19: 4062-4075.
-
(2008)
Mol Biol Cell
, vol.19
, pp. 4062-4075
-
-
Wilson, A.J.1
Byun, D.S.2
Nasser, S.3
Murray, L.B.4
Ayyanar, K.5
Arango, D.6
-
30
-
-
78449274443
-
Global histone acetylation levels: prognostic relevance in patients with renal cell carcinoma
-
Mosashvilli D, Kahl P, Mertens C, Holzapfel S, Rogenhofer S, Hauser S, et al. Global histone acetylation levels: prognostic relevance in patients with renal cell carcinoma. Cancer Sci 2010; 101: 2664-2669.
-
(2010)
Cancer Sci
, vol.101
, pp. 2664-2669
-
-
Mosashvilli, D.1
Kahl, P.2
Mertens, C.3
Holzapfel, S.4
Rogenhofer, S.5
Hauser, S.6
-
31
-
-
73949115353
-
Deficient histone acetylation and excessive deacetylase activity as epigenomic marks of prostate cancer cells
-
Cang S, Feng J, Konno S, Han L, Liu K, Sharma SC, et al. Deficient histone acetylation and excessive deacetylase activity as epigenomic marks of prostate cancer cells. Int J Oncol 2009; 35: 1417-1422.
-
(2009)
Int J Oncol
, vol.35
, pp. 1417-1422
-
-
Cang, S.1
Feng, J.2
Konno, S.3
Han, L.4
Liu, K.5
Sharma, S.C.6
-
32
-
-
34249774568
-
Transcriptional silencing of the TMS1/ASC tumour suppressor gene by an epigenetic mechanism in hepatocellular carcinoma cells
-
Zhang C, Li H, Zhou G, Zhang Q, Zhang T, Li J, et al. Transcriptional silencing of the TMS1/ASC tumour suppressor gene by an epigenetic mechanism in hepatocellular carcinoma cells. J Pathol 2007; 212: 134-142.
-
(2007)
J Pathol
, vol.212
, pp. 134-142
-
-
Zhang, C.1
Li, H.2
Zhou, G.3
Zhang, Q.4
Zhang, T.5
Li, J.6
-
33
-
-
79952110352
-
HDAC inhibitors and cancer therapy
-
Atadja PW. HDAC inhibitors and cancer therapy. Prog Drug Res 2011; 67: 175-195.
-
(2011)
Prog Drug Res
, vol.67
, pp. 175-195
-
-
Atadja, P.W.1
-
34
-
-
34250324192
-
Aminosuberoyl hydroxamic acids (ASHAs): a potent new class of HDAC inhibitors
-
Belvedere S, Witter DJ, Yan J, Secrist JP, Richon V, Miller TA. Aminosuberoyl hydroxamic acids (ASHAs): a potent new class of HDAC inhibitors. Bioorg Med Chem Lett 2007; 17: 3969-3971.
-
(2007)
Bioorg Med Chem Lett
, vol.17
, pp. 3969-3971
-
-
Belvedere, S.1
Witter, D.J.2
Yan, J.3
Secrist, J.P.4
Richon, V.5
Miller, T.A.6
-
35
-
-
57149138434
-
MicroRNA involvement in hepatocellular carcinoma
-
Gramantieri L, Fornari F, Callegari E, Sabbioni S, Lanza G, Croce CM, et al. MicroRNA involvement in hepatocellular carcinoma. J Cell Mol Med 2008; 12: 2189-2204.
-
(2008)
J Cell Mol Med
, vol.12
, pp. 2189-2204
-
-
Gramantieri, L.1
Fornari, F.2
Callegari, E.3
Sabbioni, S.4
Lanza, G.5
Croce, C.M.6
-
36
-
-
33646157967
-
Comprehensive analysis of microRNA expression patterns in hepatocellular carcinoma and non-tumorous tissues
-
Murakami Y, Yasuda T, Saigo K, Urashima T, Toyoda H, Okanoue T, et al. Comprehensive analysis of microRNA expression patterns in hepatocellular carcinoma and non-tumorous tissues. Oncogene 2006; 25: 2537-2545.
-
(2006)
Oncogene
, vol.25
, pp. 2537-2545
-
-
Murakami, Y.1
Yasuda, T.2
Saigo, K.3
Urashima, T.4
Toyoda, H.5
Okanoue, T.6
-
37
-
-
0036161439
-
Enzymatic activity associated with class II HDACs is dependent on a multiprotein complex containing HDAC3 and SMRT/N-CoR
-
Fischle W, Dequiedt F, Hendzel MJ, Guenther MG, Lazar MA, Voelter W, et al. Enzymatic activity associated with class II HDACs is dependent on a multiprotein complex containing HDAC3 and SMRT/N-CoR. Mol Cell 2002; 9: 45-57.
-
(2002)
Mol Cell
, vol.9
, pp. 45-57
-
-
Fischle, W.1
Dequiedt, F.2
Hendzel, M.J.3
Guenther, M.G.4
Lazar, M.A.5
Voelter, W.6
-
38
-
-
34249819336
-
MicroRNA-mediated feedback and feedforward loops are recurrent network motifs in mammals
-
Tsang J, Zhu J, van Oudenaarden A. MicroRNA-mediated feedback and feedforward loops are recurrent network motifs in mammals. Mol Cell 2007; 26: 753-767.
-
(2007)
Mol Cell
, vol.26
, pp. 753-767
-
-
Tsang, J.1
Zhu, J.2
van Oudenaarden, A.3
-
39
-
-
79956143950
-
p53 regulates epithelial-mesenchymal transition through microRNAs targeting ZEB1 and ZEB2
-
Kim T, Veronese A, Pichiorri F, Lee TJ, Jeon YJ, Volinia S, et al. p53 regulates epithelial-mesenchymal transition through microRNAs targeting ZEB1 and ZEB2. J Exp Med 2011; 208: 875-883.
-
(2011)
J Exp Med
, vol.208
, pp. 875-883
-
-
Kim, T.1
Veronese, A.2
Pichiorri, F.3
Lee, T.J.4
Jeon, Y.J.5
Volinia, S.6
-
40
-
-
77954234485
-
Down-regulated microRNA-152 induces aberrant DNA methylation in hepatitis B virus-related hepatocellular carcinoma by targeting DNA methyltransferase 1
-
Huang J, Wang Y, Guo Y, Sun S. Down-regulated microRNA-152 induces aberrant DNA methylation in hepatitis B virus-related hepatocellular carcinoma by targeting DNA methyltransferase 1. Hepatology 2010; 52: 60-70.
-
(2010)
Hepatology
, vol.52
, pp. 60-70
-
-
Huang, J.1
Wang, Y.2
Guo, Y.3
Sun, S.4
-
41
-
-
35649020283
-
MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B
-
Fabbri M, Garzon R, Cimmino A, Liu Z, Zanesi N, Callegari E, et al. MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B. Proc Natl Acad Sci U S A 2007; 104: 15805-15810.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 15805-15810
-
-
Fabbri, M.1
Garzon, R.2
Cimmino, A.3
Liu, Z.4
Zanesi, N.5
Callegari, E.6
|