The anti-erythrocyte autoimmune response of NZB mice. Identification of two distinct autoantigens

Immunology

Volumn 91, Issue 2, 1997, Pages 246-251

  Diiullo, N A ^a   Fairchild, R L ^a   Caulfield, M J ^a,b  

^a LERNER RESEARCH INSTITUTE   (United States)

^b MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIGEN; EPITOPE; GLYCOSIDASE; MONOCLONAL ANTIBODY; PROTEINASE K;

ANIMAL CELL; ANTIGEN DETECTION; ANTIGEN EXPRESSION; ANTIGEN RECOGNITION; ARTICLE; AUTOIMMUNE HEMOLYTIC ANEMIA; AUTOIMMUNITY; CONTROLLED STUDY; ERYTHROLEUKEMIA CELL; IMMUNOPATHOGENESIS; IMMUNOPRECIPITATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION;

EID: 8244262433     PISSN: 00192805     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2567.1997.00248.x     Document Type: Article

References (30)

1. LONG G., HOLMES MC. & BURNET F.M. (1963) Autoantibodies produced against mouse erythrocytes in NZB mice. Austr J Exp Biol Med Sci 41, 315.
2. CALKINS C.E. & CAULFIELD M.J. (1993) Experimental models of autoimmune hemolytic anemia. In: The Molecular Pathology of Autoimmunity (ed. C.A. Bona, K. Simonovitch, A.N. Theofilopoulos & M. Zanetti), p. 451. Harwood Academic Publishers, London.
3. LINDER E. & EDGINGTON T.S. (1972) Antigenic specificity of anti-erythrocyte auto-antibody responses by NZB mice: identification and partial characterization of two erythrocyte surface autoantigens. J Immunol 108, 1615.
4. BARKER R.N., OLIVEIRA G.G.D.S., ELSON C.J. & LYDYARD P.M. (1993) Pathogenic autoantibodies in the NZB mouse are specific for erythrocyte band 3 protein. Eur J Immunol 23, 1723.
5. SHAKLAI N.J.Y. & RANNY H.M. (1977) Classification and localization of hemoglobin binding sites on the red blood cell membrane. Biochemistry 16, 5593.
6. STRAPAZON E. & STECK T.L. (1976) Binding of rabbit muscle aldolase to band 3, the predominant polypeptide of the human erythrocyte membrane. Biochemistry 15, 1421.
7. KOPITO R. & LODISH H.F. (1985) Primary structure and transmembrane orientation of the murine anion exchange protein. Nature 316, 234.
8. BARKER R.N. & ELSON C.J. (1993) Red cell-reactive non-specific immunoglobulins and autoantibodies in the sera of normal and anaemic dogs. Vet Immunol Immunopathol 39, 339.
9. VICTORIA E.J., PIERCE S.W., BRANKS M.J. & MASOUREDIS S.P. (1990) IgG red blood cell autoantibodies in autoimmune hemolytic anemia bind to epitopes on red blood cell membrane band 3 glycoprotein. J Lab Clin Med 115, 74.
10. LEDDY J.P., FALANY J.L., KISSEL G.E., PASSADOR S.T. & ROSENFELD S.I. (1993) Erythrocyte membrane proteins reactive with human (warm-reacting) anti-red cell autoantibodies. J Clin Invest 91, 1672.
11. LUTZ H.U. (1992) Naturally occuring anti-band 3 antibodies. Trans Med Rev 6, 201.
12. KAY M.B. (1981) Isolation of the phagocytosis-inducing IgG-binding antigen on senescent somatic cells. Nature 289, 491.
13. KAY M.M.B. (1984) Localization of senescent cell antigen on band 3. Proc Natl Acad Sci USA 81, 5753.
14. CUNNINGHAM A.J. & STEELE E.J. (1981) Ontogeny of the autoimmune reaction in normal mice to antigens in erythrocytes and gut. Clin exp Immunol 44, 38.
15. HAYAKAWA K., HARDY R.R., PARKS D.R. & HERZENBERG L.A. (1983) The 'Ly-1B' cell subpopulation in normal, immuno-defective, and autoimmune mice. J Exp Med 157, 202.
16. DEHEER D.H. & EDGINGTON T.S. (1976) Cellular events associated with the immunogenesis of anti-erythrocyte autoantibody responses of NZB mice. Transplant Rev 31, 116.
17. CABRAL A.R., CABIEDES J. & ALARCON-SEGOVIA D. (1990) Hemolytic anemia related to an IgM autoantibody to phosphatidylcholine that binds in vitro to stored and to bromelain-treated human erythrocytes. J Autoimmunity 3, 773.
18. COSTEA N., YAKULIS V. & HELLER P. (1970) Cold reacting antibody in NZB/B1 mice. Blood 35, 583.
19. CAULFIELD M.J., STANKO D. & CALKINS C.E. (1989) Characterization of the spontaneous autoimmune (anti-erythrocyte) response in NZB mice using a pathogenic monoclonal autoantibody and its anti-idiotype. Immunology 66, 233.
20. CAULFIELD M.J. & STANKO D. (1992) A pathogenic monoclonal antibody, G8, is characteristic of anti-erythrocyte autoantibodies from Coombs-positive NZB mice. J Immunol 148, 2068.
21. FRIEND C., SHER W., HOLLAND J.G. & SATO T. (1971) Hemoglobin synthesis in murine virus-induced leukemic cells in vitro: stimulation of erythroid differentiation by dimethyl sulfoxide. Proc Natl Acad Sci USA 68, 378.
22. RUBIN H. (1963) Antibody elution from red blood cells. J Clin Pathol 16, 70.
23. WOJCHOWSKI D.M. & SYTKOWSKI A.J. (1986) Hybridoma production by simplified avidin-mediated electrofusion. J Immunol Methods 90, 173.
24. LAEMMLI U.K. (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227, 680.
25. BARDALES R.M. & BHAVANANDAN V.P. (1989) Transglycosylation and transfer reaction activities of endo-α-N-acetyl-d-galactosaminidase from Diplococcus (Streptococcus) pneumoniae. J Biol Chem, 264, 19 893.
26. RAIDA M.J., WENDEL E., KOJRO F. et al. (1989) Major proteolytic fragments of the murine band 3 protein as obtained after in situ proteolysis. Biochem Biophys Acta 980, 291.
27. SHIBATA T., BERNEY T., REININGER L. et al. (1990) Monoclonal anti-erythrocyte autoantibodies derived from NZB mice cause autoimmune hemolytic anemia by two distinct pathogenic mechanisms. Int Immunol 2, 1133.
28. OLIVEIRA G.G.D.S., IZUI S., RAVIRAJAN C.T. et al. (1996) Diverse antigen specificity of erythrocyte-reactive monoclonal autoantibodies from NZB mice. Clin Exp Immunol 105, 313.
29. MILLER R.D. & CALKINS C.E. (1988) Suppressor T cells and self-tolerance. Active suppression required for normal regulation of anti-erythrocytes autoantibody responses in spleen cells from nonautoimmune mice. J Immunol 140, 3779.
30. CALKINS C.E., COCHRAN S.A., MILLER R.D. & CAULFIELD M.J. (1990) Evidence for regulation of the autoimmune anti-erythrocyte response by idiotype-specific suppressor T cells in NZB mice. Int Immunol 2, 127.