High frequency of antibiotic resistance among Gram-negative isolates in intensive care units at 10 Swedish hospitals

Clinical Microbiology and Infection

Volumn 3, Issue 2, 1997, Pages 208-215

  Hanberger, Håkan ^a   Nilsson, Lennart E ^a   Brorson, J E ^b   Claesson, B ^b   Fritz, H ^b   Ripa, T ^b   Jorbeck H ^b   Karnell A ^b   Larsson, P ^b   Lovestad A ^b   Malmborg, A S ^b   Rydberg, J ^b   Rylander, M ^b  

^a LINKÖPING UNIVERSITY HOSPITAL   (Sweden)

^b NONE

Author keywords

Gram negative bacteria; Intensive care units; Nosocomial infections; Resistance

Indexed keywords

ANTIBIOTIC AGENT; CEFOTAXIME; CEFTAZIDIME; CEFTRIAXONE; CEFUROXIME; CIPROFLOXACIN; COTRIMOXAZOLE; GENTAMICIN; IMIPENEM; PIPERACILLIN; PIPERACILLIN PLUS TAZOBACTAM; TOBRAMYCIN;

ACINETOBACTER; ANTIBIOTIC RESISTANCE; ARTICLE; CITROBACTER; CONTROLLED STUDY; ENTEROBACTER; ESCHERICHIA COLI; GRAM NEGATIVE BACTERIUM; HAEMOPHILUS; HOSPITAL INFECTION; INTENSIVE CARE; KLEBSIELLA; MINIMUM INHIBITORY CONCENTRATION; MORGANELLA MORGANII; NONHUMAN; PRIORITY JOURNAL; PROTEUS; PSEUDOMONAS; PSEUDOMONAS AERUGINOSA; SERRATIA; STENOTROPHOMONAS MALTOPHILIA; SWEDEN;

EID: 8244251429     PISSN: 1198743X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1469-0691.1997.tb00599.x     Document Type: Article

References (29)

1. Vincent JL, Bihari DJ, Sucer PM, et al. The prevalence of nosocomial infection in intensive care units in Europe: results of the European prevalence of infection in intensive care (EPIC) study. J Am Med Assoc 1995; 274: 639-44.
2. Trilla A. Epidemiology of nosocomial infections in adult intensive care units. Intensive Care Med 1994; 20(suppl): S1-4.
3. Widmer AF. Infection control and prevention strategies in the ICU. Intensive Care Med 1994; 20S. 7-11.
4. Farr BM. Infection control in intensive care units: modern problems, modern solutions. Curr Opin Infect Dis 1993; 6: 520-5.
5. Jumaa P, Chattopadhayay B. Outbreak of gentamicin, ciprofloxacin-resistant Pseudomonas aeruginosa in an intensive care unit, traced to contaminated quivers. J Hosp Infect 1994; 28: 209-18.
6. Lingnau W, Allerberger F. Control of an outbreak of methicillin-resistant Staphylococcus aureas (MRSA) by hygienic measures in a general intensive care unit. Infection 1994; 22 (suppl 2): S135-9.
7. Fish DN, Piscitelli SC, Danziger LH. Development of resistance during antimicrobial therapy: a review of antibiotic classes and patient characteristics in 173 studies. Pharmacotherapy 1995; 15: 279-91.
8. Casell GH, Archer G, Beam TR, et al. Reports of the ASM task force on antibiotic resistance. Antimicrob Agents Chemother Suppl. 1995: S1-23.
9. Cunha BA. Intensive care not intensive antibiotics Heart Lung 1994; 23: 361-2.
10. Kollef MH. Antibiotic use and antibiotic resistance in the intensive care unit: are we curing or creating disease? Heart Lung 1994; 23: 363-7.
11. Dornbusch K, Bengtsson S, Brorsson JE, et al. Susceptibility to betalactam antibiotics and gentamicin of Gram-negative bacilli isolated from hospitalized patients: a Swedish multicenter study. Scand J Infect Dis 1988; 20: 641-7
12. Dornbusch K, The European Study Group on Antibiotic Resistance. Resistance to β-lactam antibiotics and ciprofloxacin in Gram-negative bacilli and staphylococci isolated from blood: a European collaborative study. J Antimicrob Chemother 1990; 26: 269-78.
13. Dornbusch K, King A, Phillips I, Legakis NJ. Antibiotic resistance levels in European blood and urine isolates. A collaborative study [abstract 259]. In. Abstracts of the 7th European Congress of Clinical Microbiology and Infectious Diseases, Vienna, Austria. European Society of Clinical Microbiology and Infectious Diseases, 1995: 50.
14. Olsson-Liljequist B, Burman LG. Susceptibility of Swedish blood isolates to piperacilin-tazobactam compared with other antibiotics in 1992. In Einhorn J, Nord CE, Norrby R, eds. Recent advances in chemotherapy and bacterial infections. Washington, DC: American Society for Microbiology, 1994: 191.2.
15. Walder M, Karlsson E, Nilsson B. Sensitivity of 880 blood culture isolates to 24 antibiotics. Scand J Infect Dis 1994; 26: 67-75.
16. Hanberger H, Nilsson LE. Antibiotics: increased resistance among enterococci and enterobacteriacae. Lakartidningen 1996; 93: 148-54.
17. Baquero F, Cantón R, Martinez-Beltrán J, Bolmström A. The E-test as an epidemiological tool. Diagn Microbiol Infect Dis 1992; 15: 483-7.
18. Brown DFJ, Brown L. Evaluation of the E test, a novel method of quantifying antimicrobial activity. J Antimicrob Chemother 1991; 27: 185-90.
19. Sanchez ML, Jones RN. E Test, an antimicrobial susceptibility testing method with broad clinical and epidemiological application. Antimicrobic Newsletter 1993; 8: 1-8.
20. Olsson-Liljequist B, Larsson P, Walder M, Miörner H. Methodology for susceptibility testing. Scand J Infect Dis 1997; in press.
21. National Committee for Clinical Laboratory Standards (NCCLS). Performance standards for antimicrobial susceptibility testing (M100-S6; Table 2). NCCLS, 1995; 15: No 14, Villanova Pa.
22. Cormican MG, Marshall SA, Jones RN. Detection of extended-spectrum β-lactemase (ESβL)-producing strains by the Etest ESBL Screen. J Clin Microbiol 1996; 34: 1880-4.
23. Sanders CC. Cefepime: the next generation? Clin Infect Dis 1993; 17: 369-79.
24. Sirot D. Extended spectrum plasmid-mediated betalactamases. J Antimicrob Chemother 1995; 36(suppl A): S19-34.
25. Fung-Tomc JC, Gradelski E, Huczko E, et al. Differences in the resistant variants of Enterobacter cloacae selected by extended-spectrum cephalosporins. Antimicrob Agents Chemother 1996; 40: 1289-93.
26. Livermore DM. β-lactamases in laboratory and clinical resistance. Clin Microbiol Rev 1995, 8: 557-84.
27. Chow J, Fine M, Shlaes D, et al. Enterobacter bacteremia: clinical features and emergence of antibiotic resistance during therapy Ann Intern Med 1991; 115: 585-90.
28. Gould IM. Risk factors for acquisition of multiple drug-resistant Gram-negative bacteria. Eur J Clin Microbiol Infect Dis 1994; 13(suppl 1): S30-8.
29. Spenser RC. The emergence of epidemic, multiple-antibiotic-resistant Stenotrophomonas (Xanthomonas) maltophilia and Burkholderia (Pseudomonas) cepacia. J Hosp Infect 1995; 30(suppl). S453-64.