Increased efficacy of aphidicolin killing of human neuroblastoma cells in vitro by encapsulation in liposomes

Neoplasma

Volumn 44, Issue 2, 1997, Pages 91-95

  Cinatl Jr , J ^a   Hernaiz Driever P ^a   Cinatl, J ^a   Ruckert D G ^b   Gumbel H O ^a   Rabenau, H ^a   Kornhuber, B ^a   Doerr, H W ^a  

^a GOETHE UNIVERSITY   (Germany)

^b UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

Aphidicolin; cell killing; liposomes; neuroblastoma

Indexed keywords

APHIDICOLIN; CHOLESTEROL; LIPOSOME; PHOSPHATIDYLCHOLINE; PHOSPHATIDYLSERINE;

ARTICLE; CELL KILLING; CELL SURVIVAL; CONTROLLED STUDY; ENCAPSULATION; HUMAN; HUMAN CELL; NEUROBLASTOMA CELL;

EID: 8244247119     PISSN: 00282685     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. BARLETT, G.R.: Phosphorus assay in column chromatography. J. Biol. Chem., 234, 1959, 466-473.
2. CINATL, J., GUSSETIS, E.S., CINATL, J. Jr., EBENER, U., MAINKE, M., SCHWABE, D., DOERR, H.W., KORNHUBER, B.: Differentiation arrest in neuroblastoma cell culture. J. Cancer Res. Clin. Oncol., Suppl., 116, 1990, 915.
3. CINATL, J. Jr., CINATL, J., MAINKE, M., WEISSFLOG, A., STEIGMANN, G., RABENAU, H., DOERR, H.W., KORNHUBER, B.: Aphidicolin selectively kills neuroblastoma cells in vitro. Cancer Lett., 67, 1992, 199-206.
4. DAMIA, G., TAGLIABUE, G., ZUCCHETTI, M., DAVOLI, E., SESSA, C., CAVALLI, F., D'INCALCI, M.: Activity of aphidicolin alone or in combination with cisplatin in a murine ovarian tumor resistant to cisplatin. Cancer Chemother. Pharmacol., 30, 1992, 459-464.
5. FAN, D., BUCANA, C.D., O'BRIAN, C.A., ZWELLING, K.A., SEID, C., FIDLER, I.J.: Enhancement of murine tumor cell sensitivity to adriamycin by presentation of the drug in phosphatidylcholine-phosphatidylserine liposomes. Cancer Res., 50, 1990, 3619-3626.
6. GRIFFIN, J., MUNROE, D., MAJOR, P., KUFE, D.: Induction of differentiation of human myeloid leukemia cells by inhibitors of DNA synthesis. Exp. Hematol., 10. 1982, 774-781.
7. HOPE, M.J., MAYER, L.D., CULLIS, P.R.: Vesicles of variable sizes produced by a rapid extrusion procedure. Biochem. Biophys. Acta, 858, 1986, 161-168.
8. IKEGAMI, S., TAGUCHI, T., OMASHI, M., OGURRO, M., NAGANO, H., MANO, Y.: Aphidicolin prevents mitotic cell division by interfering with the activity of DNA polymerase α. Nature (London), 275, 1978, 458-460.
9. LILIAKIS, G., NUSSE, M., BRYANT, P.: Effects of aphidicolin on cell proliferation, repair of potentially lethal damage and repair of DNA strand breaks in Ehrlich ascites tumor cells exposed to X-rays. Int. J. Radiat. Biol., 42, 1982, 417-434.
10. MASUDA, H., OZOLS, R.F., LAI, G., FOJO, A., ROTHENBERG, M., HAMILTON, T.C.: Increased DNA repair as a mechanism of acquired resistance to cis-diaminodichlorplatinum (II) in human ovarian cancer cell lines. Cancer Res., 48, 1988, 5713-5716.
11. MASUDA, M., TANAKA, T., MATSUDA, H., KUSABA, L: Increased removal of DNA-bound platinum in a human ovarium cancer cell line resistant to cis-diaminodichlorplatinum (II). Cancer Res., 50, 1990, 1863-1866.
12. MURATE, T., HOTTA, T., TSUSHITA, K., SUZUKI, M., YOSHIDA, T., SAGA, S., SAITO, H., YOSHIDA, S.A.: Aphidicolin, an inhibitor of DNA replication, blocks theTPA-induced differentiation of a human megakaryoblastic cell line, MEG-01. Blood, 78, 1991, 3168-3177.
13. MURATE, T., KAGAMI, Y, HOTTA, T., YOSHIDA, T., SAITO, H., YOSHIDA, S.: Terminal differentiation of human erythroleukemia Cell line K562 induced by aphidicolin. Exp. Cell Res., 191, 1990, 45-50.
14. ROTONDO, S., ZUCCHETTI, M., SESSA, C., D'INCALCI, M., BENFENATI, E., FANELLI, R.: A gas Chromatographic mass spectrometric assay for the determination of aphidicolin in plasma of cancer patients. J. Pharmacol. Sci., 78, 1989, 399-411.
15. SADASIVAN, R., MORGAN, R., FANIAN, C., STEPHENS, R.: Reversal of multi-drug resistance in HL-60 cells by verapamil and liposome-encapsulated doxorubicin. Cancer Lett., 57, 1991, 165-171.
16. 4-oleyl-cytosine arabinoside. In: Liposomes in the Therapy of Infectious Diseases and Cancer. Eds: Lopez-Berenstein, G., Fidler, I.J. New York, Alan R. Liss Inc. 1989, 95-110.
17. SESSA, C., ZUCCHETTI, M., DAVOLI, E., CALIFANO, R., CAVALLI, F., FRUSTACI, S., GUMBRELL, L., SULKES, A., WINOGRAD, B., D'INCALCI, M.: Phase I clinical pharmacological evaluation of aphidicolin glycinate, INCI, 83, 1991, 1160-1164.
18. SZOKA, C. Jr.: The future of liposomal drug delivery. Biotechnol. Appl. Biochem. J. Natl. Cancer. Inst, 12, 1990, 496-500.
19. TANG, S., POULIN, L., LEVY, J.A.: Lack of human immunodeficiency virus type 1 (HIV-1) replication and accumulation of viral DNA in HIV-1-infected T cells blocked in replication. J. Gen. Virol., 73, 1992, 933-939.
20. TREAT, J., GREENSPAN, A.R., RAHMAN, A.: Liposome encapsulated doxorubicin: Preliminary results of phase I and phase II trials. In: Liposomes in Therapy of Infectious Diseases and Cancer. Eds: Lopez-Berenstein, G., Fidler, I.J. New York, Alan R. Liss Inc. 1989, 353-357.
21. TUMULOWICZ, J.J., NICHOLS, W.W., CHOLON, J.J., GREEN, A.J.: Definition of a continuous human cell line derived from neuroblastoma. Cancer Res., 30, 1970, 2110-2118.
22. WARREN, L., JARDILLER, J.C., MALARSKA, A., AKELI, M.G.: Increased accumulation of drugs in multidrug-resistant cells induced by liposomes. Cancer Res., 52, 1992, 3241-3245.