The location of acidic fibroblast growth factor in the breast is dependent on the activity of proteases present in breast cancer tissue

British Journal of Cancer

Volumn 75, Issue 11, 1997, Pages 1621-1630

  Coope, R C ^a   Browne, P J ^a   Yiangou, C ^a   Bansal, G S ^a   Walters, J ^b   Groome, N ^b   Shousha, S ^a   Johnston, C L ^a   Coombes, R C ^a   Gomm, J J ^a  

^a IMPERIAL COLLEGE SCHOOL OF MEDICINE   (United Kingdom)

^b OXFORD BROOKES UNIVERSITY   (United Kingdom)

Author keywords

Breast cancer; Fibroblast growth factor 1; Immunohistochemistry; Protease

Indexed keywords

ACIDIC FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR RECEPTOR; FIBROBLAST GROWTH FACTOR RECEPTOR 1; FIBROBLAST GROWTH FACTOR RECEPTOR 4; MESSENGER RNA; PROTEINASE; PROTEINASE INHIBITOR; RECEPTOR SUBTYPE; UNCLASSIFIED DRUG;

ARTICLE; AUTOCRINE EFFECT; BASEMENT MEMBRANE; BENIGN TUMOR; BREAST BIOPSY; BREAST CANCER; CANCER CELL; CARCINOMA CELL; CELL TYPE; CONTROLLED STUDY; ENZYME ACTIVITY; EPITHELIUM CELL; FEMALE; FIBROCYSTIC BREAST DISEASE; FIBROSARCOMA; FROZEN SECTION; HUMAN; HUMAN TISSUE; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; INVASIVE CARCINOMA; LACTATION; MAJOR CLINICAL STUDY; MUCINOUS CARCINOMA; MYOEPITHELIUM CELL; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEINASE INHIBITION; STROMA;

EID: 8244231276     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/bjc.1997.277     Document Type: Article

References (58)

1. Adnane J, Gaudray P, Dionne CA, Crumley G, Jaye M, Schlessinger J, Jeanteur P, Birnbaum D and Theillet C (1991) BEK and FLG. two receptor members of the FGF family, are amplified in subsets of human breast cancers. Oncogene, 6: 659-663
2. Akutsu Y, Aida T, Nakazawa S and Asano G (1991) Localisation of acidic and basic fibroblast growth factor mRNA in human brain tumours. Jpn J Cancer Res 82: 1022-1027
3. Anandappa SY, Winstanley JHR, Leinster S, Green B, Rudland PS and Barraclough R (1994) Comparative expression of fibroblast growth factor mRNAs in benign and malignant breast disease. Br J Cancer 69: 772-776
4. Atherton E and Sheppard RC (1985) Solid phase peptide synthesis using N-fluorenylmethoxycarbonyl amino acid penta-fluorophenyl esters. J Chem Soc Chem Commun 165-166
5. Bansal GS, Johnston CL, Coope RC, Gomm JJ, Luqmani YA, Coombes RC and Yiangou C (1995) Expression of fibroblast growth factor I is lower in breast cancer than in normal human breast. Br J Cancer 72: 1420-1426
6. Basilico C and Moscatelli D (1992) The FGF family of growth factors and oncogenes. Adv Cancer Res 5: 115-164
7. Basset P, Bellocq JP, Wolf C, Stoll I, Hutin P, Limacher JM, Podhajcer OL, Chenard MP, Rio MC and Chambon P (1991) A novel metalloproteinase gene specifically expressed in stromal cells of breast carcinomas. Nature 348: 699-704
8. Briozzo P, Badet J, Capony F, Pieri I, Montcourrier P, Barritault D and Rochefort H (1991) MCF7 mammary cancer cells respond to bFGF and internalize it following its release from extracellular matrix: a permissive role of cathepsin D. Exp Cell Res 194: 252-259
9. Cam Y, Neumann M-R, Oliver L, Raulais D, Janet T and Ruch J-V (1992) Immunolocalization of acidic and basic fibroblast growth factors during mouse odontogenesis. Int J Dev Biol 36: 381-389
10. Cao Y and Pettersson R (1993) Release and subcellular localization of acidic fibroblast growth factor expressed to high levels in HeLa cells. Growth Factors 8: 277-291
11. Caruelle D, Groux-Muscatelli B, Gaudric A, Sestier C, Coscas G, Caruelle J-P and Barritault D (1989) Immunological study of acidic fibroblast growth factor (aFGF) distribution in the eye. J Cell Biochem 39: 117-128
12. Chen W-T, Lee C-C, Goldstein L, Bernier S, Liu CHL, Lin C-Y, Yeh Y, Monsky WL, Kelly T, Dai M, Zhou J-Y and Mueller SC (1994) Membrane proteases as potential diagnostic and therapeutic targets for breast malignancy. Breast Cane Res Treat 31: 217-226.
13. Chopin DK, Caruelle J-P, Colombel M, Palcy S, Ravery V, Caruelle D, Abbou C and Barritault D (1993) Increased immunodetection of acidic fibroblast growth factor in bladder cancer, detectable in urine. J Urology 150: 1126-1130
14. Church GM and Gilbert W (1984) Genomic sequencing. Proc Natl Acad Sci USA 81: 1991-1995
15. Clarke MSF, Khakee, R and McNeil PL (1993) Loss of cytoplasmic basic fibroblast growth factor from physiologically wounded myofibers of normal and dystrophic muscle. J Cell Science 106: 121-133
16. Coleman-Krnacik S and Rosen JM (1994) Differential temporal and spatial gene expression of fibroblast growth factor family members during mouse mammary gland development. Mol Endocrinol 8: 218-229
17. Dickson RB, Shi YE and Johnson MD (1994) Matrix-degrading proteases in hormone-dependent breast cancer. Breast Cancer Res Treat 31: 167-173
18. Engelmann GL, Dionne CA and Jaye MC (1993) Acidic fibroblast growth factor and heart development. Role in myocyte proliferation and capillary angiogenesis. Circ Res 72: 7-19
19. Fallon JH, Di Salvo J, Loughlin SE, Gimenez-Gallego G, Seroogy KB, Bradshaw RA, Morrison RS, Ciofi P and Thomas KA (1992) Localization of acidic fibroblast growth factor within the mouse brain using biochemical and immunocytochemical techniques. Growth Factors 6: 139-157
20. Faucheux BA, Cohen SY, Delaere P, Tourbah A, Dupuis C, Hartmann MP, Jeanny JC, Hauw JJ and Courtois Y (1992) Glial cell localization of acidic fibroblast growth factor-like immunoreactivity in the optic nerve of young adult and aged mammals. Gerontology 38: 308-314
21. Feinberg AP and Vogelstein BA (1983) A technique for radiolabelling DNA restriction endonuclease fragments to high specific activity. Anal Biochem 132: 6-13
22. Fu Y-M, Spirito P, Yu Z-X, Biro S, Sasse J, Lei J, Ferrans VJ, Epstein SE and Casscells W (1991) Acidic fibroblast growth factor in the developing rat embryo. J Cell Biol 114: 1261-1273
23. Galfre G and Milstein C (1981) Preparation of monoclonal antibodies: strategies and procedures. Methods Enzymol 73: 3-36
24. Givol D and Yayon A (1992) Complexity of FGF receptors: genetic basis for structural diversity and functional specificity. FASEB J 6: 3362-3369
25. Gomm JJ, Smith J, Ryall GK, Baillie R, Turnbull L and Coombes RC (1991) Localisation of basic fibroblast growth factor and transforming growth factor β1 in the human mammary gland. Cancer Res 51: 4685-4692
26. Gomm JJ, Browne PB, Coope RC, Liu QY, Buluwela L and Coombes RC (1995) Isolation of pure populations of epithelial and myoepithelial cells from the normal human mammary gland using immunomagnetic separation with Dynabeads. Anal Biochem 226: 91-99
27. Gordon PB, Choi HU, Conn G, Ahmed A, Ehrmann B, Rosenberg L and Hatcher VB (1989) Extracellular matrix heparan sulfate proteoglycans modulate the mitogenic capacity of acidic fibroblast growth factor. J Cell Physiol 140: 584-592
28. Hanneken A and Baird A (1992) Immunolocalization of basic fibroblast growth factor: dependence on antibody type and tissue fixation (letter). Exp Eye Res 54: 1011-1014
29. Healy AM and Herman IM (1992) Density-dependent accumulation of FGF2 in subendothelial matrix. Eur J Cell Biol 59: 56-67
30. Hughes S and Hall P (1993) Immunolocalization of fibroblast growth factor receptor 1 and its ligands in human tissues. Lab Invest 69: 173-182
31. Ishigooka H, Aotaki-Keen AE and Hjelmeland LM. Subcellular localization of bFGF in human retinal pigment epithelium in vitro. Exp Eye Res 55: 203-214
32. Jaakkola S, Salmikangas P, Nylund S, Partanen J, Armstrong E, Pyrhonen S, Lehtovirta P and Nevanlinna H (1993) Amplification of fgfr4 gene in human breast and gynecological cancers. Int J Cancer 54: 378-382
33. Jacquemier J, Adelaide J, Parc P, Penault-Llorca F, Planche J, Delapeyriere O and Birnbaum D (1994) Expression of the FGFR1 gene in human breast-carcinoma cells. Int J Cancer 59: 373-378
34. Jaye M, Schlessinger J and Dionne CA (1992) Fibroblast growth factor receptor tyrosine kinases: molecular analysis and signal transduction. Biochim Biophys Acta 1135: 185-199
35. Johnston CL, Cox HC, Gomm JJ and Coombes RC (1995) bFGF and aFGF induce membrane ruffling in breast cancer cells but not in normal breast epithelial cells: FGFR-4 involvement. Biochem J 306: 609-616
36. Kandel J, Bossy-Wetzel E, Radvanyi F, Klagsbrun M, Folkman, J and Hanahan D (1991) Neovascularisation is associated with a switch to export of bFGF in the multistep development of fibrosarcoma. Cell 66: 1095-1104
37. Kataoka H, Decastro R, Zucker S and Biswas C (1993) Tumor cell-derived collagenase-stimulatory factor increases expression of interstitial collagenase, stromelysin, and 72-kda gelatinase. Cancer Res 53: 3154-3158
38. Klagsbrun M and Baird A (1991) A dual receptor system is required for basic fibroblast growth factor activity. Cell 67: 229-231
39. Klagsbrun M (1990) The affinity of fibroblast growth factors (FGFs) for heparin: FGF-heparin sulfate interactions in cells and extracellular matrix. Curr Opin Cell Biol 2: 857-863
40. Koshinaga M, Sanon HR and Whittemore SR (1993) Altered acidic and basic fibroblast growth factor expression following spinal cord injury. Exp Neurol 120: 32-18
41. Li F, Strange R, Friis RR, Djonov V, Altermatt H-J, Saurer S, Niemann H and Andres A-C (1994) Expression of stromelysin-1 and TIMP-1 in the involuting mammary gland and in early invasive tumors of the mouse. Int J Cancer 59: 560-568
42. Luqmani YA, Graham M and Coombes RC (1992a) Expression of basic fibroblast growth factor, FGFR1 and FGFR2 in normal and malignant human breast, and comparison with other normal tissues. Br J Cancer 66: 273-280
43. Luqmani YA, Smith J and Coombes RC (1992b) Polymerase chain reaction-aided analysis of gene expression in frozen tissue sections. Anal Biochem 200: 291-295
44. Luqmani YA, Mortimer C, Yiangou C, Johnston CL, Bansal GS, Sinnett D, Law M and Coombes RC (1995) Expression of two variant forms of fibroblast growth factor receptor I in human breast. Int J Cancer 64: 274-279
45. Mignatti P, Morimoto T and Rifkin DB (1992) Basic fibroblast growth factor released by single, isolated cells stimulates their migration in an autocrine manner. Proc Natl Acad Sci USA 88: 11007-11011
46. Miyamoto M Naruo KH, Seko C, Matsumoto S, Kondo T and Kurokawa T (1993) Molecular cloning of a novel cytokine cDNA encoding the ninth member of the fibroblast growth factor family, which has a unique secretion property. Mol Cell Biol 13: 4251-4259
47. Morrison CA, Fishleigh RV, Ward DJ and Robson B (1987) Computer aided design and physiological testing of a luteinising hormone-releasing hormone analogue for 'adjuvant free' immunocastration. FEBS Lett 214: 65-70
48. Partanen J, Vainikka S, Korhonen J, Armstrong E and Alitalo K (1992) Diverse receptors for fibroblast growth factors. Prog Growth Factor Res 4: 69-83
49. Penault-Llorca F, Bertucci F, Adelaide J, Pare P, Coulier F, Jacquemier J, Birnbaum D and Delapeyriere O (1995) Expression of FGF and FGF receptor genes in human breast cancer. Int J Cancer 61: 170-176
50. Smith J, Yelland A, Baille R and Coombes RC (1994) Acidic and basic fibroblast growth factors in human breast. Eur J Cancer 30A: 496-503
51. Stock A, Kuzis K, Woodward WR, Nishi R and Eckenstein FP (1992) Localization of acidic fibroblast growth factor in specific subcortical neuronal populations. J Neuroscience 12: 4688-4700
52. Tanaka AK, Miyamoto N, Minamiro M, Takeda M, Sato M, Matsuo H and Matsumoto K (1992) Cloning and characterization of an androgen-induced growth factor essential for the androgen-dependent growth of mouse mammary carcinoma cells. Proc Natl Acad Sci USA 89: 8928-8932
53. Thomas KA, Rios-Candelore M and Fitzpatrick S (1984) Purification and characterisation of acidic fibroblast growth factor from bovine brain. Proc Natl Acad Sci USA 81: 357-361
54. Vainikka S, Partanen J, Bellosta P, Coulier F, Basilico C, Jaye M and Alitalo K (1992) Fibroblast growth factor receptor-4 shows novel features in genomic structure, ligand binding and signal transduction. EMBO J 11: 4273-4280
55. Weiner HL and Swain JL (1989) Acidic fibroblast growth factor mRNA is expressed by cardiac myocytes in culture and the protein is localised to the extracellular matrix. Proc Natl Acad Sci USA 86: 2683-2687
56. Wolf C, Rouyer N, Lutz Y, Adida C, Loriot M, Bellocq J-P, Chambon P and Bassett P (1993) Stromelysin 3 belongs to a subgroup of proteinases expressed in breast carcinoma fibroblastic cells and possibly implicated in tumor progression. Proc Natl Acad Sci USA 90: 1843-1847
57. Yamanaka Y, Friess H, Buchler M, Beger HG, Uchida E, Onda M, Kobrin MS and Korc M (1993) Overexpression of acidic and basic fibroblast growth factors in human pancreatic cancer correlates with advanced tumour stage. Cancer Res 53: 5289-5296
58. Yeoman LC (1993) An autocrine model for cell- and matrix-associated fibroblast growth factor. Oncol Res 5: 489-499