Epstein-barr viral BNLF2a protein hijacks the tail-anchored protein insertion machinery to block antigen processing by the transport complex TAP

Journal of Biological Chemistry

Volumn 286, Issue 48, 2011, Pages 41402-41412

  Wycisk, Agnes I ^a   Lin, Jiacheng ^a   Loch, Sandra ^a   Hobohm, Kathleen ^a   Funke, Jessica ^a   Wieneke, Ralph ^a   Koch, Joachim ^a,c   Skach, William R ^b   Mayerhofer, Peter U ^a   Tampé, Robert ^a  

^a GOETHE UNIVERSITY   (Germany)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^c INSTITUTE FOR TUMOR BIOLOGY AND EXPERIMENTAL THERAPY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN PROCESSING; ATP-BINDING CASSETTE TRANSPORTERS; CELL SURFACES; CYTOTOXIC T LYMPHOCYTES; ENDOPLASMIC RETICULUM MEMBRANES; IMMUNE SURVEILLANCE; INHIBITION MECHANISMS; MAJOR HISTOCOMPATIBILITY COMPLEX CLASS; PEPTIDE LOADING; TAIL-ANCHORED PROTEINS; VIRUS-INFECTED CELLS;

CELL MEMBRANES; MACHINERY; MAMMALS; PROTEINS; VIRUSES;

ANTIGENS;

ABC TRANSPORTER; CARRIER PROTEIN; MEMBRANE PROTEIN; PROTEIN ASNA 1; PROTEIN BNLF2A; TRANSPORTER ASSOCIATED WITH ANTIGEN PROCESSING; TRYPTOPHAN RICH BASIC PROTEIN; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ANIMAL CELL; ANTIGEN PRESENTATION; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; EPSTEIN BARR VIRUS; HUMAN; HUMAN CELL; MOLECULAR MECHANICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN FUNCTION; PROTEIN PROCESSING;

ANIMALS; ANTIGEN PRESENTATION; ARSENITE TRANSPORTING ATPASES; ATP-BINDING CASSETTE TRANSPORTERS; ENDOPLASMIC RETICULUM; EPSTEIN-BARR VIRUS INFECTIONS; HELA CELLS; HERPESVIRUS 4, HUMAN; HISTOCOMPATIBILITY ANTIGENS CLASS I; HUMANS; MULTIPROTEIN COMPLEXES; NUCLEAR PROTEINS; SPODOPTERA; VIRAL MATRIX PROTEINS;

EID: 82355184481     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.237784     Document Type: Article

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