β1-adrenergic receptors increase UCP1 in human MADS brown adipocytes and rescue cold-acclimated β3-adrenergic receptor knockout mice via nonshivering thermogenesis

American Journal of Physiology - Endocrinology and Metabolism

Volumn 301, Issue 6, 2011, Pages

  Mattsson, Charlotte L ^a   Csikasz, Robert I ^a   Chernogubova, Ekaterina ^a   Yamamoto, Daniel L ^a   Hogberg, Helena T ^a   Amri, Ez Zoubir ^b   Hutchinson, Dana S ^a,c   Bengtsson, Tore ^a  

^a STOCKHOLM UNIVERSITY   (Sweden)

^b UNIVERSITÉ CÔTE D'AZUR   (France)

^c MONASH UNIVERSITY   (Australia)

Author keywords

Brown adipose tissue; Human multipotent adipose derived stem cells; Obesity; Type 2 diabetes; Uncoupling protein 1

Indexed keywords

BETA 1 ADRENERGIC RECEPTOR; BETA 3 ADRENERGIC RECEPTOR; CYCLIC AMP; MESSENGER RNA; UNCOUPLING PROTEIN 1; ION CHANNEL; MITOCHONDRIAL PROTEIN; MITOCHONDRIAL UNCOUPLING PROTEIN;

ADIPOSE DERIVED STEM CELL; ANIMAL EXPERIMENT; ARTICLE; BROWN ADIPOSE TISSUE; CELL DIFFERENTIATION; CELL FUNCTION; COLD EXPOSURE; CONTROLLED STUDY; GENE SILENCING; HUMAN; HUMAN CELL; MALE; METABOLIC PARAMETERS; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; NONSHIVERING THERMOGENESIS; OBESITY; PRIORITY JOURNAL; PROTEIN FUNCTION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; THERMOREGULATION; ACCLIMATIZATION; ANIMAL; CELL CULTURE; COLD; CYTOLOGY; DOWN REGULATION; FEMALE; GENETIC EPISTASIS; GENETICS; METABOLISM; MOUSE MUTANT; MULTIPOTENT STEM CELL; PHYSIOLOGY; SHIVERING; THERMOGENESIS;

ACCLIMATIZATION; ADIPOCYTES, BROWN; ANIMALS; CELL DIFFERENTIATION; CELLS, CULTURED; COLD TEMPERATURE; DOWN-REGULATION; EPISTASIS, GENETIC; FEMALE; HUMANS; ION CHANNELS; MALE; MICE; MICE, KNOCKOUT; MITOCHONDRIAL PROTEINS; MULTIPOTENT STEM CELLS; RECEPTORS, ADRENERGIC, BETA-1; RECEPTORS, ADRENERGIC, BETA-3; SHIVERING; THERMOGENESIS;

EID: 82355183970     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00085.2011     Document Type: Article

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