Down-regulated HS6ST2 in osteoarthritis and kashin-beck disease inhibits cell viability and influences expression of the genes relevant to aggrecan metabolism of human chondrocytes

Rheumatology

Volumn 50, Issue 12, 2011, Pages 2176-2186

  Wang, Wei ^a   Zhong, Bo ^a   Sun, Jian ^a   Cao, Junling ^a   Tian, Juan ^a   Zhong, Nannan ^a   Zhao, Wenxiang ^a   Tian, Lifang ^a   Xu, Peng ^a   Guo, Dawei ^a   Ju, Xichi ^a   Ma, Wei ^a   Li, Meng ^a   Hou, Weikun ^a   Lu, Shemin ^a  

^a MEDICAL SCHOOL OF XI AN JIAOTONG UNIVERSITY   (China)

Author keywords

Heparan sulphate 6 o sulphotransferase 2; Kashin beck disease; Osteoarthritis; Suppression subtractive hybridization

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; AGGRECAN; AGGRECANASE 1; AGGRECANASE 2; DISINTEGRIN; HEPARAN SULPHATE 6 O SULPHOTRANSFERASE 2; MESSENGER RNA; METALLOPROTEINASE; PROTEOHEPARAN SULFATE; SMALL INTERFERING RNA; STROMELYSIN; TOLONIUM CHLORIDE; TRANSCRIPTION FACTOR SOX9; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CARTILAGE CELL; CELL LINE; CELL VIABILITY; CLINICAL ARTICLE; CONTROLLED STUDY; DOWN REGULATION; FEMALE; GENE; GENE EXPRESSION; GENE IDENTIFICATION; GENETIC SCREENING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; KASHIN BECK DISEASE; MALE; NUCLEOTIDE SEQUENCE; OSTEOARTHRITIS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN METABOLISM; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SUPPRESSION SUBTRACTIVE HYBRIDIZATION;

ADAM PROTEINS; ADULT; AGED; AGGRECANS; ANALYSIS OF VARIANCE; CARTILAGE, ARTICULAR; CELL LINE; CELL SURVIVAL; CHONDROCYTES; DNA, COMPLEMENTARY; DOWN-REGULATION; FEMALE; GENE EXPRESSION; HUMANS; KASHIN-BECK DISEASE; MALE; MATRIX METALLOPROTEINASE 3; MIDDLE AGED; OSTEOARTHRITIS; PHENOTYPE; RNA, MESSENGER; RNA, SMALL INTERFERING; SOX9 TRANSCRIPTION FACTOR; SULFOTRANSFERASES; TRANSFECTION;

EID: 82355172672     PISSN: 14620324     EISSN: 14620332     Source Type: Journal    
DOI: 10.1093/rheumatology/ker230     Document Type: Article

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