Mutational analysis of xenobiotic metabolizing genes (CYP1A1 and GSTP1) in sporadic head and neck cancer patients

Genetics and Molecular Biology

Volumn 34, Issue 4, 2011, Pages 533-538

  Masood, Nosheen ^a   Kayani, Mahmood Akhtar ^a  

^a COMSATS Institute of Information and Technology ^*  (Pakistan)

Author keywords

CYP1A1; GSTP1; Head and neck cancer; Mutations; Polymorphisms

Indexed keywords

ADULT; AMINO ACID SUBSTITUTION; ARTICLE; CANCER RISK; CONTROLLED STUDY; CYP1A1 GENE; FEMALE; FRAMESHIFT MUTATION; GENE DELETION; GENE INSERTION; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GSTP1 GENE; HEAD AND NECK CANCER; HUMAN; MAJOR CLINICAL STUDY; MALE; MUTATIONAL ANALYSIS; MUTATOR GENE; NUCLEOTIDE SEQUENCE; PAKISTAN; SEQUENCE ANALYSIS;

EID: 82355164479     PISSN: 14154757     EISSN: 16784685     Source Type: Journal    
DOI: 10.1590/S1415-47572011005000034     Document Type: Article

References (32)

1. Ali OF, Akande O, Antoun G, Mao FX and Boulamwini J (1997) Molecular cloning, characterization, and expression in Escherichia coli, of full length cDNA of three human glu-tathione S-transferase P1 gene variants. Evidence for differential catalytic activity of the encoded proteins. J Biol Chem 272:10004-10012.
2. Bartsch H, Nair U, Risch A, Rojas M, Wikman H and Alexandrov K (2000) Genetic polymorphism of CYP genes, alone or in combination, as a risk modifier of tobacco-related cancers. Cancer Epidemiol Biomarker Prevent 9:3-28.
3. Baumgartner-Parzer S, Schulze E, Waldhäusl W, Pauschenwein S, Rondot S, Nowotny P, Meyer K, Frisch H, Waldhauser F and Vierhapper H (2001) Mutational spectrum of the steroid21-hydroxylase gene in Austria: Identification of a novel missense mutation.J Clin Endocrinol Metab 86:4771-4775.
4. Cascorbi I, Brockmoller J and Roots I (1996) A C4887A polymorphism in exon 7 of human CYP1A1: Population frequency, mutation linkages, and impact on lung cancer susceptibility. Cancer Res 56:4965-4969.
5. Chevalier D, Allorge D, Lo-Guidice JM, Cauffiez C, Lhermitte M, Lafitte JJ and Broly F (2001) Detection of known and two novel (M331I and R464S) missense mutations inthe human CYP1A1 gene in a French Caucasian population. Hum Mutat 17:355.
6. Cho CG, Lee SK and Nam SY (2006) Association of GSTP1 and NQO1 polymorphism and head and neck squamous cell carcinoma risk. J Korean Med Sci 21:1075-1079.
7. Cocco R, Stenberg G, Dragani B, Rossi D, Paludi D, Mannervik B and Aceto A (2001) The folding and stability of human alpha class glutathione transferase A1-1 depend on distinct roles of a conserved N-capping box and hydrophobic staple motif. J Biol Chem 276:32177-183.
8. Crofts F, Cosma GN, Currie D, Taioli E, Toniolo P and Garte SJ (1993) A novel CYP1A1 gene polymorphism in African-Americans. Carcinogenesis 14:1729-1731.
9. Curran JE, Weinstein SR and Griffiths LR (2000) Polymorphisms of glutathione S transferase genes (GSTM1, GSTP1 and GSTT1) and breast cancer susceptibility. Cancer Lett 153:113-120.
10. Devasena A, Pranay MC, Sadhana K, Rajani AB and Manoj BM (2007) Susceptibility to oral cancer by genetic polymorphisms at CYP1A1, GSTM1 and GSTT1 loci among Indians: Tobacco exposure as a risk modulator. Carcinogenesis 28:1455-1462.
11. Dragani B, Stenberg G, Melino S, Petruzzelli R, Mannervik B and Aceto A (1997) The conserved N-capping box in the hydro-phobic core of glutathione S-transferase P1-1 is essential for refolding. Identification of a buried and conserved hydrogen bond important for protein stability. J Biol Chem 272:25518-25523.
12. Duk WP, Bohan J, Dongdeuk J, Kihwa Y, Jung DP, Yong SL and Doung R (2004) Genetic polymorphisms of CYP1A1 in a Korean population. Arch Toxicol 78:306-08.
13. Faheem A (2007) Cancer registration in Pakistan: Contemporary state of affairs. Asia Pac J Cancer Prevent 8:452-456.
14. Garte S, Gaspari L, Alexandrie AK, Ambrosone C and Autrup H (2001) Metabolic gene polymorphism frequencies in control populations. Cancer Epidemiol Biomarker Prevent 10:1239-1248.
15. Hanif M, Zaidi P, Kamal S and Hameed A (2009) Institution-based cancer incidence in a local population in Pakistan: Nine year data analysis. Asia Pac J Cancer Prevent 10:227-230.
16. Hayashi S, Watanabe J, Nakachi K, and Kawajiri K (1991) Genetic linkageof lung cancer-associated MspI polymorphisms with amino acid replacement in the heme binding region of the human cytochrome P450IA1 gene. J Biochem (Tokyo) 110:407-411.
17. Lewin F, Norell S, Johansson H, Gustavsson P, Wennerberg J, Biorklund A and Rutqvist L (1998) Smoking tobacco, oral snuff, and alcohol in the etiology of squamous cell carcinoma of the head and neck: A population-based case-referent study in Sweden. Cancer 82:1367-1375.
18. Moyer AM, Salvaggione OE, Wu T-Y, Moon I, Eckloff BW, Hildebrandt MAT, Schaid DJ, Wieben ED and Weinshil-boum RM (2008) Glutathione S transferase P1: Gene sequence variation and functional genomic studies. Cancer Res 68:4791-4801.
19. Parkin DM, Pisani P and Ferlay J (1993) Estimates of the worldwide incidence of eighteen major cancers in 1985. Intl J Cancer 54:594-606.
20. Peters EH, McClean MD, Marsit CJ, Luckett B and Kelsey KT (2006) Glutathione S transferase polymorphism and the synergy of alcohol and tobacco in oral, pharyngeal and laryn-geal carcinoma. Cancer Epidemiol Biomarkers Prevent 15:2196-2202.
21. Rajani B, Aparna K and Shama B (2003) Polymorphism at CYP and GST gene loci and susceptibility to tobacco related cancers. Proc Ind Natl Sci Acad 69:35-48.
22. Rossjohn J, McKinstry WJ, Oakley AJ, Parker MW, Stenberg G, Mannervik B, Dragani B, Cocco R and Aceto A (2000) Structures of thermolabile mutants of human glutathione transferase P1. J Mol Biol 302:295-302.
23. Saito S, Iida A, Sekine A, Ogawa C, Kawauchi S, Higuchi S, Ohno M and Nakamura Y (2002) 906 variations among 27 genes encoding cytochrome P450 (CYP) enzymes and aldehyde dehydrogenases (ALDHs) in the Japanese population. J Hum Genet 47:419-444.
24. Sheen P, Méndez M, Gilman RH, Peña L, Caviedes L, Zimic MJ, Zhang Y, Moore DAJ and Evans CA (2009) Sputum pcr-single-strand conformational polymorphism test for same-day detection of pyrazinamide resistance in tuberculosis patients. Clin Microbiol 47:2937-2943.
25. Smart J and Daly AK (2000) Variation in induced CYP1A1 levels: Relationship to CYP1A1, Ah receptor and GSTM1 polymorphisms. Pharmacogenetics 10:11-24.
26. Spurr NK, Gough AC, Stevenson K and Wolf CR (1987) Msp-1 polymorphism detected with a cDNA probe for the P-450 I family on chromosome 15. Nucleic Acids Res 15:5901.
27. Stenberg G, Dragani B, Cocco R, Mannervik B and Aceto A (2000) Conserved "hydrophobic staple motif" plays a crucial role in the refolding of human glutathione transferase P1. J Biol Chem 275:10421-10428.
28. Telenti A, Imboden P, Marchesi F, Schmidheini F and Bodmer T (1993) Direct, automated detection of rifampin-resistant mycobacterium tuberculosis by polymerase chain reaction and single-strand conformation polymorphism analysis, Antimicrob Agents Chemotherap 37:2054-2058.
29. Toru H, Masaharu Y, Shinji T and Kazuaki C (2008) Genetic polymorphisms and head and neck cancer risk. Int J Oncol 32:945-973.
30. Vierhapper H, Bieglmayer C, Heinze G and Baumgartner-Parzer SM (2004) Frequency of RET protooncogene mutations in patients with normal and with moderately elevated (50-100 pg/mL) penta gastrin-stimulated serum concentrations of calcitonin. Thyroid 14:580-583.
31. Xiang DL, Brett C and Oliver H (2001) Loss of CYP1A1 messenger RNA expression due to nonsense-mediated decay. Mol Pharmacol 60:388-393.
32. Zimniak P, Nanduri B, Pikula S, Bandorowicz PJ, Singhal SS and Srivastava SK (1994) Naturally occurring glutathione S-transferase GSTP1 isoforms with isoleucine and valine in position 104 differ in enzymic properties. Eur J Biochem 224:893-899.