Cytological and histological detection of amyloid deposits in bone marrow of patients affected by multiple myeloma

Leukemia and Lymphoma

Volumn 52, Issue 12, 2011, Pages 2304-2307

  Petruzziello, Fara ^a   Zeppa, Pio ^a   Ciancia, Giuseppe ^a   Cozzolino, Immacolata ^a   Fernandez, Laura Sosa ^a   Cervasio, Mariarosaria ^a   Musto, Pellegrino ^b   D'Auria, Fiorella ^b   Vita, Giulia ^b   Morabito, Fortunato ^c   Piro, Eugenio ^d   Ponti, Maria Rita Costanza ^d   Pettinato, Guido ^a   Ciancia, Rosanna ^a   Pane, Fabrizio ^a   Catalano, Lucio ^a  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^b IRCCS   (Italy)

^c Annunziata Hospital   (Italy)

^d PUGLIESE CIACCIO HOSPITAL   (Italy)

Author keywords

Congo red; Immunoglobulin light chain amyloidosis; Multiple myeloma

Indexed keywords

AMYLOID; CONGO RED; IMMUNOGLOBULIN A; IMMUNOGLOBULIN KAPPA CHAIN; IMMUNOGLOBULIN LAMBDA CHAIN; IMMUNOGLOBULIN M;

ADULT; AGED; AMYLOIDOSIS; ARTICLE; BONE MARROW; BONE MARROW BIOPSY; CLINICAL ARTICLE; CLINICAL EVALUATION; CONTROLLED STUDY; CYTOLOGY; DISEASE SEVERITY; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; ILIAC BONE; INTERMETHOD COMPARISON; MALE; MULTIPLE MYELOMA; PRIORITY JOURNAL;

ADULT; AGED; AGED, 80 AND OVER; BIOPSY, NEEDLE; BONE MARROW; FEMALE; HUMANS; MALE; MIDDLE AGED; MULTIPLE MYELOMA; PLAQUE, AMYLOID; RETROSPECTIVE STUDIES;

EID: 82255196149     PISSN: 10428194     EISSN: 10292403     Source Type: Journal    
DOI: 10.3109/10428194.2011.594192     Document Type: Article

References (8)

1. Desikan KR, Dhodapkar MV, Hough A, et al. Incidence and impact of light chain associated (AL) amyloidosis on the prognosis of patients with multiple myeloma treated with autologous transplantation. Leuk Lymphoma 1997;27:315-319. (Pubitemid 27501190)
2. Vela-Ojeda J, Garcia-Ruiz Esparza MA, Padilla-Gonzalez Y, et al. Multiple myeloma-associated amyloidosis is an indepen dent high-risk prognostic factor. Ann Hematol 2009;88:59-66.
3. Petruzziello F, Zeppa P, Catalano L, et al. Amyloid in bone marrow smears of patients af ected by multiple myeloma. Ann Hematol 2010;89:469-474.
4. Siragusa S, Morice W, Gertz MA, et al. Asymptomatic immunoglobulin light chain amyloidosis (AL) at the time of diagnostic bone marrow biopsy in newly diagnosed patients with multiple myeloma and smouldering multiple myeloma. Ann Hematol 2011;90:101-106.
5. Cohen AS. Amyloidosis. In: Williams WJ, Beutler E, Erslev AJ, Lichtman MA, editors. Hematology. New York: McGraw-Hill; 1995. pp 1137-1146.
6. Müller MS, Geibel A, Neumann HPH, et al. Primary (AL) amyloidosis in plasma cell disorders. Oncologist 2006;11:824-830. (Pubitemid 44157570)
7. Perfetti V, Casarini S, Palladini G, et al. Analysis of V(lambda)-J(lambda) expression in plasma cells from primary (AL) amyloidosis and normal bone marrow identif es 3r (lambdaIII) as a new amyloid-associated germline gene segment. Blood 2002;100:948-953. (Pubitemid 34832622)
8. Gertz MA. Immunoglobulin light chain amyloidosis: 2011 update on diagnosis, risk stratif cation, and management. Am J Hematol 2011;86:180-186.