The crystal structure of the TetR family transcriptional repressor SimR bound to DNA and the role of a flexible N-terminal extension in minor groove binding

Nucleic Acids Research

Volumn 39, Issue 21, 2011, Pages 9433-9447

  Le, Tung B K ^a,b   Schumacher, Maria A ^b,c   Lawson, David M ^a   Brennan, Richard G ^b,c   Buttner, Mark J ^a  

^a JOHN INNES CENTRE   (United Kingdom)

^b UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^c DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIMER; GYRASE INHIBITOR; PROTEIN SUBUNIT; PROTEINASE; SIMOCYCLINONE; SIMR PROTEIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; BACTERIAL GENE; BIOINFORMATICS; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; DNA BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN MOTIF; SIMR GENE; STREPTOMYCES ANTIBIOTICUS;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; BACTERIAL PROTEINS; COUMARINS; CRYSTALLOGRAPHY, X-RAY; DNA FOOTPRINTING; DNA, BACTERIAL; GLYCOSIDES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NUCLEIC ACID CONFORMATION; OPERATOR REGIONS, GENETIC; PROTEIN BINDING; REPRESSOR PROTEINS; SEQUENCE ALIGNMENT; SEQUENCE DELETION; STREPTOMYCES ANTIBIOTICUS;

EID: 82255194409     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkr640     Document Type: Article

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