메뉴 건너뛰기




Volumn 39, Issue 21, 2011, Pages

Daedalus: A robust, turnkey platform for rapid production of decigram quantities of active recombinant proteins in human cell lines using novel lentiviral vectors

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; CYTOKINE; IMMUNE RECEPTOR; LENTIVIRUS VECTOR; RECEPTOR; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG;

EID: 82255185569     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkr706     Document Type: Article
Times cited : (72)

References (59)
  • 1
    • 0032007853 scopus 로고    scopus 로고
    • Strategies for optimizing heterologous protein expression in Escherichia coli
    • DOI 10.1016/S0167-7799(97)01155-4, PII S0167779997011554
    • Hannig, G. and Makrides, S.C. (1998) Strategies for optimizing heterologous protein expression in Escherichia coli. Trends Biotechnol., 16, 54-60. (Pubitemid 28055472)
    • (1998) Trends in Biotechnology , vol.16 , Issue.2 , pp. 54-60
    • Hannig, G.1    Makrides, S.C.2
  • 2
    • 8344256552 scopus 로고    scopus 로고
    • Recombinant protein folding and misfolding in Escherichia coli
    • Baneyx, F. and Mujacic, M. (2004) Recombinant protein folding and misfolding in Escherichia coli. Nat. Biotechnol., 22, 1399-408.
    • (2004) Nat. Biotechnol. , vol.22 , pp. 1399-408
    • Baneyx, F.1    Mujacic, M.2
  • 4
    • 14744285206 scopus 로고    scopus 로고
    • Expression of heterologous proteins in Pichia pastoris: A useful experimental tool in protein engineenring and production
    • DOI 10.1002/jmr.687
    • Daly, R. and Hearn, M.T.W. (2005) Expression of heterologous proteins in Pichia pastoris: a useful experimental tool in protein engineering and production. J. Mol. Recogn., 18, 119-138, 10.1002/jmr.687. (Pubitemid 40328574)
    • (2005) Journal of Molecular Recognition , vol.18 , Issue.2 , pp. 119-138
    • Daly, R.1    Hearn, M.T.W.2
  • 5
    • 22844450442 scopus 로고    scopus 로고
    • Baculovirus as versatile vectors for protein expression in insect and mammalian cells
    • DOI 10.1038/nbt1095
    • Kost, T.A., Condreay, J.P. and Jarvis, D.L. (2005) Baculovirus as versatile vectors for protein expression in insect and mammalian cells. Nat. Biotechnol., 23, 567-575. (Pubitemid 41724895)
    • (2005) Nature Biotechnology , vol.23 , Issue.5 , pp. 567-575
    • Kost, T.A.1    Condreay, J.P.2    Jarvis, D.L.3
  • 6
    • 12244295475 scopus 로고    scopus 로고
    • Improvement of glycosylation in insect cells with mammalian glycosyltransferases
    • DOI 10.1016/S0168-1656(02)00364-4
    • Chang, G. (2003) Improvement of glycosylation in insect cells with mammalian glycosyltransferases. J. Biotechnol., 102, 61-71, 10.1016/S0168- 1656(02)00364-4. (Pubitemid 36369204)
    • (2003) Journal of Biotechnology , vol.102 , Issue.1 , pp. 61-71
    • Chang, G.-D.1    Chen, C.-J.2    Lin, C.-Y.3    Chen, H.-C.4    Chen, H.5
  • 7
    • 0035313635 scopus 로고    scopus 로고
    • Industrial choices for protein production by large-scale cell culture
    • DOI 10.1016/S0958-1669(00)00197-X
    • Chu, L. and Robinson, D.K. (2001) Industrial choices for protein production by large-scale cell culture. Curr. Opin. Biotechnol., 12, 180-187. (Pubitemid 32247406)
    • (2001) Current Opinion in Biotechnology , vol.12 , Issue.2 , pp. 180-187
    • Chu, L.1    Robinson, D.K.2
  • 9
    • 78751502820 scopus 로고    scopus 로고
    • Generation of stable, high-producing CHO cell lines by lentiviral vector-mediated gene transfer in serum-free suspension culture
    • 101002/bit.22968
    • Oberbek, A., Matasci, M., Hacker, D.L. and Wurm, F.M. (2010) Generation of stable, high-producing CHO cell lines by lentiviral vector-mediated gene transfer in serum-free suspension culture. Biotechnol. Bioeng., 41, 101002/bit.22968.
    • (2010) Biotechnol. Bioeng. , pp. 41
    • Oberbek, A.1    Matasci, M.2    Hacker, D.L.3    Wurm, F.M.4
  • 10
    • 77953069759 scopus 로고    scopus 로고
    • High-level recombinant protein production in CHO cells using lentiviral vectors and the cumate gene-switch
    • 10.1002/bit.22698
    • Gaillet, B., Gilbert, R., Broussau, S., Pilotte, A., Malenfant, F., Mullick, A., Garnier, A. and Massie, B. (2010) High-level recombinant protein production in CHO cells using lentiviral vectors and the cumate gene-switch. Biotechnol. Bioeng., 106, 203-215, 10.1002/bit.22698.
    • (2010) Biotechnol. Bioeng. , vol.106 , pp. 203-215
    • Gaillet, B.1    Gilbert, R.2    Broussau, S.3    Pilotte, A.4    Malenfant, F.5    Mullick, A.6    Garnier, A.7    Massie, B.8
  • 11
    • 2642553379 scopus 로고    scopus 로고
    • Sea urchin insulator protects lentiviral vector from silencing by maintaining active chromatin structure
    • DOI 10.1038/sj.gt.3302227
    • Hino, S., Fan, J., Taguwa, S., Akasaka, K. and Matsuoka, M. (2004) Sea urchin insulator protects lentiviral vector from silencing by maintaining active chromatin structure. Gene Ther., 11, 819-828, 10.1038/sj.gt.3302227. (Pubitemid 38714585)
    • (2004) Gene Therapy , vol.11 , Issue.10 , pp. 819-828
    • Hino, S.1    Fan, J.2    Taguwa, S.3    Akasaka, K.4    Matsuoka, M.5
  • 12
    • 28844494121 scopus 로고    scopus 로고
    • Epigenetic regulation of lentiviral transgene vectors in a large animal model
    • DOI 10.1016/j.ymthe.2005.07.685, PII S1525001605014097
    • Hofmann, A., Kessler, B., Ewerling, S., Kabermann, A., Brem, G., Wolf, E. and Pfeifer, A. (2006) Epigenetic regulation of lentiviral transgene vectors in a large animal model. Mol. Ther. J. Am. Soc. Gene Ther., 13, 59-66, 10.1016/j.ymthe.2005.07.685. (Pubitemid 41763483)
    • (2006) Molecular Therapy , vol.13 , Issue.1 , pp. 59-66
    • Hofmann, A.1    Kessler, B.2    Ewerling, S.3    Kabermann, A.4    Brem, G.5    Wolf, E.6    Pfeifer, A.7
  • 13
    • 12444283327 scopus 로고    scopus 로고
    • Transgenes encompassing dual-promoter CpG islands from the human TBP and HNRPA2B1 loci are resistant to heterochromatin-mediated silencing
    • DOI 10.1016/S0888-7543(03)00107-1
    • Antoniou, M., Harland, L., Mustoe, T., Williams, S., Holdstock, J., Yague, E., Mulcahy, T., Griffiths, M., Edwards, S., Ioannou, P. et al. (2003) Transgenes encompassing dual-promoter CpG islands from the human TBP and HNRPA2B1 loci are resistant to heterochromatin-mediated silencing. Genomics, 82, 269-279, 10.1016/S0888-7543(03)00107-1. (Pubitemid 36952300)
    • (2003) Genomics , vol.82 , Issue.3 , pp. 269-279
    • Antoniou, M.1    Harland, L.2    Mustoe, T.3    Williams, S.4    Holdstock, J.5    Yague, E.6    Mulcahy, T.7    Griffiths, M.8    Edwards, S.9    Ioannou, P.A.10    Mountain, A.11    Crombie, R.12
  • 14
    • 26944481086 scopus 로고    scopus 로고
    • CpG-island fragments from the HNRPA2B1/CBX3 genomic locus reduce silencing and enhance transgene expression from the hCMV promoter/enhancer in mammalian cells
    • 1710.1186/1472-675′-5-17
    • Williams, S., Mustoe, T., Mulcahy, T., Griffiths, M., Simpson, D., Antoniou, M., Irvine, A., Mountain, A. and Crombie, R. (2005) CpG-island fragments from the HNRPA2B1/CBX3 genomic locus reduce silencing and enhance transgene expression from the hCMV promoter/enhancer in mammalian cells. BMC Biotechnol., 5, 1710.1186/1472-675′-5-17.
    • (2005) BMC Biotechnol. , pp. 5
    • Williams, S.1    Mustoe, T.2    Mulcahy, T.3    Griffiths, M.4    Simpson, D.5    Antoniou, M.6    Irvine, A.7    Mountain, A.8    Crombie, R.9
  • 15
    • 34548843603 scopus 로고    scopus 로고
    • Lentiviral vectors containing an enhancer-less ubiquitously acting chromatin opening element (UCOE) provide highly reproducible and stable transgene expression in hematopoietic cells
    • DOI 10.1182/blood-2006-12-060814
    • Zhang, F., Thornhill, S.I., Howe, S.J., Ulaganathan, M., Schambach, A., Sinclair, J., Kinnon, C., Gaspar, H.B., Antoniou, M. and Thrasher, A.J. (2007) Lentiviral vectors containing an enhancer-less ubiquitously acting chromatin opening element (UCOE) provide highly reproducible and stable transgene expression in hematopoietic cells. Blood, 110, 1448-1457, 10.1182/blood-2006-12- 060814. (Pubitemid 47443959)
    • (2007) Blood , vol.110 , Issue.5 , pp. 1448-1457
    • Zhang, F.1    Thornhill, S.I.2    Howe, S.J.3    Ulaganathan, M.4    Schambach, A.5    Sinclair, J.6    Kinnon, C.7    Gaspar, H.B.8    Antoniou, M.9    Thrasher, A.J.10
  • 16
    • 77956265818 scopus 로고    scopus 로고
    • A ubiquitous chromatin opening element (UCOE) confers resistance to DNA methylation-mediated silencing of lentiviral vectors
    • 10.1038/mt.2010.132
    • Zhang, F., Frost, A., Blundell, M. and Bales, O. (2010) A ubiquitous chromatin opening element (UCOE) confers resistance to DNA methylation-mediated silencing of lentiviral vectors. Mol. Ther., 18, 1640-1649, 10.1038/mt.2010.132.
    • (2010) Mol. Ther. , vol.18 , pp. 1640-1649
    • Zhang, F.1    Frost, A.2    Blundell, M.3    Bales, O.4
  • 17
    • 33645103149 scopus 로고    scopus 로고
    • Woodchuck hepatitis virus post-transcriptional regulatory element deleted from X protein and promoter sequences enhances retroviral vector titer and expression
    • 10.1038/sj.gt.3302698
    • Schambach, A., Bohne, J., Baum, C., Hermann, F.G., Egerer, L., von Laer, D. and Giroglou, T. (2006) Woodchuck hepatitis virus post-transcriptional regulatory element deleted from X protein and promoter sequences enhances retroviral vector titer and expression. Gene Ther., 13, 641-645, 10.1038/sj.gt.3302698.
    • (2006) Gene Ther. , vol.13 , pp. 641-645
    • Schambach, A.1    Bohne, J.2    Baum, C.3    Hermann, F.G.4    Egerer, L.5    Von Laer, D.6    Giroglou, T.7
  • 18
    • 34249298695 scopus 로고    scopus 로고
    • Improving transcriptional termination of self-inactivating gamma-retroviral and lentiviral vectors
    • DOI 10.1038/sj.mt.6300152, PII 6300152
    • Schambach, A., Galla, M., Maetzig, T., Loew, R. and Baum, C. (2007) Improving transcriptional termination of self-inactivating gamma-retroviral and lentiviral vectors. Mol. Ther. J. Am. Soc. Gene Ther., 15, 1167-1173, 10.1038/sj.mt.6300152. (Pubitemid 46813620)
    • (2007) Molecular Therapy , vol.15 , Issue.6 , pp. 1167-1173
    • Schambach, A.1    Galla, M.2    Maetzig, T.3    Loew, R.4    Baum, C.5
  • 19
    • 34250766201 scopus 로고    scopus 로고
    • The Strep-tag system for one-step purification and high-affinity detection or capturing of proteins
    • DOI 10.1038/nprot.2007.209, PII NPROT.2007.209
    • Schmidt, T.G.M. and Skerra, A. (2007) The Strep-tag system for one-step purification and high-affinity detection or capturing of proteins. Nat. Protoc., 2, 1528-1535, 10.1038/nprot.2007.209. (Pubitemid 46952331)
    • (2007) Nature Protocols , vol.2 , Issue.6 , pp. 1528-1535
    • Schmidt, T.G.M.1    Skerra, A.2
  • 20
    • 77950397760 scopus 로고    scopus 로고
    • B cell-specific lentiviral gene therapy leads to sustained B-cell functional recovery in a murine model of X-linked agammaglobulinemia
    • 10.1182/blood-2009-09-241869
    • Kerns, H.M., Ryu, B.Y., Stirling, B.V., Sather, B.D., Astrakhan, A., Humblet-Baron, S., Liggitt, D. and Rawlings, D.J. (2010) B cell-specific lentiviral gene therapy leads to sustained B-cell functional recovery in a murine model of X-linked agammaglobulinemia. Blood, 115, 2146-2155, 10.1182/blood-2009-09-241869.
    • (2010) Blood , vol.115 , pp. 2146-2155
    • Kerns, H.M.1    Ryu, B.Y.2    Stirling, B.V.3    Sather, B.D.4    Astrakhan, A.5    Humblet-Baron, S.6    Liggitt, D.7    Rawlings, D.J.8
  • 22
    • 0033213239 scopus 로고    scopus 로고
    • The finer things in X-ray diffraction data collection
    • DOI 10.1107/S090744499900935X
    • Pflugrath, J.W. (1999) The finer things in X-ray diffraction data collection. Acta Crystallogr. Sect. D Biol. Crystallogr., 55, 1718-1725, 10.1107/S090744499900935X. (Pubitemid 29504426)
    • (1999) Acta Crystallographica Section D: Biological Crystallography , vol.55 , Issue.10 , pp. 1718-1725
    • Pflugrath, J.W.1
  • 25
    • 13244281317 scopus 로고    scopus 로고
    • Coot: Model-building tools for molecular graphics
    • DOI 10.1107/S0907444904019158
    • Emsley, P. and Cowtan, K. (2004) Coot: model-building tools for molecular graphics. Acta Crystallogr. D Biol. Crystallogr., 60, 2126-2132, S0907444904019158 [pii] 10.1107/S0907444904019158. (Pubitemid 41742764)
    • (2004) Acta Crystallographica Section D: Biological Crystallography , vol.60 , Issue.12 , pp. 2126-2132
    • Emsley, P.1    Cowtan, K.2
  • 26
    • 0030924992 scopus 로고    scopus 로고
    • Refinement of macromolecular structures by the maximum-likelihood method
    • DOI 10.1107/S0907444996012255
    • Murshudov, G.N., Vagin, A.A. and Dodson, E.J. (1997) Refinement of macromolecular structures by the maximum-likelihood method. Acta Crystallogr. D Biol. Crystallogr., 53, 240-255, 10.1107/S0907444996012255 S0907444996012255 [pii]. (Pubitemid 27235885)
    • (1997) Acta Crystallographica Section D: Biological Crystallography , vol.53 , Issue.3 , pp. 240-255
    • Murshudov, G.N.1    Vagin, A.A.2    Dodson, E.J.3
  • 27
    • 33646260450 scopus 로고    scopus 로고
    • Optimal Description of A Protein Structure in Terms of Multiple Groups Undergoing TLS Motion
    • 10.1107/S0907444906005270
    • Painter, J. and Merritt, E.A. (2006) Optimal description of a protein structure in terms of multiple groups undergoing TLS motion. Acta Crystallogr. Sect. D Biol. Crystallogr., 62, 439-45 10.1107/S0907444906005270.
    • (2006) Acta Crystallogr. Sect. D Biol. Crystallogr. , vol.62 , pp. 439-445
    • Painter, J.1    Merritt, E.A.2
  • 28
    • 33645158291 scopus 로고    scopus 로고
    • TLSMD web server for the generation of multi-group TLS models
    • 10.1107/S0021889805′38987
    • Painter, J. and Merritt, E.A. (2006) TLSMD web server for the generation of multi-group TLS models. J. Appl. Crystallogr., 39, 109-111, 10.1107/S0021889805′38987.
    • (2006) J. Appl. Crystallogr. , vol.39 , pp. 109-111
    • Painter, J.1    Merritt, E.A.2
  • 31
    • 33646185923 scopus 로고    scopus 로고
    • Roles of glycodelin in modulating sperm function
    • S0303-7207(05)00484-3 [pii] 10.1016/j.mce.2005.,12.038
    • Yeung, W.S., Lee, K.F., Koistinen, R., Koistinen, H., Seppala, M., Ho, P.C. and Chiu, P.C. (2006) Roles of glycodelin in modulating sperm function. Mol. Cell. Endocrinol., 25, 149-156, S0303-7207(05)00484-3 [pii] 10.1016/j.mce.2005.12.038.
    • (2006) Mol. Cell. Endocrinol. , vol.25 , pp. 149-156
    • Yeung, W.S.1    Lee, K.F.2    Koistinen, R.3    Koistinen, H.4    Seppala, M.5    Ho, P.C.6    Chiu, P.C.7
  • 32
    • 0033863867 scopus 로고    scopus 로고
    • Recombinant glycodelin carrying the same type of glycan structures as contraceptive glycodelin-A can be produced in human kidney 293 cells but not in Chinese hamster ovary cells
    • DOI 10.1046/j.1432-1327.2000.01528.x
    • Van den Nieuwenhof, I.M., Koistinen, H., Easton, R.L., Koistinen, R., Kamarainen, M., Morris, H.R., Van Die, I., Seppala, M., Dell, A. and Van den Eijnden, D.H. (2000) Recombinant glycodelin carrying the same type of glycan structures as contraceptive glycodelin-A can be produced in human kidney 293 cells but not in Chinese hamster ovary cells. Eur. J. Biochem., 267, 4753-4762, ejb1528 [pii]. (Pubitemid 30619466)
    • (2000) European Journal of Biochemistry , vol.267 , Issue.15 , pp. 4753-4762
    • Van Den Nieuwenhof, I.M.1    Koistinen, H.2    Easton, R.L.3    Koistinen, R.4    Kamarainen, M.5    Morris, H.R.6    Van Die, I.7    Seppala, M.8    Dell, A.9    Van Den Eijnden, D.H.10
  • 34
    • 0032078018 scopus 로고    scopus 로고
    • Expression, purification, crystallization and crystallographic characterization of the human MHC class I related protein MICA
    • DOI 10.1107/S0907444997015229
    • Bauer, S., Willie, S.T., Spies, T. and Strong, R.K. (1998) Expression, purification, crystallization and crystallographic characterization of the human MHC class I related protein MICA. Acta Crystallogr. D Biol. Crystallogr., 54, 451-453. (Pubitemid 28235867)
    • (1998) Acta Crystallographica Section D: Biological Crystallography , vol.54 , Issue.3 , pp. 451-453
    • Bauer, S.1    Willie, S.T.2    Spies, T.3    Strong, R.K.4
  • 35
    • 0035347169 scopus 로고    scopus 로고
    • Complex structure of the activating immunoreceptor NKG2D and its MHC class I-like ligand MICA
    • Li, P., Morris, D.L., Willcox, B.E., Steinle, A., Spies, T. and Strong, R.K. (2001) Complex structure of the activating immunoreceptor NKG2D and its MHC class I-like ligand MICA. Nat. Immunol., 2, 443-451, 10.1038/87757 87757 [pii]. (Pubitemid 33706143)
    • (2001) Nature Immunology , vol.2 , Issue.5 , pp. 443-451
    • Li, P.1    Morris, D.L.2    Willcox, B.E.3    Steinle, A.4    Spies, T.5    Strong, R.K.6
  • 36
    • 73849143129 scopus 로고    scopus 로고
    • Interactions between lipids and human anti-HIV antibody 4E10 can be reduced without ablating neutralizing activity
    • 10.1128/JVI.02113-09
    • Xu, H., Song, L., Kim, M., Holmes, M.A., Kraft, Z., Sellhorn, G., Reinherz, E.L., Stamatatos, L. and Strong, R.K. (2010) Interactions between lipids and human anti-HIV antibody 4E10 can be reduced without ablating neutralizing activity. J. Virol., 84, 1076-1088, 10.1128/JVI.02113-09.
    • (2010) J. Virol. , vol.84 , pp. 1076-1088
    • Xu, H.1    Song, L.2    Kim, M.3    Holmes, M.A.4    Kraft, Z.5    Sellhorn, G.6    Reinherz, E.L.7    Stamatatos, L.8    Strong, R.K.9
  • 37
    • 77955280009 scopus 로고    scopus 로고
    • Fighting cancers from within: Augmenting tumor immunity with cytokine therapy
    • 10.1016/j.tips.2010.05.003
    • Pellegrini, M., Mak, T.W. and Ohashi, P.S. (2010) Fighting cancers from within: augmenting tumor immunity with cytokine therapy. Trends Pharmacol. Sci., 31, 356-363, 10.1016/j.tips.2010.05.003.
    • (2010) Trends Pharmacol. Sci. , vol.31 , pp. 356-363
    • Pellegrini, M.1    Mak, T.W.2    Ohashi, P.S.3
  • 38
    • 75949102905 scopus 로고    scopus 로고
    • Use of cytokine therapy in primary immunodeficiency
    • 10.1007/s12016-009-8131-4
    • Roy-Ghanta, S. and Orange, J.S. (2010) Use of cytokine therapy in primary immunodeficiency. Clin. Rev. Allergy Immunol., 38, 39-53, 10.1007/s12016-009- 8131-4.
    • (2010) Clin. Rev. Allergy Immunol. , vol.38 , pp. 39-53
    • Roy-Ghanta, S.1    Orange, J.S.2
  • 39
    • 77953039728 scopus 로고    scopus 로고
    • Recombinant immunotherapeutics: Current state and perspectives regarding the feasibility and market
    • 10.1007/s00253-010-2590-7
    • Huang, C.-J., Lowe, A.J. and Batt, C.A. (2010) Recombinant immunotherapeutics: current state and perspectives regarding the feasibility and market. Appl. Microbiol. Biotechnol., 87, 401-410, 10.1007/s00253-010-2590-7.
    • (2010) Appl. Microbiol. Biotechnol. , vol.87 , pp. 401-410
    • Huang, C.-J.1    Lowe, A.J.2    Batt, C.A.3
  • 40
    • 18644361997 scopus 로고    scopus 로고
    • Pharmacokinetic and pharmacodynamic considerations in the development of therapeutic proteins
    • DOI 10.2165/00003088-200544040-00001
    • Mahmood, I. and Green, M.D. (2005) Pharmacokinetic and pharmacodynamic considerations in the development of therapeutic proteins. Clin. Pharmacokinetics, 44, 331-347. (Pubitemid 40663681)
    • (2005) Clinical Pharmacokinetics , vol.44 , Issue.4 , pp. 331-347
    • Mahmood, I.1    Green, M.D.2
  • 41
  • 42
    • 79955418828 scopus 로고    scopus 로고
    • Harnessing the biology of IL-7 for therapeutic application
    • 10.1038/nri2970
    • Mackall, C.L., Fry, T.J. and Gress, R.E. (2011) Harnessing the biology of IL-7 for therapeutic application. Nat. Rev. Immunol., 11, 330-342, 10.1038/nri2970.
    • (2011) Nat. Rev. Immunol. , vol.11 , pp. 330-342
    • MacKall, C.L.1    Fry, T.J.2    Gress, R.E.3
  • 43
    • 0031787370 scopus 로고    scopus 로고
    • Functions of the N-glycans of rat leukemia inhibitory factor expressed in chinese hamster ovary cells
    • Sasai, K., Aikawa, J.I., Saburi, S., Tojo, H., Tanaka, S., Ogawa, T. and Shiota, K. (1998) Functions of the N-glycans of rat leukemia inhibitory factor expressed in Chinese hamster ovary cells. J. Biochem., 124, 999-1003. (Pubitemid 28544912)
    • (1998) Journal of Biochemistry , vol.124 , Issue.5 , pp. 999-1003
    • Sasai, K.1    Aikawa, J.-I.2    Saburi, S.3    Tojo, H.4    Tanaka, S.5    Ogawa, T.6    Shiota, K.7
  • 44
    • 79951551289 scopus 로고    scopus 로고
    • A simple method for production and purification of soluble and biologically active recombinant human leukemia inhibitory factor (hLIF) fusion protein in Escherichia coli
    • 10.1016/j.jbiotec.2010.12.020
    • Imsoonthornruksa, S., Noisa, P., Parnpai, R. and Ketudat-Cairns, M. (2011) A simple method for production and purification of soluble and biologically active recombinant human leukemia inhibitory factor (hLIF) fusion protein in Escherichia coli. J. Biotechnol., 151, 295-302, 10.1016/j.jbiotec. 2010.12.020.
    • (2011) J. Biotechnol. , vol.151 , pp. 295-302
    • Imsoonthornruksa, S.1    Noisa, P.2    Parnpai, R.3    Ketudat-Cairns, M.4
  • 45
    • 67149099142 scopus 로고    scopus 로고
    • N-Myc regulates expression of pluripotency genes in neuroblastoma including lif, klf2, klf4, and lin28b
    • 10.1371/journal.pone.0005799
    • Cotterman, R. and Knoepfler, P.S. (2009) N-Myc regulates expression of pluripotency genes in neuroblastoma including lif, klf2, klf4, and lin28b. PLoS ONE, 4, e5799, 10.1371/journal.pone.0005799.
    • (2009) PLoS ONE , vol.4
    • Cotterman, R.1    Knoepfler, P.S.2
  • 46
    • 40549099294 scopus 로고    scopus 로고
    • Five decades of progress in haematopoietic cell transplantation based on the preclinical canine model
    • Lupu, M. and Storb, R. (2007) Five decades of progress in haematopoietic cell transplantation based on the preclinical canine model. Cancer Res., 5, 14-31.
    • (2007) Cancer Res. , vol.5 , pp. 14-31
    • Lupu, M.1    Storb, R.2
  • 47
    • 1542548082 scopus 로고    scopus 로고
    • Studies of cocktail therapy with multiple cytokines for neoplasia or infectious disease of the dog I. cDNA cloning of canine IL-3 and IL-6
    • Shin, I.S., Kim, H.R., Nam, M.J. and Youn, H.Y. (2001) Studies of cocktail therapy with multiple cytokines for neoplasia or infectious disease of the dog I. cDNA cloning of canine IL-3 and IL-6. J. Vet. Sci., 2, 115-120.
    • (2001) J. Vet. Sci. , vol.2 , pp. 115-120
    • Shin, I.S.1    Kim, H.R.2    Nam, M.J.3    Youn, H.Y.4
  • 48
    • 3042521098 scopus 로고    scopus 로고
    • Improved prediction of signal peptides: SignalP 3.0
    • DOI 10.1016/j.jmb.2004.05.028, PII S0022283604005972
    • Bendtsen, J.D., Nielsen, H., von Heijne, G. and Brunak, S. (2004) Improved prediction of signal peptides: SignalP 3.0. J. Mol. Biol., 340, 783-795, 10.1016/j.jmb.2004.05.028. (Pubitemid 38829638)
    • (2004) Journal of Molecular Biology , vol.340 , Issue.4 , pp. 783-795
    • Bendtsen, J.D.1    Nielsen, H.2    Von Heijne, G.3    Brunak, S.4
  • 49
    • 34547737420 scopus 로고    scopus 로고
    • Generation and characterization of stromal cell independent IL-7 dependent B cell lines
    • DOI 10.1016/j.jim.2007.05.010, PII S0022175907001603
    • Corfe, S.A., Gray, A.P. and Paige, C.J. (2007) Generation and characterization of stromal cell independent IL-7 dependent B cell lines. J. Immunol. Methods, 325, 9-19, 10.1016/j.jim.2007.05.010. (Pubitemid 47238287)
    • (2007) Journal of Immunological Methods , vol.325 , Issue.1-2 , pp. 9-19
    • Corfe, S.A.1    Gray, A.P.2    Paige, C.J.3
  • 50
    • 16844364151 scopus 로고    scopus 로고
    • LIF/STAT3 controls ES cell self-renewal and pluripotency by a Myc-dependent mechanism
    • DOI 10.1242/dev.01670
    • Cartwright, P., McLean, C., Sheppard, A., Rivett, D., Jones, K. and Dalton, S. (2005) LIF/STAT3 controls ES cell self-renewal and pluripotency by a Myc-dependent mechanism. Development, 132, 885-896, 10.1242/dev.01670. (Pubitemid 40484924)
    • (2005) Development , vol.132 , Issue.5 , pp. 885-896
    • Cartwright, P.1    McLean, C.2    Sheppard, A.3    Rivett, D.4    Jones, K.5    Dalton, S.6
  • 51
    • 33750344655 scopus 로고    scopus 로고
    • The CARMA1 signalosome links the signalling machinery of adaptive and innate immunity in lymphocytes
    • DOI 10.1038/nri1944, PII NRI1944
    • Rawlings, D.J., Sommer, K. and Moreno-Garcia, M.E. (2006) The CARMA1 signalosome links the signalling machinery of adaptive and innate immunity in lymphocytes. Nat. Rev. Immunol., 6, 799-812, 10.1038/nri1944. (Pubitemid 44631649)
    • (2006) Nature Reviews Immunology , vol.6 , Issue.11 , pp. 799-812
    • Rawlings, D.J.1    Sommer, K.2    Moreno-Garcia, M.E.3
  • 52
    • 28844500398 scopus 로고    scopus 로고
    • Phosphorylation of the CARMA1 linker controls NF-κB activation
    • DOI 10.1016/j.immuni.2005.09.014, PII S1074761305003109
    • Sommer, K., Guo, B., Pomerantz, J.L., Bandaranayake, A.D., Ovechkina, Y.L., Moreno-garci, M.E. and Rawlings, D.J. (2005) Phosphorylation of the CARMA1 linker controls NF-kB activation. Immunity, 23, 561-574, 10.1016/j.immuni.2005. 09.014. (Pubitemid 41779479)
    • (2005) Immunity , vol.23 , Issue.6 , pp. 561-574
    • Sommer, K.1    Guo, B.2    Pomerantz, J.L.3    Bandaranayake, A.D.4    Moreno-Garcia, M.E.5    Ovechkina, Y.L.6    Rawlings, D.J.7
  • 53
    • 38849148421 scopus 로고    scopus 로고
    • Monomer/dimer transition of the caspase-recruitment domain of human Nod1
    • DOI 10.1021/bi7016602
    • Srimathi, T., Robbins, S.L., Dubas, R.L., Hasegawa, M., Inohara, N. and Park, Y.C. (2008) Monomer/dimer transition of the caspase-recruitment domain of human Nod1. Biochemistry, 47, 1319-1325, 10.1021/bi7016602. (Pubitemid 351198708)
    • (2008) Biochemistry , vol.47 , Issue.5 , pp. 1319-1325
    • Srimathi, T.1    Robbins, S.L.2    Dubas, R.L.3    Hasegawa, M.4    Inohara, N.5    Young, C.P.6
  • 54
    • 0036865552 scopus 로고    scopus 로고
    • The neutrophil lipocalin NGAL is a bacteriostatic agent that interferes with siderophore-mediated iron acquisition
    • DOI 10.1016/S1097-2765(02)00708-6
    • Goetz, D.H., Holmes, M.A., Borregaard, N., Bluhm, M.E., Raymond, K.N. and Strong, R.K. (2002) The neutrophil lipocalin NGAL is a bacteriostatic agent that interferes with siderophore-mediated iron acquisition. Mol. Cell, 10, 1033-1043. (Pubitemid 36001971)
    • (2002) Molecular Cell , vol.10 , Issue.5 , pp. 1033-1043
    • Goetz, D.H.1    Holmes, M.A.2    Borregaard, N.3    Bluhm, M.E.4    Raymond, K.N.5    Strong, R.K.6
  • 55
    • 0031938562 scopus 로고    scopus 로고
    • Expression, purification, crystallization and crystallographic characterization of dimeric and monomeric human neutrophil gelatinase associated lipocalin (NGAL)
    • DOI 10.1107/S0907444997010615
    • Strong, R.K., Bratt, T., Cowland, J.B., Borregaard, N., Wiberg, F.C. and Ewald, A.J. (1998) Expression, purification, crystallization and crystallographic characterization of dimeric and monomeric human neutrophil gelatinase associated lipocalin (NGAL). Acta Crystallogr. Sect. D, Biol. Crystallogr., 54, 93-95. (Pubitemid 28111123)
    • (1998) Acta Crystallographica Section D: Biological Crystallography , vol.54 , Issue.1 , pp. 93-95
    • Strong, R.K.1    Bratt, T.2    Cowland, J.B.3    Borregaard, N.4    Wiberg, F.C.5    Ewald, A.J.6
  • 56
    • 0034728351 scopus 로고    scopus 로고
    • Ligand preference inferred from the structure of neutrophil gelatinase associated lipocalin
    • DOI 10.1021/bi992215v
    • Goetz, D.H., Willie, S.T., Armen, R.S., Bratt, T., Borregaard, N. and Strong, R.K. (2000) Ligand preference inferred from the structure of neutrophil gelatinase associated lipocalin. Society, 39, 1935-1941. (Pubitemid 30124000)
    • (2000) Biochemistry , vol.39 , Issue.8 , pp. 1935-1941
    • Goetz, D.H.1    Willie, S.T.2    Armen, R.S.3    Bratt, T.4    Borregaard, N.5    Strong, R.K.6
  • 57
    • 77952580752 scopus 로고    scopus 로고
    • Life and death of a BiP substrate
    • 10.1016/j.semcdb.2009.12.008
    • Otero, J.H., Lizák, B. and Hendershot, L.M. (2010) Life and death of a BiP substrate. Semin. Cell Dev. Biol., 21, 472-478, 10.1016/j.semcdb.2009. 12.008.
    • (2010) Semin. Cell Dev. Biol. , vol.21 , pp. 472-478
    • Otero, J.H.1    Lizák, B.2    Hendershot, L.M.3
  • 58
    • 26944481086 scopus 로고    scopus 로고
    • CpG-island fragments from the HNRPA2B1/CBX3 genomic locus reduce silencing and enhance transgene expression from the hCMV promoter/enhancer in mammalian cells
    • 10.1186/1472-675′-5-17
    • Williams, S., Mustoe, T., Mulcahy, T., Griffiths, M., Simpson, D., Antoniou, M., Irvine, A., Mountain, A. and Crombie, R. (2005) CpG-island fragments from the HNRPA2B1/CBX3 genomic locus reduce silencing and enhance transgene expression from the hCMV promoter/enhancer in mammalian cells. BMC Biotechnol., 5, 17, 10.1186/1472-675′-5-17.
    • (2005) BMC Biotechnol. , vol.5 , pp. 17
    • Williams, S.1    Mustoe, T.2    Mulcahy, T.3    Griffiths, M.4    Simpson, D.5    Antoniou, M.6    Irvine, A.7    Mountain, A.8    Crombie, R.9
  • 59
    • 0036422427 scopus 로고    scopus 로고
    • The use of UCOE vectors in combination with a preadapted serum free, suspension cell line allows for rapid production of large quantities of protein
    • DOI 10.1023/A:1021141712344
    • Benton, T., Chen, T., McEntee, M., Fox, B., King, D., Crombie, R., Thomas, T.C. and Bebbington, C. (2002) The use of UCOE vectors in combination with a preadapted serum free, suspension cell line allows for rapid production of large quantities of protein. Cytotechnology, 38, 43-46. (Pubitemid 35307407)
    • (2002) Cytotechnology , vol.38 , Issue.1-3 , pp. 43-46
    • Benton, T.1    Chen, T.2    McEntee, M.3    Fox, B.4    King, D.5    Crombie, R.6    Thomas, T.C.7    Bebbington, C.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.