Impact of vitamin A on clinical outcomes in haemodialysis patients

Nephrology Dialysis Transplantation

Volumn 26, Issue 12, 2011, Pages 4054-4061

  Espe, Katharina M ^a   Raila, Jens ^a   Henze, Andrea ^a   Krane, Vera ^b   Schweigert, Florian J ^a   Hocher, Berthold ^a,c,d   Wanner, Christoph ^b   Drechsler, Christiane ^b  

^a UNIVERSITY OF POTSDAM   (Germany)

^b UNIVERSITY OF WÜRZBURG   (Germany)

^c CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^d F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

haemodialysis; mortality; retinol; retinol binding protein 4; sudden death

Indexed keywords

ATORVASTATIN; PLACEBO; RETINOL; RETINOL BINDING PROTEIN 4;

ADULT; ADVERSE OUTCOME; AGED; ARTICLE; CARDIOVASCULAR RISK; CAUSE OF DEATH; COHORT ANALYSIS; CONTROLLED STUDY; CORRELATION ANALYSIS; DIABETIC PATIENT; DISEASE ASSOCIATION; DISEASE SEVERITY; FEMALE; HAZARD RATIO; HEART INFARCTION; HEMODIALYSIS PATIENT; HUMAN; INFECTION RISK; KIDNEY FAILURE; MAJOR CLINICAL STUDY; MALE; MORBIDITY; MORTALITY; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RISK ASSESSMENT; RISK FACTOR; STROKE; SUDDEN DEATH; TREATMENT DURATION; VITAMIN BLOOD LEVEL; VITAMIN METABOLISM;

AGED; FEMALE; HUMANS; MALE; RENAL DIALYSIS; VITAMIN A;

EID: 82255185535     PISSN: 09310509     EISSN: 14602385     Source Type: Journal    
DOI: 10.1093/ndt/gfr171     Document Type: Article

References (26)

1. K/DOQI clinical practice guidelines for cardiovascular disease in dialysis patients. Am J Kidney Dis 2005; 45: S1-S153
2. ERA-EDTA Registry. ERA-EDTA Registry 2005 Annual Report. Amsterdam, Netherlands: Academic Medical Center, Department of Medical Informatics; 2007
3. Kaneto H, Katakami N, Matsuhisa M et al. Role of reactive oxygen species in the progression of type 2 diabetes and atherosclerosis. Mediators Inflamm 2010; 2010: 453892
4. Roehrs M, Valentini J, Bulcao R et al. The plasma retinol levels as pro-oxidant/oxidant agents in haemodialysis patients. Nephrol Dial Transplant 2009; 24: 2212-2218
5. Vahlquist A, Peterson PA, Wibell L. Metabolism of the vitamin A transporting protein complex. I. Turnover studies in normal persons and in patients with chronic renal failure. Eur J Clin Invest 1973; 3: 352-362
6. Riccioni G, DOrazio N, Scotti L et al. Circulating plasma antioxidants, inflammatory markers and asymptomatic carotid atherosclerosis in end-stage renal disease patients: a case control study. Int J Immunpathol Pharmacol 2010; 23: 327-334
7. Connolly GM, Cunningham R, Maxwell AP et al. Decreased serum retinol is associated with increased mortality in renal transplant recipients. Clin Chem 2007; 53: 1841-1846 (Pubitemid 47509679)
8. Abahusain MA, Al-Nahedh NN. The biochemical status of vitamin A and alpha-tocopherol during different stages of renal disease and its relationship to diabetes. Saudi J Kidney Dis Transpl 2002; 13: 18-23
9. Henze A, Frey SK, Raila J et al. Evidence that kidney function but not type 2 diabetes determines retinol-bin'ding protein 4 serum levels. Diabetes 2008; 57: 3323-3326
10. Raila J, Henze A, Spranger J et al. Microalbuminuria is a major determinant of elevated plasma retinol-binding protein 4 in type 2 diabetic patients. Kidney Int 2007; 72: 505-511 (Pubitemid 47237617)
11. Cabre A, Lazaro I, Girona J et al. Retinol-binding protein 4 as a plasma biomarker of renal dysfunction and cardiovascular disease in type 2 diabetes. J Intern Med 2007; 262: 496-503 (Pubitemid 47404369)
12. Wanner C, Krane V, MarzWet al. Atorvastatin in patients with type 2 diabetes mellitus undergoing hemodialysis. N Engl J Med 2005; 353: 238-248 (Pubitemid 41058323)
13. Wanner C, Krane V, MarzWet al. Randomized controlled trial on the efficacy and safety of atorvastatin in patients with type 2 diabetes on hemodialysis (4D study): demographic and baseline characteristics. Kidney Blood Press Res 2004; 27: 259-266 (Pubitemid 39279330)
14. Schweigert FJ, Hurtienne A, Bathe K. Improved extraction procedure for carotenoids from human milk. Int J Vitam Nutr Res 2000; 70: 79-83 (Pubitemid 30388046)
15. Gerlach TH, Zile MH. Effect of retinoic acid and apo-RBP on serum retinol concentration in acute renal failure. FASEB J 1991; 5: 86-92 (Pubitemid 21892840)
16. Kalousova M, Kubena AA, Kostirova M et al. Lower retinol levels as an independent predictor of mortality in long-term hemodialysis patients: a prospective observational cohort study. Am J Kidney Dis 2010; 2010: 9
17. Kalantar-Zadeh K, Abbott KC, Salahudeen AK et al. Survival advantages of obesity in dialysis patients. Am J Clin Nutr 2005; 81: 543-554
18. Drechsler C, Krane V, Winkler K et al. Changes in adiponectin and the risk of sudden death, stroke, myocardial infarction, and mortality in hemodialysis patients. Kidney Int 2009; 76: 567-575
19. Stephensen CB. Vitamin A, infection, and immune function. Annu Rev Nutr 2001; 21: 167-192
20. Rosales FJ, Ritter SJ, Zolfaghari R et al. Effects of acute inflammation on plasma retinol, retinol-binding protein, and its mRNA in the liver and kidneys of vitamin A-sufficient rats. J Lipid Res 1996; 37: 962-971 (Pubitemid 26182330)
21. Schweigert FJ. Inflammation-induced changes in the nutritional biomarkers serum retinol and carotenoids. Curr Opin Clin Nutr Metab Care 2001; 4: 477-481 (Pubitemid 34755402)
22. Zimmermann J, Herrlinger S, Pruy A et al. Inflammation enhances cardiovascular risk and mortality in hemodialysis patients. Kidney Int 1999; 55: 648-658 (Pubitemid 29082891)
23. Ferre P. The biology of peroxisome proliferator-activated receptors: relationship with lipid metabolism and insulin sensitivity. Diabetes 2004; 53: S43-S50 (Pubitemid 38168692)
24. Cabrero A, Laguna JC, Vazquez M. Peroxisome proliferator-activated receptors and the control of inflammation. Curr Drug Targets Inflamm Allergy 2002; 1: 243-248
25. Nohara A, Kobayashi J, Mabuchi H. Retinoid X receptor heterodimer variants and cardiovascular risk factors. J Atheroscler Thromb 2009; 16: 303-318
26. Ingelsson E, Sundstrom J, Melhus H et al. Circulating retinol-binding protein 4, cardiovascular risk factors and prevalent cardiovascular disease in elderly. Atherosclerosis 2009; 206: 239-244