Multimodal photoacoustic and optical coherence tomography scanner using an all optical detection scheme for 3D morphological skin imaging

Biomedical Optics Express

Volumn 2, Issue 8, 2011, Pages 2202-2215

  Zhang, Edward Z ^a   Povazay, Boris ^b   Laufer, Jan ^a   Alex, Aneesh ^b   Hofer, Bernd ^b   Pedley, Barbara ^c   Glittenberg, Carl ^d   Treeby, Bradley ^a   Cox, Ben ^a   Beard, Paul ^a   Drexler, Wolfgang ^b  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b MEDICAL UNIVERSITY OF VIENNA   (Austria)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

^d KRANKENANSTALT RUDOLFSTIFTUNG   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

LASER RECORDING; PHOTOACOUSTIC EFFECT; POLYMER FILMS; SCANNING; SENSORS; THREE DIMENSIONAL; THREE DIMENSIONAL COMPUTER GRAPHICS; TISSUE; ULTRASONIC APPLICATIONS;

3D IMAGING; AXIAL RESOLUTIONS; BACKWARD MODES; FABRY-PEROT; FIELD OF VIEWS; HIGH RESOLUTION; HUMAN SKIN; IMAGING CONFIGURATIONS; IN-VIVO; IN-VIVO IMAGES; INFLAMMATORY CONDITIONS; LATERAL RESOLUTION; MULTI-MODAL; OPTICAL DETECTION SCHEMES; OPTICAL RESOLUTION; OPTICAL SCANNERS; PHOTO-ACOUSTIC IMAGING; PHOTOACOUSTIC EXCITATION; PHOTOACOUSTIC WAVE; POTENTIAL APPLICATIONS; PROBE BEAM; SENSOR HEAD; SKIN CONDITIONS; SKIN IMAGING; SOFT TISSUE; SPECTRAL RANGE; TISSUE ABNORMALITIES; TOMOGRAPHIC; ULTRASOUND SENSORS; VASCULAR LESIONS; VASCULAR STRUCTURES; VASCULATURE;

OPTICAL TOMOGRAPHY;

MURINAE;

EID: 82255174692     PISSN: None     EISSN: 21567085     Source Type: Journal    
DOI: 10.1364/BOE.2.002202     Document Type: Article

References (33)

1. P. C. Beard, "Biomedical photoacoustic imaging," Interface Focus 1, 602-631 (2011).
2. J. G. Laufer, D. T. Delpy, C. E. Elwell, and P. C. Beard, "Quantitative spatially resolved measurement of tissue chromophore concentrations using photoacoustic spectroscopy: application to the measurement of blood oxygenation and haemoglobin concentration," Phys. Med. Biol. 52(1), 141-168 (2007).
3. J. G. Laufer, B. Cox, E. Z. Zhang, and P. C. Beard, "Quantitative determination of chromophore concentrations from 2D photoacoustic images using a nonlinear model-based inversion scheme," Appl. Opt. 49(8), 1219-1233 (2010).
4. P. C. Beard, Flow velocity measurements, UK Patent Application, PCT/GB02/04977 (2001)
5. J. Brunker and P. C. Beard, "Pulsed photoacoustic Doppler flow measurements in blood-mimicking phantoms," Proc. SPIE 7899, 78991K, 78991K-10 (2011).
6. H. Fang, K. Maslov, and L. V. Wang, "Photoacoustic Doppler effect from flowing small light-absorbing particles," Phys. Rev. Lett. 99(18), 184501 (2007).
7. R. A. Kruger, R. B. Lam, D. R. Reinecke, S. P. Del Rio, and R. P. Doyle, "Photoacoustic angiography of the breast," Med. Phys. 37(11), 6096-6100 (2010).
8. X. Wang, Y. Pang, G. Ku, X. Xie, G. Stoica, and L. V. Wang, "Noninvasive laser-induced photoacoustic tomography for structural and functional in vivo imaging of the brain," Nat. Biotechnol. 21(7), 803-806 (2003).
9. J. G. Laufer, E. Z. Zhang, G. Raivich, and P. C. Beard, "Three-dimensional noninvasive imaging of the vasculature in the mouse brain using a high resolution photoacoustic scanner," Appl. Opt. 48(10), D299-D306 (2009).
10. C. Li, A. Aguirre, J. Gamelin, A. Maurudis, Q. Zhu, and L. V. Wang, "Real-time photoacoustic tomography of cortical hemodynamics in small animals," J. Biomed. Opt. 15(1), 010509 (2010).
11. H. P. Brecht, R. Su, M. Fronheiser, S. A. Ermilov, A. Conjusteau, and A. A. Oraevsky, "Whole-body three-dimensional optoacoustic tomography system for small animals," J. Biomed. Opt. 14(6), 064007 (2009).
12. E. Z. Zhang, J. G. Laufer, R. B. Pedley, and P. C. Beard, "In vivo high-resolution 3D photoacoustic imaging of superficial vascular anatomy," Phys. Med. Biol. 54(4), 1035-1046 (2009).
13. K. Maslov, H. F. Zhang, S. Hu, and L. V. Wang, "Optical-resolution photoacoustic microscopy for in vivo imaging of single capillaries," Opt. Lett. 33(9), 929-931 (2008).
14. C. Zhang, K. Maslov, and L. V. Wang, "Subwavelength-resolution label-free photoacoustic microscopy of optical absorption in vivo," Opt. Lett. 35(19), 3195-3197 (2010).
15. D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, "Optical coherence tomography," Science 254(5035), 1178-1181 (1991).
16. A. F. Fercher, C. K. Hitzenberger, W. Drexler, G. Kamp, and H. Sattmann, "In vivo optical coherence tomography," Am. J. Ophthalmol. 116(1), 113-114 (1993).
17. C. K. Fercher, C. K. Hitzenberger, G. Kamp, and S. Y. El-Zaiat, "Measurement of intraocular distances by backscattering spectral interferometry," Opt. Commun. 117, 43-48 (1995).
18. G. Häusler, J. M. Herrmann, R. Kummer, and M. W. Lindner, "Observation of light propagation in volume scatterers with 1011-fold slow motion," Opt. Lett. 21(14), 1087-1089 (1996).
19. S. R. Chinn, E. A. Swanson, and J. G. Fujimoto, "Optical coherence tomography using a frequency-tunable optical source," Opt. Lett. 22(5), 340-342 (1997).
20. R. K Wang, L. An, P. Francis, and D. J. Wilson, "Depth-resolved imaging of capillary networks in retina and choroid using ultrahigh sensitive optical microangiography," Opt. Lett. 35(9), 1467-1469 (2010).
21. B. J. Vakoc, R. M. Lanning, J. A. Tyrrell, T. P. Padera, L. A. Bartlett, T. Stylianopoulos, L. L. Munn, G. J. Tearney, D. Fukumura, R. K Jain, and B. E. Bouma, "Three-dimensional microscopy of the tumor microenvironment in vivo using optical frequency domain imaging," Nat. Med. 15(10), 1219-1223 (2009).
22. B. Hermann, B. Hofer, C. Meier, and W. Drexler, "Spectroscopic measurements with dispersion encoded full range frequency domain optical coherence tomography in single- and multilayered non-scattering phantoms," Opt. Express 17(26), 24162-24174 (2009).
23. L. Li, K Maslov, G. Ku, and L. V. Wang, "Three-dimensional combined photoacoustic and optical coherence microscopy for in vivo microcirculation studies," Opt. Express 17(19), 16450-16455 (2009).
24. S. Jiao, Z. Xie, H. F. Zhang, and C. A. Puliafito, "Simultaneous multimodal imaging with integrated photoacoustic microscopy and optical coherence tomography," Opt. Lett. 34(19), 2961-2963 (2009).
25. S. Jiao, M. Jiang, J. Hu, A. Fawzi, Q. Zhou, K. K Shung, C. A. Puliafito, and H. F. Zhang, "Photoacoustic ophthalmoscopy for in vivo retinal imaging," Opt. Express 18(4), 3967-3972 (2010).
26. E. Z. Zhang, J. G. Laufer, and P. C. Beard, "Backward-mode multiwavelength photoacoustic scanner using a planar Fabry-Perot polymer film ultrasound sensor for high-resolution three-dimensional imaging of biological tissues," Appl. Opt. 47(4), 561-577 (2008).
27. A. Alex, B. Považay, B. Hofer, S. Popov, C. Glittenberg, S. Binder, and W. Drexler, "Multispectral in vivo three-dimensional optical coherence tomography of human skin," J. Biomed. Opt. 15(2), 026025 (2010).
28. "Safety of laser products. Equipment classification, requirements and user's guide," BS EN60825-1 (The British Standard Institute, 1994)
29. K. P. Köstli, M. Frenz, H. Bebie, and H. P. Weber, "Temporal backward projection of optoacoustic pressure transients using fourier transform methods," Phys. Med. Biol. 46(7), 1863-1872 (2001).
30. P. A. Khavari, "Modelling cancer in human skin tissue," Nat. Rev. Cancer 6(4), 270-280 (2006).
31. B. E. Treeby, E. Z. Zhang, and B. T. Cox, "Photoacoustic tomography in absorbing acoustic media using time reversal," Inverse Probl. 26(11), 115003 (2010).
32. E. Z. Zhang, J. G. Laufer, P. C. Beard, B. Považay, A. Alex, B. Hofer, and W. Drexler, "Multimodal simultaneous photoacoustic tomography, optical resolution microscopy, and OCT system," Proc. SPIE 7564, 75640U, 75640U-7 (2010).
33. T. Liu, Q. Wei, J. Wang, S. Jiao, and H. F. Zhang, "Combined photoacoustic microscopy and optical coherence tomography can measure metabolic rate of oxygen," Biomed. Opt. Express 2(5), 1359-1365 (2011).