Toll-like receptor 4 engagement contributes to expression of NKG2D ligands by renal tubular epithelial cells

Nephrology Dialysis Transplantation

Volumn 26, Issue 12, 2011, Pages 3873-3881

  Chen, Gang Eric ^a   Wu, Huiling ^a   Ma, Jin ^a   Chadban, Steven J ^a   Sharland, Alexandra ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

Author keywords

HMGB1; innate immunity; ischaemia reperfusion injury; NKG2D; TLR4

Indexed keywords

HIGH MOBILITY GROUP B1 PROTEIN; HISTOCOMPATIBILITY 60; LIGAND; LIPOPOLYSACCHARIDE; MINERAL OIL; MURINE ULBP LIKE TRANSCRIPT 1; MYELOID DIFFERENTIATION FACTOR 88; NATURAL KILLER CELL RECEPTOR NKG2D; RETINOIC ACID INDUCIBLE PROTEIN I; TOLL LIKE RECEPTOR 4; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW; CELL ISOLATION; CELL STIMULATION; CONTROLLED STUDY; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; KIDNEY INJURY; KIDNEY ISCHEMIA; KIDNEY PARENCHYMA; KIDNEY TUBULE EPITHELIUM; MALE; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; REPERFUSION INJURY; SIGNAL TRANSDUCTION; UPREGULATION; WILD TYPE;

ANIMALS; EPITHELIAL CELLS; KIDNEY TUBULES; LIGANDS; MALE; MICE; NK CELL LECTIN-LIKE RECEPTOR SUBFAMILY K; NUCLEAR MATRIX-ASSOCIATED PROTEINS; NUCLEOCYTOPLASMIC TRANSPORT PROTEINS; TOLL-LIKE RECEPTOR 4; UROTHELIUM;

EID: 82255164272     PISSN: 09310509     EISSN: 14602385     Source Type: Journal    
DOI: 10.1093/ndt/gfr234     Document Type: Article

References (34)

1. Wu H, Chen G, Wyburn KR et al. TLR4 activation mediates kidney ischemia/reperfusion injury. J Clin Invest 2007; 117: 2847-2859 (Pubitemid 47529615)
2. Beg AA. Endogenous ligands of Toll-like receptors: implications for regulating inflammatory and immune responses. Trends Immunol 2002; 23: 509-512 (Pubitemid 35223541)
3. Schaefer L, Babelova A, Kiss E et al. The matrix component biglycan is proinflammatory and signals through Toll-like receptors 4 and 2 in macrophages. J Clin Invest 2005; 115: 2223-2233 (Pubitemid 41134165)
4. Tesar BM, Jiang D, Liang J et al. The role of hyaluronan degradation products as innate alloimmune agonists. Am J Transplant 2006; 6: 2622-2635 (Pubitemid 44571682)
5. Yu M, Wang H, Ding A et al. HMGB1 signals through toll-like receptor (TLR) 4 and TLR2. Shock 2006; 26: 174-179 (Pubitemid 44162504)
6. Tsung A, Hoffman RA, Izuishi K et al. Hepatic ischemia/reperfusion injury involves functional TLR4 signaling in nonparenchymal cells. J Immunol 2005; 175: 7661-7668 (Pubitemid 41713466)
7. Tsung A, Sahai R, Tanaka H et al. The nuclear factor HMGB1 mediates hepatic injury after murine liver ischemia-reperfusion. J Exp Med 2005; 201: 1135-1143 (Pubitemid 40524681)
8. Wu H, Ma J, Wang P et al. HMGB1 contributes to kidney ischemia reperfusion injury. J Am Soc Nephrol 2010. 21:1878-1890.
9. Anders HJ, Banas B, Schlondorff D. Signaling danger: toll-like receptors and their potential roles in kidney disease. J Am Soc Nephrol 2004; 15: 854-867 (Pubitemid 38375304)
10. Maasho K, Opoku-Anane J, Marusina AI et al. NKG2D is a costimulatory receptor for human naive CD81 T cells. J Immunol 2005; 174: 4480-4484
11. Roberts AI, Lee L, Schwarz E et al. NKG2D receptors induced by IL-15 costimulate CD28-negative effector CTL in the tissue microenvironment. J Immunol 2001; 167: 5527-5530 (Pubitemid 33062738)
12. Gilfillan S, Ho EL, Cella M et al. NKG2D recruits two distinct adapters to trigger NK cell activation and costimulation. Nat Immunol 2002; 3: 1150-1155 (Pubitemid 35469699)
13. Diefenbach A, Jensen ER, Jamieson AM et al. Rae1 and H60 ligands of the NKG2D receptor stimulate tumour immunity. Nature 2001; 413: 65-171
14. Groh V, Bahram S, Bauer S et al. Cell stress-regulated human major histocompatibility complex class I gene expressed in gastrointestinal epithelium. Proc Natl Acad Sci USA 1996; 93: 12445-12450 (Pubitemid 26367163)
15. Pende D, Rivera P, Marcenaro S et al. Major histocompatibility complex class I-related chain A and UL16-binding protein expression on tumor cell lines of different histotypes: analysis of tumor susceptibility to NKG2D-dependent natural killer cell cytotoxicity. Cancer Res 2002; 62: 6178-6186 (Pubitemid 35244469)
16. Nomura M, Zou Z, Joh T et al. Genomic structures and characterization of Rae1 family members encoding GPI-anchored cell surface proteins and expressed predominantly in embryonic mouse brain. J Biochem (Tokyo) 1996; 120: 987-995 (Pubitemid 26400022)
17. Feng L, Cheng F, Ye Z et al. The effect of renal ischemia-reperfusion injury on expression of RAE-1 and H60 in mice kidney. Transplant Proc 2006; 38: 2195-2198 (Pubitemid 46068461)
18. Zhang Z-X, Wang S, Huang X et al. NK cells induce apoptosis in tubular epithelial cells and contribute to renal iachemia-reperfusion injury. J Immunol 2008; 181: 7489-7498
19. Raulet DH. Roles of the NKG2D immunoreceptor and its ligands. Nat Rev Immunol 2003; 3: 781-790 (Pubitemid 37328656)
20. Hamerman JA, Ogasawara K, Lanier LL. Cutting edge: Toll-like receptor signaling in macrophages induces ligands for the NKG2D receptor. J Immunol 2004; 172: 2001
21. Yamada S, Inoue K, Yakabe K et al. High mobility group protein 1 (HMGB1) quantified by ELISA with a monoclonal antibody that does not cross-react with HMGB2. Clin Chem 2003; 49: 1535-1537 (Pubitemid 37011747)
22. Suda K, Kitagawa Y, Ozawa S et al. Anti-high-mobility group box chromosomal protein 1 antibodies improve survival of rats with sepsis. World J Surg 2006; 30: 1755-1762 (Pubitemid 44411235)
23. Abeyama K, Stern DM, Ito Y et al. The N-terminal domain of thrombomodulin sequesters high-mobility group-B1 protein, a novel antiinflammatory mechanism. J Clin Invest 2005; 115: 1267-1274 (Pubitemid 40629045)
24. Kim JY, Park JS, Strassheim D et al. HMGB1 contributes to the development of acute lung injury after hemorrhage. Am J Physiol Lung Cell Mol Physiol 2005; 288: L958-L965 (Pubitemid 40547924)
25. Sawa H, Ueda T, Takeyama Y et al. Blockade of high mobility group box-1 protein attenuates experimental severe acute pancreatitis. World J Gastroenterol 2006; 12: 7666-7670 (Pubitemid 46040580)
26. Wuthrich RP, Glimcher LH, Yui MA et al. MHC class II, antigen presentation and tumor necrosis factor in renal tubular epithelial cells. Kidney Int 1990; 37: 783-792 (Pubitemid 20056852)
27. Meldrum KK, Meldrum DR, Hile KL et al. A novel model of ischemia in renal tubular cells which closely parallels in vivo injury. J Surg Res 2001; 99: 288-293 (Pubitemid 32703448)
28. Wyburn K, Wu H, Yin J et al. Macrophage-derived interleukin-18 in experimental renal allograft rejection. Nephrol Dial Transplant 2005; 20: 699-706 (Pubitemid 40520645)
29. Jamieson AM, Diefenbach A, McMahon CW et al. The role of the NKG2D immunoreceptor in immune cell activation and natural killing. Immunity 2002; 17: 19-29 (Pubitemid 34874615)
30. Diefenbach A, Jamieson AM, Liu SD et al. Ligands for the murine NKG2D receptor: expression by tumor cells and activation of NK cells and macrophages. Nat Immunol 2000; 1: 119-126.
31. Ascon M, Ascon DB, Liu M et al. Renal ischemia-reperfusion leads to long term infiltration of activated and effector-memory T lymphocytes. Kidney Int 2009; 75: 526-535
32. Leemans JC, Stokman G, Claessen N et al. Renal-associated TLR2 mediates ischemia/reperfusion injury in the kidney. J Clin Invest 2005; 115: 2894-2903 (Pubitemid 41434417)
33. Van Beijnum JR, Buurman WA, Griffioen AW. Convergence and amplification of toll-like receptor (TLR) and receptor for advanced glycation end products (RAGE) signaling pathways via high mobility group B1 (HMGB1). Angiogenesis 2008; 1: 91-99
34. Wrenshall L. Role of the microenvironment in immune responses to transplantation. Springer Semin Immunopathol 2003; 25: 199-213 (Pubitemid 37130014)