Computed tomography findings in invasive pulmonary aspergillosis in non-neutropenic transplant recipients and neutropenic patients, and their prognostic value

Journal of Infection

Volumn 63, Issue 6, 2011, Pages 447-456

  Park, Seong Yeon ^a,b   Lim, Chaehun ^a   Lee, Sang Oh ^a   Choi, Sang Ho ^a   Kim, Yang Soo ^a   Woo, Jun Hee ^a   Song, Jae Woo ^a   Kim, Mi Young ^a   Chae, Eun Jin ^a   Do, Kyung Hyun ^a   Song, Koun Sik ^a   Seo, Joon Beom ^a   Kim, Sung Han ^a  

^a University of Ulsan College of Medicine   (South Korea)

^b Dongguk University Ilsan Hospital   (South Korea)

Author keywords

Invasive pulmonary aspergillosis; Neutropenic patients; Non neutropenic transplant recipients

Indexed keywords

AMPHOTERICIN B LIPID COMPLEX; GALACTOMANNAN; ITRACONAZOLE; MICAFUNGIN; VORICONAZOLE;

ACUTE GRAFT REJECTION; ADULT; ANTIGEN DETECTION; ARTICLE; AUTOLOGOUS HEMATOPOIETIC STEM CELL TRANSPLANTATION; CARBOHYDRATE ANALYSIS; CHEMOPROPHYLAXIS; CHRONIC GRAFT REJECTION; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; DISEASE ASSOCIATION; DRUG PULSE THERAPY; FEMALE; GRAFT VERSUS HOST REACTION; HUMAN; IMAGE ANALYSIS; IMMUNOSUPPRESSIVE TREATMENT; LUNG ASPERGILLOSIS; LUNG INFARCTION; LUNG NODULE; LUNG TRANSPLANTATION; MAJOR CLINICAL STUDY; MALE; MORTALITY; NEUTROPENIA; OUTCOME ASSESSMENT; PROGNOSIS; RETROSPECTIVE STUDY;

ADULT; FEMALE; HUMANS; INVASIVE PULMONARY ASPERGILLOSIS; LUNG; MALE; MIDDLE AGED; NEUTROPENIA; PROGNOSIS; RADIOGRAPHY, THORACIC; RETROSPECTIVE STUDIES; TOMOGRAPHY, X-RAY COMPUTED; TRANSPLANTATION;

EID: 82255162829     PISSN: 01634453     EISSN: 15322742     Source Type: Journal    
DOI: 10.1016/j.jinf.2011.08.007     Document Type: Article

References (32)

1. De Pauw B., Walsh T.J., Donnelly J.P., Stevens D.A., Edwards J.E., Calandra T., et al. Revised definitions of invasive fungal disease from the European organization for research and treatment of cancer/invasive fungal infections cooperative group and the national institute of allergy and infectious diseases mycoses study group (EORTC/MSG) consensus group. Clin Infect Dis 2008, 46(12):1813-1821.
2. Singh N., Paterson D.L. Aspergillus infections in transplant recipients. Clin Microbiol Rev 2005, 18(1):44-69.
3. Denning D.W. Therapeutic outcome in invasive aspergillosis. Clin Infect Dis 1996, 23(3):608-615.
4. Caillot D., Casasnovas O., Bernard A., Couaillier J.F., Durand C., Cuisenier B., et al. Improved management of invasive pulmonary aspergillosis in neutropenic patients using early thoracic computed tomographic scan and surgery. J Clin Oncol 1997, 15(1):139-147.
5. Wahba H., Truong M.T., Lei X., Kontoyiannis D.P., Marom E.M. Reversed halo sign in invasive pulmonary fungal infections. Clin Infect Dis 2008, 46(11):1733-1737.
6. Milito M.A., Kontoyiannis D.P., Lewis R.E., Liu P., Mawlawi O.R., Truong M.T., et al. Influence of host immunosuppression on ct findings in invasive pulmonary aspergillosis. Med Mycol 2010, 48(6):817-823.
7. Berenguer J., Allende M.C., Lee J.W., Garrett K., Lyman C., Ali N.M., et al. Pathogenesis of pulmonary aspergillosis. Granulocytopenia versus cyclosporine and methylprednisolone-induced immunosuppression. Am J Respir Crit Care Med 1995, 152(3):1079-1086.
8. Caillot D., Couaillier J.F., Bernard A., Casasnovas O., Denning D.W., Mannone L., et al. Increasing volume and changing characteristics of invasive pulmonary aspergillosis on sequential thoracic computed tomography scans in patients with neutropenia. J Clin Oncol 2001, 19(1):253-259.
9. Greene R.E., Schlamm H.T., Oestmann J.W., Stark P., Durand C., Lortholary O., et al. Imaging findings in acute invasive pulmonary aspergillosis: clinical significance of the halo sign. Clin Infect Dis 2007, 44(3):373-379.
10. Gerson S.L., Talbot G.H., Hurwitz S., Strom B.L., Lusk E.J., Cassileth P.A. Prolonged granulocytopenia: the major risk factor for invasive pulmonary aspergillosis in patients with acute leukemia. Ann Intern Med 1984, 100(3):345-351.
11. Orr D.P., Myerowitz R.L., Dubois P.J. Patho-radiologic correlation of invasive pulmonary aspergillosis in the compromised host. Cancer 1978, 41(5):2028-2039.
12. Park Y.S., Seo J.B., Lee Y.K., Do K.H., Lee J.S., Song J.W., et al. Radiological and clinical findings of pulmonary aspergillosis following solid organ transplant. Clin Radiol 2008, 63(6):673-680.
13. Park S.Y., Kim S.H., Choi S.H., Sung H., Kim M.N., Woo J.H., et al. Clinical and radiological features of invasive pulmonary aspergillosis in transplant recipients and neutropenic patients. Transpl Infect Dis 2010, 12(4):309-315.
14. Chamilos G., Luna M., Lewis R.E., Bodey G.P., Chemaly R., Tarrand J.J., et al. Invasive fungal infections in patients with hematologic malignancies in a tertiary care cancer center: an autopsy study over a 15-year period (1989-2003). Haematologica 2006, 91(7):986-989.
15. Kojima R., Tateishi U., Kami M., Murashige N., Nannya Y., Kusumi E., et al. Chest computed tomography of late invasive aspergillosis after allogeneic hematopoietic stem cell transplantation. Biol Blood Marrow Transplant 2005, 11(7):506-511.
16. Park S.Y., Lee S.O., Choi S.H., Sung H., Kim M.N., Choi C.M., et al. Aspergillus galactomannan antigen assay in bronchoalveolar lavage fluid for diagnosis of invasive pulmonary aspergillosis. J Infect 2010, 61(6):492-498.
17. Park S.Y., Lee S.O., Choi S.H., Jeong J.Y., Sung H., Kim M.N., et al. Serum and bronchoalveolar lavage fluid galactomannan assays in patients with pulmonary aspergilloma. Clin Infect Dis 2011, 52(7):e149-e152.
18. Woods G., Miceli M.H., Grazziutti M.L., Zhao W., Barlogie B., Anaissie E. Serum aspergillus galactomannan antigen values strongly correlated with outcome of invasive aspergillosis. A study of 56 patients with hematologic cancer. Cancer 2007, 110:830-834.
19. Maertens J., Buvé K., Theunissen K., Meersseman W., Verbeken E., Verhoef G., et al. Galactomaannan serves as surrogate endpoint for outcome of pulmonary invasive aspergillosis in neutropenic hematology patients. Cancer 2009, 115:355-362.
20. Hansell D.M., Bankier A.A., MacMahon H., McLoud T.C., Muller N.L., Remy J. Fleischner society: glossary of terms for thoracic imaging. Radiology 2008, 246(3):697-722.
21. Logan P.M., Primack S.L., Miller R.R., Muller N.L. Invasive aspergillosis of the airways: Radiographic, CT, and pathologic findings. Radiology 1994, 193(2):383-388.
22. Logan P.M., Muller N.L. High-resolution computed tomography and pathologic findings in pulmonary aspergillosis: a pictorial essay. Can Assoc Radiol J 1996, 47(6):444-452.
23. Stergiopoulou T., Meletiadis J., Roilides E., Kleiner D.E., Schaufele R., Roden M., et al. Host-dependent patterns of tissue injury in invasive pulmonary aspergillosis. Am J Clin Pathol 2007, 127(3):349-355.
24. Ascioglu S., Rex J.H., de Pauw B., Bennett J.E., Bille J., Crokaert F., et al. Defining opportunistic invasive fungal infections in immunocompromised patients with cancer and hematopoietic stem cell transplants: an international consensus. Clin Infect Dis 2002, 34(1):7-14.
25. Neofytos D. Chest computed tomography versus serm galactomannan enzyme immunoassay for the diagnosis of probable invasive pulmonary aspergillosis: to be decided. Clin Infect Dis 2010, 51(11):1281-1283.
26. Nucci M., Nouer S.A., Grazziutti M., Kumar N.S., Barlogie B., Anaissie E. Probable invasive aspergillosis without prespecified radiologic findings: Proposal for inclusion of a new category of aspergillosis and implications for studying novel therapies. Clin Infect Dis 2010, 51(11):1273-1280.
27. Baddley J.W., Andes D.R., Marr K.A., Kontoyiannis D.P., Alexander B.D., Kauffman C.A., et al. Factors associated with mortality in transplant patients with invasive aspergillosis. Clin Infect Dis 2010, 50(12):1559-1567.
28. Horger M., Hebart H., Einsele H., Lengerke C., Claussen C.D., Vonthein R., et al. Initial CT manifestations of invasive pulmonary aspergillosis in 45 non-hiv immunocompromised patients: association with patient outcome?. Eur J Radiol 2005, 55(3):437-444.
29. Hidalgo A., Parody R., Martino R., Sánchez F., Franquet T., Giménez A., et al. Correlation between high-resolution computed tomography and galactomannan antigenemia in adult hematologic patients at risk for invasive aspergillosis. Eur J Radiol 2009, 71(1):55-60.
30. Lewis R.E., Kontoyiannis D.P. Invasive aspergillosis in glucocorticoid-treated patients. Med Mycol 2009, 47(Suppl 1):S271-S281.
31. Cornillet A., Camus C., Nimubona S., Gandemer V., Tattevin P., Belleguic C., et al. Comparison of epidemiological, clinical, and biological features of invasive aspergillosis in neutropenic and nonneutropenic patients: a 6-year survey. Clin Infect Dis 2006, 43(5):577-584.
32. Husain S., Mooney M.L., Danziger-Isakov L., Mattner F., Singh N., Avery R., et al. A 2010 working formulation for the standardization of definitions of infections in cardiothoracoc transplant recipients. J Heart Lung Transplant 2011, 30(4):361-374.