Estradiol plus drospirenone therapy increases mammographic breast density in perimenopausal women

European Journal of Obstetrics and Gynecology and Reproductive Biology

Volumn 159, Issue 2, 2011, Pages 384-387

  Kiran, Hakan ^a   Tok, Abdullah ^b   Yüksel, Mürvet ^a   Arikan, Deniz Cemgil ^a   Ekerbicer, Hasan Cetin ^a  

^a KAHRAMANMARAS SUTCU IMAM UNIVERSITY   (Turkey)

^b State Hospital   (Turkey)

Author keywords

Breast density; Drospirenone; Estradiol; Mammography

Indexed keywords

DROSPIRENONE PLUS ESTRADIOL;

ADULT; ARTICLE; BODY MASS; BREAST DENSITY; CLIMACTERIUM; CLINICAL ARTICLE; CONTROLLED STUDY; DENSITY; FEMALE; HUMAN; MAMMOGRAPHY; MENARCHE; OLIGOMENORRHEA; PRIORITY JOURNAL; PROSPECTIVE STUDY; TREATMENT DURATION;

EID: 82255162709     PISSN: 03012115     EISSN: 18727654     Source Type: Journal    
DOI: 10.1016/j.ejogrb.2011.09.023     Document Type: Article

References (30)

1. N.F. Boyd, J. Stone, and L.J. Martin The association of breast mitogens with mammographic densities Br J Cancer 87 2002 876 882
2. J.N. Wolfe Risk for breast cancer development determined by mammographic parenchymal pattern Cancer 37 1976 2486 2492
3. N.F. Boyd, J.W. Byng, and R.A. Jong Quantitative classification of mammographic densities and breast cancer risk: results from the Canadian National Breast Screening Study J Natl Cancer Inst 87 1995 670 675
4. C. Byrne, C. Schairer, and J. Wolfe Mammographic features and breast cancer risk: effects with time, age, and menopause status J Natl Cancer Inst 87 1995 1622 1629
5. A.R. Genazzani, and T. Simoncini Timing is everything Gynecol Endocrinol 23 2007 1 4
6. W.H. Utian, D. Shoupe, G. Bachmann, J.V. Pinkerton, and J.H. Pickar Relief of vasomotor symptoms and vaginal atrophy with lower doses of conjugated equine estrogens and medroxyprogesterone acetate Fertil Steril 75 2001 1065 1079
7. P.R. Figueroa-Casas, B. Ettinger, E. Delgado, A. Javkin, and C. Vieder Reversal by medical treatment of endometrial hyperplasia caused by estrogen replacement therapy Menopause 8 2001 420 423
8. G.A. Greendale, B.A. Reboussin, and A. Sie Effects of estrogen and estrogen-progestin on mammographic parenchymal density. Postmenopausal Estrogen/Progestin Interventions (PEPI) Investigators Ann Intern Med 130 1999 262 269
9. A. McTiernan, C.F. Martin, and J.D. Peck Estrogen-plus-progestin use and mammographic density in postmenopausal women: women's health initiative randomized trial J Natl Cancer Inst 97 2005 1366 1376
10. E. Banks Hormone replacement therapy and the sensitivity and specificity of breast cancer screening: a review J Med Screen 8 2001 29 34
11. J. Warwick, E. Pinney, and R.M. Warren Breast density and breast cancer risk factors in a high-risk population Breast 12 2003 10 16
12. C. Panoulis, I. Lambrinoudaki, and A. Vourtsi Progestin may modify the effect of low-dose hormone therapy on mammographic breast density Climacteric 12 2009 240 247
13. W. Oelkers, J.M. Foidart, N. Dombrovicz, A. Welter, and R. Heithecker Effects of a new oral contraceptive containing an antimineralocorticoid progestogen, drospirenone, on the renin-aldosterone system, body weight, blood pressure, glucose tolerance, and lipid metabolism J Clin Endocrinol Metab 80 1995 1816 1821
14. R. Krattenmacher Drospirenone: pharmacology and pharmacokinetics of a unique progestogen Contraception 62 2000 29 38
15. R. Sitruk-Ware Pharmacology of different progestogens: the special case of drospirenone Climacteric 8 2005 4 12
16. M. Nielsen, P.C. Pettersen, and P. Alexandersen Breast density changes associated with postmenopausal hormone therapy: post hoc radiologist- and computer-based analyses Menopause 17 2010 772 778
17. V.A. McCormack, and I. dos Santos Silva Breast density and parenchymal patterns as markers of breast cancer risk: a meta-analysis Cancer Epidemiol Biomarkers Prev 15 2006 1159 1169
18. N.F. Boyd, J. Stone, L. Martin, S. Minkin, and M. Yaffe Mammographic densities and the growth hormone-IGF-1 prolactin axis Proc Am Assoc Cancer Res 42 2001 558
19. N. Boyd, L. Martin, J. Stone, L. Little, S. Minkin, and M. Yaffe A longitudinal study of the effects of menopause on mammographic features Cancer Epidemiol Biomarkers Prev 11 2002 1048 1053
20. J. Brisson, C. Diorio, and B. Mâsse Wolfe's parenchymal pattern and percentage of the breast with mammographic densities: redundant or complementary classifications? Cancer Epidemiol Biomarkers Prev 12 2003 728 732
21. G. Torres-Mejía, B. De Stavola, and D.S. Allen Mammographic features and subsequent risk of breast cancer: a comparison of qualitative and quantitative evaluations in the Guernsey prospective studies Cancer Epidemiol Biomarkers Prev 14 2005 1052 1059
22. L. Speroff The meaning of mammographic density in users of postmenopausal hormone therapy Maturitas 41 2002 171 175
23. H. Wang, N. Bjurstam, and H. Bjorndal Interval cancers in the Norwegian Breast Cancer Screening Program: frequency, characteristics and use of HRT Int J Cancer 94 2001 594 598
24. J.A. Harvey, J.V. Pinkerton, and C.R. Herman Short-term cessation of hormone replacement therapy and improvement of mammographic specificity J Natl Cancer Inst 89 1997 1623 1625
25. A.E. Schindler, C. Campagnoli, and R. Druckmann Classification and pharmacology of progestins Maturitas 46 2003 7 16
26. C. Otto, I. Fuchs, and H. Altmann Comparative analysis of the uterine and mammary gland effects of drospirenone and medroxyprogesterone acetate Endocrinology 149 2008 3952 3959
27. S. Carranza-Lira Safety, efficacy and patient acceptability of drospirenone and estradiol in the treatment of menopausal vasomotor symptoms: a review Clin Interv Aging 4 2009 59 62
28. J.M. Cline, G. Soderqvist, E. von Schoultz, L. Skoog, and B. von Schoultz Effects of hormone replacement therapy on the mammary gland of surgically postmenopausal cynomolgus macaques Am J Obstet Gynecol 174 1996 93 100
29. L.J. Hofseth, A.M. Raafat, J.R. Osuch, D.R. Pathak, C.A. Slomski, and S.Z. Halsam Hormone replacement therapy with estrogen or estrogen plus medroxyprogesterone acetate is associated with increase epithelial proliferation in the normal postmenopausal breast J Clin Endocrinol Metab 84 1999 4559 4565
30. T.A. Longacre, and S.A. Bartow A correlative morphologic study of the human breast and endothelium in the menstrual cycle Am J Surg Pathol 10 1986 362 393