Effects of three-monthly oral 150,000 IU cholecalciferol supplementation on falls, mobility, and muscle strength in older postmenopausal women: A randomized controlled trial

Journal of Bone and Mineral Research

Volumn 27, Issue 1, 2012, Pages 170-176

  Glendenning, Paul ^a,b,c   Zhu, Kun ^a,d   Inderjeeth, Charles ^a,e   Howat, Peter ^f   Lewis, Joshua R ^a,d   Prince, Richard L ^a,d  

^a UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^b UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^c ROYAL PERTH HOSPITAL   (Australia)

^d SIR CHARLES GAIRDNER HOSPITAL   (Australia)

^e Area Rehabilitation and Aged Care   (Australia)

^f CURTIN UNIVERSITY   (Australia)

Author keywords

CHOLECALCIFEROL SUPPLEMENTATION; FALLS; MOBILITY; MUSCLE STRENGTH; OLDER WOMEN

Indexed keywords

25 HYDROXYVITAMIN D; CALCIUM; COLECALCIFEROL; PLACEBO;

AGED; ARTICLE; CONTROLLED STUDY; DIETARY INTAKE; DOUBLE BLIND PROCEDURE; FALLING; FEMALE; HUMAN; MUSCLE STRENGTH; PHYSICAL MOBILITY; PHYSICAL PERFORMANCE; POSTMENOPAUSE; RANDOMIZED CONTROLLED TRIAL; VITAMIN BLOOD LEVEL; VITAMIN SUPPLEMENTATION;

ACCIDENTAL FALLS; ADMINISTRATION, ORAL; AGED; CALCIUM; CHOLECALCIFEROL; DIETARY SUPPLEMENTS; DRUG ADMINISTRATION SCHEDULE; FEMALE; HUMANS; LIFE STYLE; MOVEMENT; MUSCLE STRENGTH; POSTMENOPAUSE; VITAMIN D;

EID: 82155202612     PISSN: 08840431     EISSN: 15234681     Source Type: Journal    
DOI: 10.1002/jbmr.524     Document Type: Article

References (19)

1. Tinetti ME, Speechley M, Ginter SF,. Risk factors for falls among elderly persons living in the community. N Engl J Med. 1988; 319 (26): 1701-7. (Pubitemid 19019577)
2. Lord SR, Ward JA, Williams P, Anstey KJ,. Physiological factors associated with falls in older community-dwelling women. J Am Geriatr Soc. 1994; 42 (10): 1110-7. (Pubitemid 24309824)
3. Bischoff-Ferrari HA, Orav EJ, Dawson-Hughes B,. Effect of cholecalciferol plus calcium on falling in ambulatory older men and women: a 3-year randomized controlled trial. Arch Intern Med. 2006; 166 (4): 424-30.
4. Chapuy MC, Arlot ME, Duboeuf F, Brun J, Crouzet B, Arnaud S, Delmas PD, Meunier PJ,. Vitamin D3 and calcium to prevent hip fractures in elderly women. N Engl J Med. 1992; 327 (23): 1637-42.
5. Bischoff-Ferrari HA, Willett WC, Wong JB, Stuck AE, Staehelin HB, Orav EJ, Thoma A, Kiel DP, Henschkowski J,. Prevention of nonvertebral fractures with oral vitamin D and dose dependency: a meta-analysis of randomized controlled trials. Arch Intern Med. 2009; 169 (6): 551-61.
6. Prince RL, Austin N, Devine A, Dick IM, Bruce D, Zhu K,. Effects of ergocalciferol added to calcium on the risk of falls in elderly high-risk women. Arch Intern Med. 2008; 168 (1): 103-8.
7. Tang BM, Eslick GD, Nowson C, Smith C, Bensoussan A,. Use of calcium or calcium in combination with vitamin D supplementation to prevent fractures and bone loss in people aged 50 years and older: a meta-analysis. Lancet. 2007; 370 (9588): 657-66. (Pubitemid 47285316)
8. Trivedi DP, Doll R, Khaw KT,. Effect of four monthly oral vitamin D3 (cholecalciferol) supplementation on fractures and mortality in men and women living in the community: randomised double blind controlled trial. BMJ. 2003; 326 (7387): 469.
9. Wigg AE, Prest C, Slobodian P, Need AG, Cleland LG,. A system for improving vitamin D nutrition in residential care. Med J Aust. 2006; 185 (4): 195-8. (Pubitemid 44322780)
10. Sanders KM, Stuart AL, Williamson EJ, Simpson JA, Kotowicz MA, Young D, Nicholson GC,. Annual high-dose oral vitamin D and falls and fractures in older women: a randomized controlled trial. JAMA. 2010; 303 (18): 1815-22.
11. Podsiadlo D, Richardson S,. The timed "Up & Go": a test of basic functional mobility for frail elderly persons. J Am Geriatr Soc. 1991; 39 (2): 142-8.
12. Prince R, Devine A, Dick I, Criddle A, Kerr D, Kent N, Price R, Randell A,. The effects of calcium supplementation (milk powder or tablets) and exercise on bone density in postmenopausal women. J Bone Miner Res. 1995; 10 (7): 1068-75.
13. Prince RL, Devine A, Dhaliwal SS, Dick IM,. Effects of calcium supplementation on clinical fracture and bone structure: results of a 5-year, double-blind, placebo-controlled trial in elderly women. Arch Intern Med. 2006; 166 (8): 869-75.
14. Britt H,. A new coding tool for computerised clinical systems in primary care-ICPC plus. Aust Fam Physician. 1997; 26 (Suppl 2): S79-82.
15. Bischoff-Ferrari HA, Dawson-Hughes B, Staehelin HB, Orav JE, Stuck AE, Theiler R, Wong JB, Egli A, Kiel DP, Henschkowski J,. Fall prevention with supplemental and active forms of vitamin D: a meta-analysis of randomised controlled trials. BMJ. 2009; 339: b3692.
16. Smith H, Anderson F, Raphael H, Maslin P, Crozier S, Cooper C,. Effect of annual intramuscular vitamin D on fracture risk in elderly men and women-a population-based, randomized, double-blind, placebo-controlled trial. Rheumatology (Oxford). 2007; 46 (12): 1852-7. (Pubitemid 350168304)
17. DIPART (Vitamin D Individual Patient Analysis of Randomized Trials) Group. Patient level pooled analysis of 68 500 patients from seven major vitamin D fracture trials in US and Europe. BMJ. 2010; 340: b5463.
18. Neer RM, Arnaud CD, Zanchetta JR, Prince R, Gaich GA, Reginster JY, Hodsman AB, Eriksen EF, Ish-Shalom S, Genant HK, Wang O, Mitlak BH,. Effect of parathyroid hormone (1-34) on fractures and bone mineral density in postmenopausal women with osteoporosis. N Engl J Med. 2001; 344 (19): 1434-1.
19. Inderjeeth CA, Chan K, Glendenning P,. Teriparatide: its use in the treatment of osteoporosis. Clin Med Insights Ther. 2011; 3: 67-80.