Is CAG sequence length in the androgen receptor gene correlated with finger-length ratio?

Personality and Individual Differences

Volumn 52, Issue 2, 2012, Pages 224-227

  Loehlin, John C ^a   Medland, Sarah E ^b   Martin, Nicholas G ^b  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^b QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

Author keywords

2D:4D; Androgen receptor; Finger length ratio

Indexed keywords

EID: 81955164794     PISSN: 01918869     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.paid.2011.09.009     Document Type: Article

References (23)

1. Almasry S.M., El Domiaty M.A., Algaidi S.A., Elbastawisy Y.M., Safwat M.D. Index to ring digit ratio in Saudi Arabia at Almadinah Almonawahrah province: A direct and indirect measurement study. Journal of Anatomy 2011, 218:202-208.
2. Beatona A.A., Rudlinga N., Kisslinga C., Tourinesa R., Thomea J. Digit ratio (2D:4D), salivary testosterone, and handedness. Laterality 2011, 16:136-155.
3. Bennett M., Manning J.T., Cook C.J., Kilduff L.P. Digit ratio (2D:4D) and performance in elite rugby players. Journal of Sports Sciences 2011, 28:1415-1421.
4. Berenbaum S.A., Bryk K.K., Nowak N., Quigley C.A., Moffat S. Fingers as a marker of prenatal androgen exposure. Endocrinology 2009, 150:5119-5124.
5. Breedlove S.M. Minireview: Organizational hypotheses: Instances of the finger-post. Endocrinology 2010, 151:4116-4122.
6. Chamberlain N.L., Driver E.D., Miesfield R.L. The length and location of CAG trinucleotide in the androgen receptor N-terminal domain affects transactivation function. Nucleic Acids Research 1994, 22:3181-3186.
7. Ewen K.R., Bahlo M., Treloar S.A., Levinson D.F., Mowry B., Barlow J.W., et al. Identification and analysis of error types in high-throughput genotyping. American Journal of Human Genetics 2000, 67:727-736.
8. Hönekopp J., Bartholdt L., Beier L., Liebert A. Second to fourth digit length ratio (2D:4D) and adult sex hormone levels: New data and a meta-analytic review. Psychoneuroendocrinology 2007, 32:313-321.
9. Hönekopp J., Watson S. Meta-analysis of digit ratio 2D:4D shows greater sex difference in the right hand. American Journal of Human Biology 2010, 22:619-630.
10. Hurd P.L., Vaillancourt K.L., Dinsdale N.L. Aggression, digit ratio, and variation in androgen receptor and monoamine oxidase A genes in men. Behavior Genetics 2011, 41:543-566.
11. Ioannidis J.P.A., Trikalinos T.A. Early extreme contradictory estimates may appear in published results: The Proteus phenomenon in molecular genetics research and randomized trials. Journal of Clinical Epidemiology 2005, 58:543-549.
12. Knickmeyer R.C., Woolson S., Hamer R.M., Konneker T., Gilmore J.H. 2D:4D ratios in the first 2 years of life: Stability and relation to testosterone exposure and sensitivity. Hormones and Behavior 2011, 60:256-263.
13. Loehlin J.C., Medland S.E., Martin N.G. Relative finger lengths, sex differences, and psychological traits. Archives of Sexual Behavior 2009, 38:298-305.
14. Loehlin J.C., Medland S.E., Montgomery G.W., Martin N.G. Eysenck's Psychoticism and the X-linked androgen receptor gene CAG polymorphism in additional Australian samples. Personality and Individual Differences 2005, 39:661-667.
15. Manning J.T., Bundred P.E., Newton D.A., Flanagan B.F. The second to fourth finger ratio and variation in the androgen receptor gene. Evolution and Human Behavior 2003, 24:399-405.
16. Manning J.T., Fink B., Neave N., Caswell N. Photocopies yield lower digit ratios (2D:4D) than direct finger measurements. Archives of Sexual Behavior 2005, 34:329-333.
17. Manning J.T., Peters M. Digit ratio (2D:4D) and hand preference for writing in the BBC Internet Study. Laterality 2009, 14:528-540.
18. Medland S.E., Zayats T., Glaser B., Nyholt D.R., Gordon S.D., Wright M.J., et al. A variant in LIN28B is associated with 2D:4D finger-length ratio, a putative retrospective biomarker of prenatal testosterone exposure. American Journal of Human Genetics 2010, 86:519-525.
19. van Honk J., Schutter D.J., Bos P.A., Kruijt A.-W., Lentjes E.G., Baron-Cohen S. Testosterone administration impairs cognitive empathy in women depending on second-to-fourth digit ratio. Proceedings of the National Academy of Sciences 2011, 108:3448-3452.
20. Voracek M., Dressler S.G. High (feminized) digit ratio (2D:4D) in Danish men: A question of measurement method?. Human Reproduction 2006, 21:1329-1331.
21. Voracek M., Reimer B., Ertl C., Dressler S.G. Digit ratio (2D:4D), lateral preferences, and performance in fencing. Perceptual and Motor Skills 2006, 103:427-446.
22. Wright M.J., Martin N.G. The Brisbane Adolescent Twin Study: Outline of study methods and research projects. Australian Journal of Personality 2004, 56:65-78.
23. Zhu G., Evans D.M., Duffy D.L., Montgomery G.W., Medland S.E., Gillespie N.A., et al. A genome scan for eye colour in 502 twin families: Most variation is due to a QTL on chromosome 15q. Twin Research 2004, 7(2):197-210.