A double antigen bridging immunogenicity ELISA for the detection of antibodies to polyethylene glycol polymers

Journal of Pharmacological and Toxicological Methods

Volumn 64, Issue 3, 2011, Pages 238-245

  Liu, Yijuan ^a   Reidler, Helen ^a   Pan, Jing ^a   Milunic, David ^a   Qin, Dujie ^a   Chen, Dave ^a   Vallejo, Yli Remo ^a   Yin, Ray ^a  

^a ANP Technologies Inc   (United States)

Author keywords

Anti drug antibodies; Anti PEG antibodies; Bridging immunogenicity ELISA; PEGylated biotherapeutics; Universal PEG immunogenicity test method

Indexed keywords

MACROGOL;

ANTIBODY DETECTION; ANTIBODY LABELING; ANTIBODY SPECIFICITY; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; DRUG TOLERANCE; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; IMMUNOGENICITY; LIMIT OF DETECTION; MOLECULAR WEIGHT; PARTICLE SIZE; PROCESS DEVELOPMENT; REPRODUCIBILITY;

ANTIBODIES; ANTIBODIES, ANTI-IDIOTYPIC; ANTIGENS; DRUG CARRIERS; DRUG TOLERANCE; ENZYME-LINKED IMMUNOSORBENT ASSAY; HAPTENS; HUMANS; POLYETHYLENE; POLYETHYLENE GLYCOLS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SERUM;

ARMORACIA RUSTICANA;

EID: 81955164783     PISSN: 10568719     EISSN: 1873488X     Source Type: Journal    
DOI: 10.1016/j.vascn.2011.07.003     Document Type: Article

References (9)

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