Increase of paradoxical excitement response during propofol-induced sedation in hazardous and harmful alcohol drinkers

British Journal of Anaesthesia

Volumn 107, Issue 6, 2011, Pages 930-933

  Jeong, S ^a   Lee, H G ^a   Kim, W M ^a   Jeong, C W ^a   Lee, S H ^a   Yoon, M H ^a   Choi, J I ^a  

^a Chonnam National University Medical School   (South Korea)

Author keywords

alcohol; anaesthetics i.v., propofol; paradoxical excitement; sedation

Indexed keywords

ALCOHOL; PROPOFOL;

ADULT; ALCOHOL ABUSE; ARTICLE; BISPECTRAL INDEX; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRINKING BEHAVIOR; DRUG ACTIVITY; DRUG EFFECT; EXCITEMENT; FEMALE; HUMAN; INCIDENCE; KNEE; KNEE SURGERY; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SEDATION;

EID: 81855206565     PISSN: 00070912     EISSN: 14716771     Source Type: Journal    
DOI: 10.1093/bja/aer275     Document Type: Article

References (21)

1. Litchfield NB. Complications of intravenous diazepam-adverse psychological reactions. (An assessment of 16,000 cases). Anesth Prog 1980; 27: 175-83
2. Ibrahim AE, Taraday JK, Kharasch ED. Bispectral index monitoring during sedation with sevoflurane, midazolam, and propofol. Anesthesiology 2001; 95: 1151-9
3. Mancuso CE, Tanzi MG, Gabay M. Paradoxical reactions to benzodiazepines: literature review and treatment options. Pharmacotherapy 2004; 24: 1177-85
4. Rodrigo MR, Jonsson E. Conscious sedation with propofol. Br Dent J 1989; 166: 75-80
5. Massanari M, Novitsky J, Reinstein LJ. Paradoxical reactions in children associated with midazolam use during endoscopy. Clin Pediatr (Phila) 1997; 36: 681-4
6. Rodrigo CR. Flumazenil reverses paradoxical reaction with midazolam. Anesth Prog 1991; 38: 65-8
7. Honan VJ. Paradoxical reaction to midazolam and control with flumazenil. Gastrointest Endosc 1994; 40: 86-8
8. Balasubramaniam B, Park GR. Sexual hallucinations during and after sedation and anaesthesia. Anaesthesia 2003; 58: 549-53
9. Hall RC, Zisook S. Paradoxical reactions to benzodiazepines. Br J Clin Pharmacol 1981; 11 (Suppl 1): 99-104S
10. Weinbroum AA, Szold O, Ogorek D, Flaishon R. The midazolam-induced paradox phenomenon is reversible by flumazenil. Epidemiology, patient characteristics and review of the literature. Eur J Anaesthesiol 2001; 18: 789-97
11. Short TG, Forrest P, Galletly DC. Paradoxical reactions to benzodiazepines- a genetically determined phenomenon? Anaesth Intensive Care 1987; 15: 330-1
12. Wilcox CM, Forsmark CE, Cello JP. Utility of droperidol for conscious sedation in gastrointestinal endoscopic procedures. Gastrointest Endosc 1990; 36: 112-5
13. Hara M, Kai Y, Ikemoto Y. Propofol activates GABAA receptorchloride ionophore complex in dissociated hippocampal pyramidal neurons of the rat. Anesthesiology 1993; 79: 781-8
14. Davies M. The role of GABAA receptors in mediating the effects of alcohol in the central nervous system. J Psychiatry Neurosci 2003; 28: 263-74
15. Coulton S, Drummond C, James D, et al. Opportunistic screening for alcohol use disorders in primary care: comparative study. Br Med J 2006; 332: 511-7
16. Allen J, Reinert D, Volk R. The alcohol use disorders identification test: an aid to recognition of alcohol problems in primary care patients. Prev Med 2001; 33: 428-33
17. Parworth LP, Frost DE, Zuniga JR, Bennett T. Propofol and fentanyl compared with midazolam and fentanyl during third molar surgery. J Oral Maxillofac Surg 1998; 56: 447-53
18. McCarthy MM, Brown EN, Kopell N. Potential network mechanisms mediating electroencephalographic beta rhythm changes during propofol-induced paradoxical excitation. J Neurosci 2008; 28: 13488-504
19. Senel FC, Buchanan JM Jr, Senel AC, Obeid G. Evaluation of sedation failure in the outpatient oral and maxillofacial surgery clinic. J Oral Maxillofac Surg 2007; 65: 645-50
20. Fanard L, Van Steenberge A, Demeire X, van der Puyl F. Comparison between propofol and midazolam as sedative agents for surgery under regional anaesthesia. Anaesthesia 1988; 43 (Suppl): 87-9
21. McKenzie WS, Rosenberg M. Paradoxical reaction following administration of a benzodiazepine. J Oral Maxillofac Surg 2010; 68: 3034-6