Cytotoxic not vasogenic edema is the cause for stroke-like episodes in propionic acidemia

Neuropediatrics

Volumn 42, Issue 5, 2011, Pages 210-

  Karall, D ^a   Haberlandt, E ^a   Schimmel, M ^a   Schocke, M ^a   Gautsch, K ^a   Albrecht, U ^a   Baumgartner Sigl, S ^a   Scholl Brgi, S ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

WATER;

BEHAVIOR CHANGE; BRAIN EDEMA; CASE REPORT; CAUDATE NUCLEUS; CEREBELLUM; CHILD; CHILD BEHAVIOR; CONFUSION; CYTOTOXIC EDEMA; CYTOTOXICITY; DIFFUSION; ELECTROENCEPHALOGRAM; GASTROINTESTINAL INFECTION; GLIOSIS; HUMAN; LETTER; MALE; NEUROIMAGING; NEUROTOXICITY; NEWBORN SCREENING; NUCLEAR MAGNETIC RESONANCE IMAGING; OCCIPITAL LOBE; PRESCHOOL CHILD; PRIORITY JOURNAL; PROPIONIC ACIDEMIA; PUTAMEN; STROKE; TEMPORAL LOBE;

BASAL GANGLIA; FEMALE; HUMANS; PROPIONIC ACIDEMIA;

EID: 81855205041     PISSN: 0174304X     EISSN: 14391899     Source Type: Journal    
DOI: 10.1055/s-0031-1287772     Document Type: Letter

References (4)

1. Scholl-Brgi S, Haberlandt E, Gotwald T et al. Stroke-like episodes in propionic acidemia caused by central focal metabolic decompensation. Neuropediatrics: 2009; 40 76 81
2. Broomfield A, Gunny R, Prabhakar P et al. Spontaneous rapid resolution of acute basal ganglia changes in an untreated infant with propionic academia: A clue to pathogenesis? Neuropediatrics: 2010; 41 256 260
3. Sauer S W, Opp S, Mahringer A et al. Glutaric aciduria type I and methylmalonic aciduria: simulation of cerebral import and export of accumulating neurotoxic dicarboxylic acids in in vitro models of the blood-brain barrier and the choroid plexus. Biochim Biophys Acta: 2010; 1802 552 560
4. Brunengraber H, Roe C R. Anaplerotic molecules: current and future. J Inher Metab Dis: 2006; 29 327 331 (Pubitemid 43880628)