Noradrenaline contracts rat retinal arterioles via stimulation of α 1A- and α 1D-adrenoceptors

European Journal of Pharmacology

Volumn 673, Issue 1-3, 2011, Pages 65-69

  Mori, Asami ^a   Hanada, Masayuki ^a   Sakamoto, Kenji ^a   Nakahara, Tsutomu ^a   Ishii, Kunio ^a  

^a KITASATO UNIVERSITY   (Japan)

Author keywords

1 Adrenoceptor; Retinal circulation; Vasoconstriction

Indexed keywords

8 [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] 8 AZASPIRO[4.5]DECANE 7,9 DIONE; ALPHA 1A ADRENERGIC RECEPTOR; ALPHA 1D ADRENERGIC RECEPTOR; ALPHA ADRENERGIC RECEPTOR BLOCKING AGENT; N [5 (4,5 DIHYDRO 1H IMIDAZOL 2 YL) 5,6,7,8 TETRAHYDRO 2 HYDROXY 1 NAPHTHYL]METHANESULFONAMIDE; NORADRENALIN; PROPRANOLOL;

ADRENERGIC STIMULATION; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTERY CONSTRICTION; ARTICLE; BLOOD PRESSURE MONITORING; CONTROLLED STUDY; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG EFFECT; DRUG MECHANISM; EYE FUNDUS; HEART RATE; IN VITRO STUDY; MALE; NONHUMAN; PERIPHERAL CIRCULATION; PRIORITY JOURNAL; PROTEIN FUNCTION; RAT; RETINA ARTERY; RETINA BLOOD VESSEL; SYSTEMIC CIRCULATION; VASCULAR RESISTANCE;

ADRENERGIC ALPHA-1 RECEPTOR AGONISTS; ADRENERGIC ALPHA-1 RECEPTOR ANTAGONISTS; ANIMALS; BLOOD PRESSURE; DOSE-RESPONSE RELATIONSHIP, DRUG; HEART RATE; MALE; NOREPINEPHRINE; PROPRANOLOL; RATS; RATS, WISTAR; RECEPTORS, ADRENERGIC, ALPHA-1; RETINAL ARTERY; VASOCONSTRICTION; VASOCONSTRICTOR AGENTS;

EID: 81855198993     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2011.10.012     Document Type: Article

References (33)

1. S. Benedito, D. Prieto, P.J. Nielsen, and N.C. Nyborg Role of the endothelium in acetylcholine-induced relaxation and spontaneous tone of bovine isolated retinal small arteries Exp. Eye Res. 52 1991 575 579
2. K. Boussery, C. Delaey, and J. Van de Voorde Rat retinal tissue releases a vasorelaxing factor Invest. Ophthalmol. Vis. Sci. 43 2002 3279 3286
3. 1D-adrenoceptors contribute to the neurogenic vasopressor response in pithed rats Fundam. Clin. Pharmacol. 12 1998 584 589 (Pubitemid 29535480)
4. Y. Chaput, and C. de Montigny Effects of the 5-hydroxytryptamine receptor antagonist, BMY 7378, on 5-hydroxytryptamine neurotransmission: electrophysiological studies in the rat central nervous system J. Pharmacol. Exp. Ther. 246 1988 359 370
5. 1A receptors in the control of the micturition reflex in male anaesthetized rats Br. J. Pharmacol. 133 2001 61 72 (Pubitemid 32500452)
6. C. Delaey, and J. Van de Voorde Retinal arterial tone is controlled by a retinal-derived relaxing factor Circ. Res. 83 1998 714 720 (Pubitemid 28462785)
7. C. Delaey, and J. Van De Voorde Regulatory mechanisms in the retinal and choroidal circulation Ophthalmic Res. 32 2000 249 256
8. J.P. De La Cruz, J.A. Gonzalez-Correa, A. Guerrero, and F.S. de la Cuesta Pharmacological approach to diabetic retinopathy Diabetes Metab. Res. Rev. 20 2004 91 113
9. 1-adrenoceptor Cell. Mol. Life Sci. 67 2010 405 417
10. J. Flammer, S. Orgul, V.P. Costa, N. Orzalesi, G.K. Krieglstein, L.M. Serra, J.P. Renard, and E. Stefansson The impact of ocular blood flow in glaucoma Prog. Retin. Eye Res. 21 2002 359 393 (Pubitemid 34879080)
11. 1- adrenoceptors Eur. J. Pharmacol. 272 1995 R5 R6
12. M.C. Grieshaber, and J. Flammer Blood flow in glaucoma Curr. Opin. Ophthalmol. 16 2005 79 83 (Pubitemid 43790798)
13. I.O. Haefliger, J. Flammer, and T.F. Luscher Nitric oxide and endothelin-1 are important regulators of human ophthalmic artery Invest. Ophthalmol. Vis. Sci. 33 1992 2340 2343
14. P. Hardy, D. Abran, X. Hou, I. Lahaie, K.G. Peri, P. Asselin, D.R. Varma, and S. Chemtob A major role for prostacyclin in nitric oxide-induced ocular vasorelaxation in the piglet Circ. Res. 83 1998 721 729 (Pubitemid 28462786)
15. M.B. Hussain, and I. Marshall Characterization of alpha1-adrenoceptor subtypes mediating contractions to phenylephrine in rat thoracic aorta, mesenteric artery and pulmonary artery Br. J. Pharmacol. 122 1997 849 858 (Pubitemid 27460166)
16. Y. Kaneko, M. Saito, A. Mori, K. Sakamoto, T. Nakahara, and K. Ishii Vasodilator effects of adrenomedullin on retinal arterioles in streptozotocin-induced diabetic rats J. Ocul. Pharmacol. Ther. 22 2006 317 322 (Pubitemid 44706523)
17. W.G. Lachnit, A.M. Tran, D.E. Clarke, and A.P. Ford Pharmacological characterization of an alpha 1A-adrenoceptor mediating contractile responses to noradrenaline in isolated caudal artery of rat Br. J. Pharmacol. 120 1997 819 826
18. A. Mori, O. Saigo, M. Hanada, T. Nakahara, and K. Ishii Hyperglycemia accelerates impairment of vasodilator responses to acetylcholine of retinal blood vessels in rats J. Pharmacol. Sci. 110 2009 160 168
19. 3-adrenoceptors in rat retinal blood vessels Naunyn-Schmiedeberg's Arch. Pharmacol. 382 2010 119 126
20. A. Mori, T. Nakahara, K. Sakamoto, and K. Ishii Role of β3-adrenoceptors in regulation of retinal vascular tone in rats Naunyn-Schmiedeberg's Arch Pharmacol. 384 2011 603 608
21. T. Nakane, G. Tsujimoto, K. Hashimoto, and S. Chiba β Adrenoceptors in the canine large coronary arteries: β1-adrenoceptors predominate in vasodilation J. Pharmacol. Exp. Ther. 245 1988 936 943
22. T. Nakazawa, Y. Kaneko, A. Mori, M. Saito, K. Sakamoto, T. Nakahara, and K. Ishii Attenuation of nitric oxide- and prostaglandin-independent vasodilation of retinal arterioles induced by acetylcholine in streptozotocin-treated rats Vasc. Pharmacol. 46 2007 153 159 (Pubitemid 46096809)
23. T. Nakazawa, A. Sato, A. Mori, M. Saito, K. Sakamoto, T. Nakahara, and K. Ishii β-Adrenoceptor-mediated vasodilation of retinal blood vessels is reduced in streptozotocin-induced diabetic rats Vasc. Pharmacol. 49 2008 77 83
24. N. Ogawa, A. Mori, M. Hasebe, M. Hoshino, M. Saito, K. Sakamoto, T. Nakahara, and K. Ishii Nitric oxide dilates rat retinal blood vessels by cyclooxygenase-dependent mechanisms Am. J. Physiol. Regul. Integr. Comp. Physiol. 297 2009 R968 R977
25. N. Ogawa, M. Saito, A. Mori, K. Sakamoto, S. Kametaka, T. Nakahara, and K. Ishii Vasodilator effect of nicorandil on retinal blood vessels in rats Naunyn- Schmiedeberg's Arch. Pharmacol. 375 2007 323 328 (Pubitemid 46945335)
26. 1b adrenergic receptor antagonist J. Med. Chem. 41 1998 1205 1208 (Pubitemid 28208175)
27. 1-Adrenergic receptors: new insights and directions J. Pharmacol. Exp. Ther. 298 2001 403 410 (Pubitemid 32673390)
28. L. Schmetterer, and M. Wolzt Ocular blood flow and associated functional deviations in diabetic retinopathy Diabetologia 42 1999 387 405 (Pubitemid 29148397)
29. E.N. Su, D.Y. Yu, V.A. Alder, P.K. Yu, and S.J. Cringle Altered vasoactivity in the early diabetic eye: measured in the isolated perfused rat eye Exp. Eye Res. 61 1995 699 711 (Pubitemid 26017015)
30. 1-adrenergic peripheral vasodilation in conscious dogs Am. J. Physiol. 249 1985 H49 H56
31. 1A-adrenoceptor selective antagonists Br. J. Pharmacol. 127 1999 252 258 (Pubitemid 29213256)
32. 1-Adrenoceptor subtypes Eur. J. Pharmacol. 375 1999 261 276
33. 1D-adrenoceptors have a role in the pressor response to phenylephrine in the pithed rat Eur. J. Pharmacol. 305 1996 173 176