Comparing analgesic effects of a topical herbal mixed medicine with salicylate in patients with knee osteoarthritis

Pakistan Journal of Biological Sciences

Volumn 14, Issue 13, 2011, Pages 715-719

  Zahmatkash, Mohsen ^a   Vafaeenasab, Mohammad Reza ^b  

^a Farateb Research Institute   (Iran)

^b Shahid Sedoghi University of Medical Sciences   (Iran)

Author keywords

Herbal medicine; Osteoarthritis; Randomized controlled trial

Indexed keywords

ANALGESIC AGENT; NONSTEROID ANTIINFLAMMATORY AGENT; SALICYLIC ACID DERIVATIVE;

ADULT; ARTICLE; CHEMISTRY; CLINICAL TRIAL; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG COMBINATION; FEMALE; HERBAL MEDICINE; HUMAN; KNEE OSTEOARTHRITIS; MALE; MIDDLE AGED; OINTMENT; RANDOMIZED CONTROLLED TRIAL; TOPICAL DRUG ADMINISTRATION;

ADMINISTRATION, TOPICAL; ADULT; ANALGESICS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; DOUBLE-BLIND METHOD; DRUG COMBINATIONS; FEMALE; HERBAL MEDICINE; HUMANS; MALE; MIDDLE AGED; OINTMENTS; OSTEOARTHRITIS, KNEE; SALICYLATES;

CINNAMOMUM VERUM; SESAMUM INDICUM; ZINGIBER OFFICINALE;

EID: 81855172327     PISSN: 10288880     EISSN: 18125735     Source Type: Journal    
DOI: 10.3923/pjbs.2011.715.719     Document Type: Article

References (32)

1. Altman, R.D. and K.C. Marcussen, 2001. Effects of a ginger extract on knee pain in patients with osteoarthritis. Arthritis Rheumatism, 44: 2531-2538.
2. Altman, R.D., 2009. Practical considerations for the pharmacologic management of osteoarthritis. Am. J. Manage. Care, 15: S236-S243.
3. Ameye, L.G. and W.S. Chee, 2006. Osteoarthritis and nutrition. From nutraceuticals to functional foods: A systematic review of the scientific evidence. Arthritis Res. Ther., 8: R127-R127.
4. Bliddal, H., A. Rosetzsky, P. Schlichting, M.S. Weidner and L.A. Andersen et al., 2000. A randomized, placebo controlled, cross-over study of ginger extracts and Ibuprofen in osteoarthritis. Osteoarthritis Cartilage, 8: 9-12.
5. Buffum, M. and J.C. Buffum, 2000. Nonsteroidal anti-inflammatory drugs in the elderly. Pain Manage. Nurs., 1: 40-50.
6. Chao, L.K., K.F. Hua, H.Y. Hsu, S. S. Cheng, J.Y. Liu and S.T. Chang, 2005. Study on the antiinflammatoiy activity of essential oil from leaves of Cinnamomum osmophloeum. J. Agric. Food Chem., 53: 7274-7278.
7. Creamer, P. and M.C. Hochberg, 1997. Osteoarthritis. Lancet, 350: 503-509.
8. Creamer, P., R. Flores and M.C. Hochberg, 1998. Management of osteoarthritis in older adults. Clin. Geriatr. Med., 14: 435-454.
9. Cross, S.E., C. Anderson and M.S. Roberts, 1998. Topical penetration of commercial salicylate esters and salts using human isolated skin and clinical microdialysis studies. Br. J. Clin. Pharmacol., 46: 29-35.
10. Felson, D.T., 1993. The course of osteoarthritis and factors that affect it. Rheum Dis. Clin. North Am., 19: 607-615.
11. Gemmell, H.A., B.H. Jacobson and B.M. Hayes, 2003. Effect of a topical herbal cream on osteoarthritis of the hand and knee: A pilot study. J. Manipulative Physiol. Ther., 26: 322-322.
12. Gregory, P.J., M. Sperry and A.F. Wilson, 2008. Dietary supplements for osteoarthritis. Am. Fam Physician, 77: 177-184.
13. Grzanna, R., L. Lindmark and C.G. Frondoza, 2005. Ginger-an herbal medicinal product with broad anti-inflammatoiy actions. J. Med. Food., 8: 125-132.
14. Gulcin, I., M.E. Buyukokuroglu, M. Oktay and O.I. Kufrevioglu, 2003. Antioxidant and analgesic activities of turpentine of Pinus nigra Am. subsp. pallsiana (Lamb.) Holmboe. J. Ethnopharmacol., 86: 51-58.
15. Haghighi, M., A. Khalvat, T. Toliat and S. Jallaei, 2005. Comparing the effects of ginger (Zingiber officinale) extract and ibuprofen on patients with osteoarthritis. Arch. Iran. Med., 8: 267-271.
16. Haghighi, M., A. Khalvat, T. Touliat, H.F. Hoseini, S. Jalaei, M.R. Eshraghian and A. Ebrahimi, 2003. The effect of ginger extract on reduction of pain in patients with osteoarthritis: A randomized, duble blind, placebo-controlled trial. Physiol. Pharmacol. J., 7: 65-72.
17. Hochberg, M.C., R.D. Altman, K.D. Brandt, B.M. Clark and P.A. Dieppe et al., 1995. Guidelines for the medical management of osteoarthritis. Arthritis Rheum, 38: 1541-1546.
18. Hungin, A.P.S. and W.F. Kean, 2001. Nonsteroidal anti-inflammatory drugs: Overused or underused in osteoarthritis? Am. J. Med., 110: S8-S11.
19. Joshi, K., S. Awte, P. Bhatnagar, S. Walunj and R. Gupta et al., 2010. Cinnamomum zeylanicum extract inhibits pro inflammatory cytokine Inf ì: In vitro and in vivo studies. Res. Pharm. Biotechnol., 2: 14-21.
20. Kremer, J.M., D.A. Lawrence, W. Jubiz, R. Digiacomo, R. Rynes, L.E. Bartholomew and M. Sherman, 1990. Dietary fish oil and olive oil supplementation in patients with rheumatoid arthritis. Arthritis Rheum, 33: 810-810.
21. Lin, J., W. Zhang, A. Jones and M. Doherty, 2004. Efficacy of topical non-steroidal anti-inflammatory drugs in the treatment of osteoarthritis: Meta-analysis of randomised controlled trials. Biomed. J., 329: 324-324.
22. Linos, A., V.G. Kaklamani, E. Kaklamani, Y. Koumantaki, E. Giziaki, S. Papazoglou and C.S. Mantzoros, 1999. Dietary factors in relation to rheumatoid arthritis: A role for olive oil and cooked vegetables? Am. J. Clin. Nutr., 70: 1077-1082.
23. Martel-Pelletier, J., C. Boileau, J.P. Pelletier and J.P. Pelletier, 2008. Cartilage in normal and osteoarthritis conditions. Best Pract. Res. Clin. Rheumatol., 22: 351-384.
24. Miller, M. J., K. Mehta, S. Kunte, V. Raut and J. Gala et al., 2005. Early relief of osteoarthritis symptoms with a natural mineral supplement and a herbomineral combination: A randomized controlled trial [ISRCTN38432711]. J. Inflamm., 2: 11-11.
25. Montes-Belmont, R. and M. Carvajal, 1998. Control of Aspergillus flavus in maize with plant essential oils and their components. J. Food Prot., 61: 616-619.
26. Petrella, R.J., M.D. DiSilvestro and C. Hildebrand, 2002. Effects of hyaluronate sodium on pain and physical functioning in osteoarthritis of the knee: A randomized, double-blind, placebo-controlled clinical trial. Arch. Internal Med., 162: 292-298.
27. Roth, S.H. and J.Z. Shainhouse, 2004. Efficacy and safety of a topical diclofenac solution (pennsaid) in the treatment of primary osteoarthritis of the knee: A randomized, double-blind, vehicle-controlled clinical trial. Arch. Internal Med., 164: 2017-2023.
28. Shackel, N.A., R.O. Day, B. Kellett and P.M. Brooks, 1997. Copper-salicylate gel for pain relief in osteoarthritis: A randomised controlled trial. Med. J. Aust., 167: 134-136.
29. Shen, C.L., K.J. Hong and S.W. Kim, 2005. Comparative effects of ginger root (zingiber officinale rose.) on the production of inflammatory mediators in normal and osteoarthrotic sow chondrocytes. J. Med. Food, 8: 149-153.
30. Teekachunhatean, S., P. Kunanusorn, N. Rojanasthien, K. Sananpanich, S. Pojchamamwiputh, S. Lhieochaiphunt and S. Pruksakorn, 2004. Chinese herbal recipe versus diclofenac in symptomatic treatment of osteoarthritis of the knee: A randomized controlled trial [isrctn70292892], BMC Complement Altern. Med., 4: 19-19.
31. Van Haselen, R.A. and P.A. Fisher, 2000. A randomized controlled trial comparing topical piroxicam gel with a homeopathic gel in osteoarthritis of the knee. Rheumatology, 39: 714-719.
32. WHO, 1998. Regulatory situation of herbal medicines: A worldwide review. WHO/TRM/98.1, pp: 1-49. http://whqlibdoc.who.int/hq/1998/WHO_TRM_98. 1.pdf