Two-minute heart rate recovery after cycle ergometer exercise and all-cause mortality in middle-aged men

Journal of Internal Medicine

Volumn 270, Issue 6, 2011, Pages 589-596

  Savonen, K P ^a,b   Kiviniemi, V ^a   Laaksonen, D E ^a,b   Lakka, T A ^a   Laukkanen, J A ^a,c   Tuomainen, T P ^a   Rauramaa, R ^a,b  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

^b KUOPIO UNIVERSITY HOSPITAL   (Finland)

^c LAPLAND CENTRAL HOSPITAL   (Finland)

Author keywords

Mortality; Risk factors

Indexed keywords

ADULT; AGE; ARTICLE; BICYCLE ERGOMETRY; CHRONOTROPISM; EXERCISE TEST; HEART RATE; HUMAN; MAJOR CLINICAL STUDY; MALE; MORTALITY; PRIORITY JOURNAL; PROGNOSIS; RISK FACTOR;

ADULT; CARDIOVASCULAR DISEASES; CAUSE OF DEATH; COHORT STUDIES; EXERCISE; EXERCISE TEST; EXERCISE TOLERANCE; FINLAND; FOLLOW-UP STUDIES; HEART RATE; HUMANS; MALE; MIDDLE AGED; MORTALITY, PREMATURE; PREDICTIVE VALUE OF TESTS; PROPORTIONAL HAZARDS MODELS;

EID: 81855166818     PISSN: 09546820     EISSN: 13652796     Source Type: Journal    
DOI: 10.1111/j.1365-2796.2011.02434.x     Document Type: Article

References (19)

1. Cole CR, Foody JM, Blackstone EH, Lauer MS. Heart rate recovery after submaximal exercise testing as a predictor of mortality in a cardiovascularly healthy cohort. Ann Intern Med 2000; 132: 552-5.
2. Mora S, Redberg RF, Cui Y et al. Ability of exercise testing to predict cardiovascular and all-cause death in asymptomatic women: a 20-year follow-up of the lipid research clinics prevalence study. JAMA 2003; 290: 1600-7.
3. Aktas MK, Ozduran V, Pothier CE, Lang R, Lauer MS. Global risk scores and exercise testing for predicting all-cause mortality in a preventive medicine program. JAMA 2004; 292: 1462-8.
4. Adabag AS, Grandits GA, Prineas RJ et al. Relation of heart rate parameters during exercise test to sudden death and all-cause mortality in asymptomatic men. Am J Cardiol 2008; 101: 1437-43.
5. Wandell PE, Carlsson AC, Theobald H. Effect of heart-rate recovery on long-term mortality among men and women. Int J Cardiol 2010; 144: 276-9.
6. Morshedi-Meibodi A, Larson MG, Levy D, O'Donnell CJ, Vasan RS. Heart rate recovery after treadmill exercise testing and risk of cardiovascular disease events (The Framingham Heart Study). Am J Cardiol 2002; 90: 848-52.
7. Jouven X, Empana JP, Schwartz PJ, Desnos M, Courbon D, Ducimetiere P. Heart-rate profile during exercise as a predictor of sudden death. N Engl J Med 2005; 352: 1951-8.
8. Erikssen G, Bodegard J, Bjornholt JV, Liestol K, Thelle DS, Erikssen J. Exercise testing of healthy men in a new perspective: from diagnosis to prognosis. Eur Heart J 2004; 25: 978-86.
9. Salonen JT. Is there a continuing need for longitudinal epidemiologic research? The Kuopio Ischaemic Heart Disease Risk Factor Study. Ann Clin Res 1988; 20: 46-50.
10. Lakka TA, Venalainen JM, Rauramaa R, Salonen R, Tuomilehto J, Salonen JT. Relation of leisure-time physical activity and cardiorespiratory fitness to the risk of acute myocardial infarction. N Engl J Med 1994; 330: 1549-54.
11. Savonen KP, Lakka TA, Laukkanen JA et al. Heart rate response during exercise test and cardiovascular mortality in middle-aged men. Eur Heart J 2006; 27: 582-8.
12. Salonen JT, Salonen R, Seppanen K, Rauramaa R, Tuomilehto J. HDL, HDL2, and HDL3 subfractions, and the risk of acute myocardial infarction. A prospective population study in eastern Finnish men. Circulation 1991; 84: 129-39.
13. D'Agostino RB, Nam B. Evaluation of the performance of survival analysis models: discrimination and calibration measures. In: Balakrishnan N, Rao CR, eds. Handbook of Statistics, Advances in Survival Analysis, Vol 23. Boston: Elsevier, 2004; 1-26.
14. Harrell FE Jr, Lee KL, Mark DB. Multivariable prognostic models: issues in developing models, evaluating assumptions and adequacy, and measuring and reducing errors. Stat Med 1996; 15: 361-87.
15. Pencina MJ, D'Agostino RB Sr, D'Agostino RB Jr, Vasan RS. Evaluating the added predictive ability of a new marker: from area under the ROC curve to reclassification and beyond. Stat Med 2008; 27: 157-72.
16. Hlatky MA, Greenland P, Arnett DK et al. Criteria for evaluation of novel markers of cardiovascular risk: a scientific statement from the American Heart Association. Circulation 2009; 119: 2408-16.
17. Mora S, Redberg RF, Sharrett AR, Blumenthal RS. Enhanced risk assessment in asymptomatic individuals with exercise testing and Framingham risk scores. Circulation 2005; 112: 1566-72.
18. Desai MY, Dela Pena-Almaguer E, Mannting F. Abnormal heart rate recovery after exercise as a reflection of an abnormal chronotropic response. Am J Cardiol 2001; 87: 1164-9.
19. Gorodeski EZ, Ishwaran H, Blackstone EH, Lauer MS. Quantitative electrocardiographic measures and long-term mortality in exercise test patients with clinically normal resting electrocardiograms. Am Heart J 2009; 158: 61-70.