Prevalence and demographic features of early-onset neurodegenerative dementia in Brescia County, Italy

Alzheimer Disease and Associated Disorders

Volumn 25, Issue 4, 2011, Pages 341-344

  Borroni, Barbara ^a   Alberici, Antonella ^a   Grassi, Mario ^b   Rozzini, Luca ^a   Turla, Marinella ^c   Zanetti, Orazio ^d   Bianchetti, Angelo ^e   Gilberti, Nicola ^a   Bonvicini, Cristian ^d   Volta, Giorgio Dalla ^f   Rozzini, Renzo ^g   Padovani, Alessandro ^a  

^a UNIVERSITY OF BRESCIA   (Italy)

^b UNIVERSITY OF PAVIA   (Italy)

^c Vallecamonica Hospital   (Italy)

^d IRCCS Fatebenefratelli   (Italy)

^e S ANNA HOSPITAL   (Italy)

^f Neurology Unit   (Italy)

^g Poliambulanza Hospital   (Italy)

Author keywords

Alzheimer disease; Early onset dementia; epidemiology; frontotemporal dementia; frontotemporal lobar degeneration; presenile; prevalence

Indexed keywords

ADULT; AGE DISTRIBUTION; AGED; ALZHEIMER DISEASE; ARTICLE; CONTROLLED STUDY; DEMOGRAPHY; FEMALE; FRONTOTEMPORAL DEMENTIA; HUMAN; ITALY; MAJOR CLINICAL STUDY; MALE; ONSET AGE; POPULATION RESEARCH; PRIORITY JOURNAL; SEX RATIO;

AGED; ALZHEIMER DISEASE; FEMALE; FRONTOTEMPORAL LOBAR DEGENERATION; HUMANS; ITALY; MALE; MIDDLE AGED; PREVALENCE;

EID: 81855166620     PISSN: 08930341     EISSN: None     Source Type: Journal    
DOI: 10.1097/WAD.0b013e3182147f80     Document Type: Article

References (21)

1. Mc Khann G, Drachman D, Folstein M, et al. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology. 1984;34:939-944. (Pubitemid 14076461)
2. Neary D, Snowden JS, Gustafson L, et al. Frontotemporal lobar degeneration: a consensus on clinical diagnostic criteria. Neurology. 1998;51:1546-1554.
3. Mc Khann GM, Albert MS, Grossman M, et al. Clinical and pathological diagnosis of frontotemporal dementia: report of the Work Group on Frontotemporal Dementia and Pick's Disease. Arch Neurol. 2001;58:1803-1809. (Pubitemid 33044246)
4. Bertram L, Tanzi RE. Thirty years of Alzheimer's disease genetics: the implications ofsystematic meta-analyses. Nat Rev Neurosci. 2008;9:768-778.
5. Rademakers R, Rovelet-Lecrux A. Recent insights into the molecular genetics of dementia. Trends Neurosci. 2009;32:451-461.
6. Borroni B, Bonvicini C, Alberici A, et al. Mutation within TARDBP leads to frontotemporal dementia without motor neuron disease. Hum Mutat. 2009;30:974-983.
7. Harvey RJ, Skelton-Robinson M, Rossor MN. The prevalence and causes of dementia in people under the age of 65 years. J Neurol Neurosurg Psychiatry. 2003;74:1206-1209.
8. Mercy L, Hodges JR, Dawson K, et al. Incidence of early-onset dementias in Cambridgeshire, United Kingdom. Neuro-logy. 2008;71:1496-1499.
9. Ratnavalli E, Brayne C, Dawson K, et al. The prevalence of frontotemporal dementia. Neurology. 2002;58:1615-1621. (Pubitemid 34602891)
10. Rosso SM, Donker Kaat L, Baks T, et al. Frontotemporal dementia in The Netherlands: patient characteristics and prevalence estimates from a population-based study. Brain. 2003;126:2016-2022. (Pubitemid 37059441)
11. Garre-Olmo J, Genis batlle D, del Mar Fernandez M, et al. Incidence and subtypes of early-onset dementia in a geographi-cally defined general population. Neurology. 2010;75:1249-1255.
12. Alberici A, Bonato C, Borroni B, et al. Dementia, delusions and seizures: storage disease or genetic AD? Eur J Neurol. 2007;14:1057-1059. (Pubitemid 47300760)
13. Bugiani O, Padovani A, Magoni M. An Italian type of HCHWA. Neurobiology Aging. 1998;19:S238. Abs.
14. Alberici A, Gobbo C, Panzacchi A, et al. Frontotemporal dementia: impact of P301L tau mutation on a healthy carrier. J Neurol Neurosurg Psychiatry. 2004;75:1607-1610. (Pubitemid 39430616)
15. Borroni B, Archetti S, Alberici A, et al. Progranulin genetic variations in frontotemporal lobar degeneration: evidence for low mutation frequency in an Italian clinical series. Neuroge-netics. 2008;9:197-205.
16. Andreasen N, Blennow K, Sjodin C, et al. Prevalence and incidence of clinically diagnosed memory impairments in a geographically defined general population in Sweden: the Pitea dementia project. Neuroepidemiology. 1999;18:!144-155. (Pubitemid 29185849)
17. Campion D, Dumanchin C, Hannequin D, et al. Early-onset autosomal dominant Alzheimer disease: prevalence, genetic heterogeneity, and mutation spectrum. Am J Hum Genet. 1999;65:664-670. (Pubitemid 30468710)
18. Kokmen E, Beard CM, Offord KP, et al. Prevalence of medically diagnosed dementia in a defined United States population: Rochester, Minnesota, January 1, 1975. Neuro-logy. 1989;39:773-776. (Pubitemid 19150149)
19. Borroni B, Alberici A, Grassi M, et al. Is frontotemporal lobar degeneration a rare disorder? Evidence from a preliminary study in Brescia County, Italy. J Alzheimers Dis. 2010;19: 111-116.
20. Kaiser S, Panegyres PK. The psychosocial impact of young onset dementia on spose. Am J Alzheimer Dis Other Demen. 2007;21:398-402.
21. Boxer AL, Boeve BF. Frontotemporal dementia treatment: current symptomatic terapie and implications of recent genetic, biochemical, and neuroimaging studies. Alzheimer Dis Assoc Disord. 2007;21:S79-S87. (Pubitemid 350307449)