-
2
-
-
0034926291
-
The vanilloid receptor: A molecular gateway to the pain pathway
-
DOI 10.1146/annurev.neuro.24.1.487
-
Caterina MJ, Julius D (2001) The vanilloid receptor: A molecular gateway to the pain pathway. Annu Rev Neurosci 24:487-517. (Pubitemid 32695237)
-
(2001)
Annual Review of Neuroscience
, vol.24
, pp. 487-517
-
-
Caterina, M.J.1
Julius, D.2
-
3
-
-
0041878279
-
Lessons from peppers and peppermint: The molecular logic of thermosensation
-
DOI 10.1016/S0959-4388(03)00101-6
-
Jordt SE, McKemy DD, Julius D (2003) Lessons from peppers and peppermint: The molecular logic of thermosensation. Curr Opin Neurobiol 13:487-492. (Pubitemid 37088240)
-
(2003)
Current Opinion in Neurobiology
, vol.13
, Issue.4
, pp. 487-492
-
-
Jordt, S.-E.1
McKemy, D.D.2
Julius, D.3
-
4
-
-
18344386202
-
A TRP channel that senses cold stimuli and menthol
-
DOI 10.1016/S0092-8674(02)00652-9
-
Peier AM, et al. (2002) A TRP channel that senses cold stimuli and menthol. Cell 108:705-715. (Pubitemid 34241429)
-
(2002)
Cell
, vol.108
, Issue.5
, pp. 705-715
-
-
Peier, A.M.1
Moqrich, A.2
Hergarden, A.C.3
Reeve, A.J.4
Andersson, D.A.5
Story, G.M.6
Earley, T.J.7
Dragoni, I.8
McIntyre, P.9
Bevan, S.10
Patapoutian, A.11
-
6
-
-
1842475312
-
Noxious cold ion channel TRPA1 is activated by pungent compounds and bradykinin
-
DOI 10.1016/S0896-6273(04)00150-3, PII S0896627304001503
-
Bandell M, et al. (2004) Noxious cold ion channel TRPA1 is activated by pungent compounds and bradykinin. Neuron 41:849-857. (Pubitemid 38429729)
-
(2004)
Neuron
, vol.41
, Issue.6
, pp. 849-857
-
-
Bandell, M.1
Story, G.M.2
Hwang, S.W.3
Viswanath, V.4
Eid, S.R.5
Petrus, M.J.6
Earley, T.J.7
Patapoutian, A.8
-
7
-
-
33646045075
-
TRPA1 mediates the inflammatory actions of environmental irritants and proalgesic agents
-
Bautista DM, et al. (2006) TRPA1 mediates the inflammatory actions of environmental irritants and proalgesic agents. Cell 124:1269-1282.
-
(2006)
Cell
, vol.124
, pp. 1269-1282
-
-
Bautista, D.M.1
-
8
-
-
1642430679
-
Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1
-
Jordt SE, et al. (2004) Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1. Nature 427:260-265.
-
(2004)
Nature
, vol.427
, pp. 260-265
-
-
Jordt, S.E.1
-
9
-
-
34548094044
-
4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1
-
DOI 10.1073/pnas.0705923104
-
Trevisani M, et al. (2007) 4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1. Proc Natl Acad Sci USA 104:13519-13524. (Pubitemid 47293977)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.33
, pp. 13519-13524
-
-
Trevisani, M.1
Siemens, J.2
Materazzi, S.3
Bautista, D.M.4
Nassini, R.5
Campi, B.6
Imamachi, N.7
Andre, E.8
Patacchini, R.9
Cottrell, G.S.10
Gatti, R.11
Basbaum, A.I.12
Bunnett, N.W.13
Julius, D.14
Geppetti, P.15
-
10
-
-
77951114632
-
Molecular basis of infrared detection by snakes
-
Gracheva EO, et al. (2010) Molecular basis of infrared detection by snakes. Nature 464:1006-1011.
-
(2010)
Nature
, vol.464
, pp. 1006-1011
-
-
Gracheva, E.O.1
-
11
-
-
47049101429
-
An internal thermal sensor controlling temperature preference in Drosophila
-
DOI 10.1038/nature07001, PII NATURE07001
-
Hamada FN, et al. (2008) An internal thermal sensor controlling temperature preference in Drosophila. Nature 454:217-220. (Pubitemid 351969888)
-
(2008)
Nature
, vol.454
, Issue.7201
, pp. 217-220
-
-
Hamada, F.N.1
Rosenzweig, M.2
Kang, K.3
Pulver, S.R.4
Ghezzi, A.5
Jegla, T.J.6
Garrity, P.A.7
-
12
-
-
77950232179
-
Analysis of Drosophila TRPA1 reveals an ancient origin for human chemical nociception
-
Kang K, et al. (2010) Analysis of Drosophila TRPA1 reveals an ancient origin for human chemical nociception. Nature 464:597-600.
-
(2010)
Nature
, vol.464
, pp. 597-600
-
-
Kang, K.1
-
13
-
-
77956835666
-
Honey bee thermal/chemical sensor, AmHsTRPA, reveals neofunctionalization and loss of transient receptor potential channel genes
-
Kohno K, Sokabe T, Tominaga M, Kadowaki T (2010) Honey bee thermal/chemical sensor, AmHsTRPA, reveals neofunctionalization and loss of transient receptor potential channel genes. J Neurosci 30:12219-12229.
-
(2010)
J Neurosci
, vol.30
, pp. 12219-12229
-
-
Kohno, K.1
Sokabe, T.2
Tominaga, M.3
Kadowaki, T.4
-
14
-
-
13844250536
-
The Drosophila ortholog of vertebrate TRPA1 regulates thermotaxis
-
DOI 10.1101/gad.1278205
-
Rosenzweig M, et al. (2005) The Drosophila ortholog of vertebrate TRPA1 regulates thermotaxis. Genes Dev 19:419-424. (Pubitemid 40256272)
-
(2005)
Genes and Development
, vol.19
, Issue.4
, pp. 419-424
-
-
Rosenzweig, M.1
Brennan, K.M.2
Tayler, T.D.3
Phelps, P.O.4
Patapoutian, A.5
Garrity, P.A.6
-
15
-
-
77449112680
-
Structure-functional intimacies of transient receptor potential channels
-
Latorre R, Zaelzer C, Brauchi S (2009) Structure-functional intimacies of transient receptor potential channels. Q Rev Biophys 42:201-246.
-
(2009)
Q Rev Biophys
, vol.42
, pp. 201-246
-
-
Latorre, R.1
Zaelzer, C.2
Brauchi, S.3
-
16
-
-
79953156425
-
Irritating channels: The case of TRPA1
-
Nilius B, Prenen J, Owsianik G (2011) Irritating channels: the case of TRPA1. J Physiol 589:1543-1549.
-
(2011)
J Physiol
, vol.589
, pp. 1543-1549
-
-
Nilius, B.1
Prenen, J.2
Owsianik, G.3
-
17
-
-
34250190946
-
The Ankyrin Repeats of TRPV1 Bind Multiple Ligands and Modulate Channel Sensitivity
-
DOI 10.1016/j.neuron.2007.05.027, PII S0896627307004060
-
Lishko PV, Procko E, Jin X, Phelps CB, Gaudet R (2007) The ankyrin repeats of TRPV1 bind multiple ligands and modulate channel sensitivity. Neuron 54:905-918. (Pubitemid 46907502)
-
(2007)
Neuron
, vol.54
, Issue.6
, pp. 905-918
-
-
Lishko, P.V.1
Procko, E.2
Jin, X.3
Phelps, C.B.4
Gaudet, R.5
-
18
-
-
17044401714
-
In search of the hair-cell gating spring elastic properties of ankyrin and cadherin repeats
-
Sotomayor M, Corey DP, Schulten K (2005) In search of the hair-cell gating spring elastic properties of ankyrin and cadherin repeats. Structure 13:669-682.
-
(2005)
Structure
, vol.13
, pp. 669-682
-
-
Sotomayor, M.1
Corey, D.P.2
Schulten, K.3
-
19
-
-
42349109026
-
A primer on ankyrin repeat function in TRP channels and beyond
-
Gaudet R (2008) A primer on ankyrin repeat function in TRP channels and beyond. Mol Biosyst 4:372-379.
-
(2008)
Mol Biosyst
, vol.4
, pp. 372-379
-
-
Gaudet, R.1
-
20
-
-
0030777012
-
The capsaicin receptor: A heat-activated ion channel in the pain pathway
-
DOI 10.1038/39807
-
Caterina MJ, et al. (1997) The capsaicin receptor: A heat-activated ion channel in the pain pathway. Nature 389:816-824. (Pubitemid 27462969)
-
(1997)
Nature
, vol.389
, Issue.6653
, pp. 816-824
-
-
Caterina, M.J.1
Schumacher, M.A.2
Tominaga, M.3
Rosen, T.A.4
Levine, J.D.5
Julius, D.6
-
21
-
-
73649104785
-
Differential regulation of TRPV1, TRPV3, and TRPV4 sensitivity through a conserved binding site on the ankyrin repeat domain
-
Phelps CB, Wang RR, Choo SS, Gaudet R (2010) Differential regulation of TRPV1, TRPV3, and TRPV4 sensitivity through a conserved binding site on the ankyrin repeat domain. J Biol Chem 285:731-740.
-
(2010)
J Biol Chem
, vol.285
, pp. 731-740
-
-
Phelps, C.B.1
Wang, R.R.2
Choo, S.S.3
Gaudet, R.4
-
22
-
-
34250379970
-
Transient receptor potential channel A1 is directly gated by calcium ions
-
DOI 10.1074/jbc.M607849200
-
Doerner JF, Gisselmann G, Hatt H, Wetzel CH (2007) Transient receptor potential channel A1 is directly gated by calcium ions. J Biol Chem 282:13180-13189. (Pubitemid 47100541)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.18
, pp. 13180-13189
-
-
Doerner, J.F.1
Gisselmann, G.2
Hatt, H.3
Wetzel, C.H.4
-
23
-
-
33847241778
-
Direct activation of the ion channel TRPA1 by Ca2+
-
Zurborg S, Yurgionas B, Jira JA, Caspani O, Heppenstall PA (2007) Direct activation of the ion channel TRPA1 by Ca2+. Nat Neurosci 10:277-279.
-
(2007)
Nat Neurosci
, vol.10
, pp. 277-279
-
-
Zurborg, S.1
Yurgionas, B.2
Jira, J.A.3
Caspani, O.4
Heppenstall, P.A.5
-
24
-
-
57749107691
-
The nociceptor ion channel TRPA1 is potentiated and inactivated by permeating calcium ions
-
Wang YY, Chang RB, Waters HN, McKemy DD, Liman ER (2008) The nociceptor ion channel TRPA1 is potentiated and inactivated by permeating calcium ions. J Biol Chem 283:32691-32703.
-
(2008)
J Biol Chem
, vol.283
, pp. 32691-32703
-
-
Wang, Y.Y.1
Chang, R.B.2
Waters, H.N.3
McKemy, D.D.4
Liman, E.R.5
-
25
-
-
33845900989
-
TRP channel activation by reversible covalent modification
-
DOI 10.1073/pnas.0609598103
-
Hinman A, Chuang HH, Bautista DM, Julius D (2006) TRP channel activation by reversible covalent modification. Proc Natl Acad Sci USA 103:19564-19568. (Pubitemid 46026070)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.51
, pp. 19564-19568
-
-
Hinman, A.1
Chuang, H.-H.2
Bautista, D.M.3
Julius, D.4
-
26
-
-
33846692923
-
Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines
-
DOI 10.1038/nature05544, PII NATURE05544
-
Macpherson LJ, et al. (2007) Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines. Nature 445:541-545. (Pubitemid 46197634)
-
(2007)
Nature
, vol.445
, Issue.7127
, pp. 541-545
-
-
Macpherson, L.J.1
Dubin, A.E.2
Evans, M.J.3
Marr, F.4
Schultz, P.G.5
Cravatt, B.F.6
Patapoutian, A.7
-
27
-
-
33646899582
-
A hot-sensing cold receptor: C-terminal domain determines thermosensation in transient receptor potential channels
-
DOI 10.1523/JNEUROSCI.5080-05.2006
-
Brauchi S, Orta G, Salazar M, Rosenmann E, Latorre R (2006) A hot-sensing cold receptor: C-terminal domain determines thermosensation in transient receptor potential channels. J Neurosci 26:4835-4840. (Pubitemid 44315324)
-
(2006)
Journal of Neuroscience
, vol.26
, Issue.18
, pp. 4835-4840
-
-
Brauchi, S.1
Orta, G.2
Salazar, M.3
Rosenmann, E.4
Latorre, R.5
-
28
-
-
34547953765
-
ThermoTRP channels as modular proteins with allosteric gating
-
DOI 10.1016/j.ceca.2007.04.004, PII S0143416007000772
-
Latorre R, Brauchi S, Orta G, Zaelzer C, Vargas G (2007) ThermoTRP channels as modular proteins with allosteric gating. Cell Calcium 42:427-438. (Pubitemid 47264003)
-
(2007)
Cell Calcium
, vol.42
, Issue.4-5
, pp. 427-438
-
-
Latorre, R.1
Brauchi, S.2
Orta, G.3
Zaelzer, C.4
Vargas, G.5
-
29
-
-
0037799198
-
2 binding site as a determinant of capsaicin receptor sensitivity
-
DOI 10.1126/science.1083646
-
Prescott ED, Julius D (2003) A modular PIP2 binding site as a determinant of capsaicin receptor sensitivity. Science 300:1284-1288. (Pubitemid 36618238)
-
(2003)
Science
, vol.300
, Issue.5623
, pp. 1284-1288
-
-
Prescott, E.D.1
Julius, D.2
-
30
-
-
77952886805
-
Temperature-induced opening of TRPV1 ion channel is stabilized by the pore domain
-
Grandl J, et al. (2010) Temperature-induced opening of TRPV1 ion channel is stabilized by the pore domain. Nat Neurosci 13:708-714.
-
(2010)
Nat Neurosci
, vol.13
, pp. 708-714
-
-
Grandl, J.1
-
31
-
-
77951035804
-
Thermosensitive TRP channel pore turret is part of the temperature activation pathway
-
Yang F, Cui Y, Wang K, Zheng J (2010) Thermosensitive TRP channel pore turret is part of the temperature activation pathway. Proc Natl Acad Sci USA 107:7083-7088.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 7083-7088
-
-
Yang, F.1
Cui, Y.2
Wang, K.3
Zheng, J.4
-
32
-
-
79960580198
-
Modular thermal sensors in temperature-gated transient receptor potential (TRP) channels
-
Yao J, Liu B, Qin F (2011) Modular thermal sensors in temperature-gated transient receptor potential (TRP) channels. Proc Natl Acad Sci USA 108:11109-11114.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 11109-11114
-
-
Yao, J.1
Liu, B.2
Qin, F.3
-
33
-
-
77953271751
-
A bivalent tarantula toxin activates the capsaicin receptor, TRPV1, by targeting the outer pore domain
-
Bohlen CJ, et al. (2010) A bivalent tarantula toxin activates the capsaicin receptor, TRPV1, by targeting the outer pore domain. Cell 141:834-845.
-
(2010)
Cell
, vol.141
, pp. 834-845
-
-
Bohlen, C.J.1
-
34
-
-
0036183319
-
Molecular basis for species-specific sensitivity to "hot" chili peppers
-
Jordt SE, Julius D (2002) Molecular basis for species-specific sensitivity to "hot" chili peppers. Cell 108:421-430.
-
(2002)
Cell
, vol.108
, pp. 421-430
-
-
Jordt, S.E.1
Julius, D.2
-
35
-
-
0037034931
-
Identification of a cold receptor reveals a general role for TRP channels in thermosensation
-
DOI 10.1038/nature719
-
McKemy DD, Neuhausser WM, Julius D (2002) Identification of a cold receptor reveals a general role for TRP channels in thermosensation. Nature 416:52-58. (Pubitemid 34215395)
-
(2002)
Nature
, vol.416
, Issue.6876
, pp. 52-58
-
-
McKemy, D.D.1
Neuhausser, W.M.2
Julius, D.3
-
36
-
-
4544368241
-
The super-cooling agent icilin reveals a mechanism of coincidence detection by a temperature-sensitive TRP channel
-
DOI 10.1016/j.neuron.2004.08.038, PII S0896627304005380
-
Chuang HH, Neuhausser WM, Julius D (2004) The super-cooling agent icilin reveals a mechanism of coincidence detection by a temperature-sensitive TRP channel. Neuron 43:859-869. (Pubitemid 39215016)
-
(2004)
Neuron
, vol.43
, Issue.6
, pp. 859-869
-
-
Chuang, H.-H.1
Neuhausser, W.M.2
Julius, D.3
-
37
-
-
66849121992
-
Evolution of thermal response properties in a cold-activated TRP channel
-
Myers BR, Sigal YM, Julius D (2009) Evolution of thermal response properties in a cold-activated TRP channel. PLoS ONE 4:e5741.
-
(2009)
PLoS ONE
, vol.4
-
-
Myers, B.R.1
Sigal, Y.M.2
Julius, D.3
-
38
-
-
34548101399
-
TRPA1 mediates formalin-induced pain
-
DOI 10.1073/pnas.0705924104
-
McNamara CR, et al. (2007) TRPA1 mediates formalin-induced pain. Proc Natl Acad Sci USA 104:13525-13530. (Pubitemid 47293978)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.33
, pp. 13525-13530
-
-
McNamara, C.R.1
Mandel-Brehm, J.2
Bautista, D.M.3
Siemens, J.4
Deranian, K.L.5
Zhao, M.6
Hayward, N.J.7
Chong, J.A.8
Julius, D.9
Moran, M.M.10
Fanger, C.M.11
-
39
-
-
50249186498
-
Pore region of TRPV3 ion channel is specifically required for heat activation
-
Grandl J, et al. (2008) Pore region of TRPV3 ion channel is specifically required for heat activation. Nat Neurosci 11:1007-1013.
-
(2008)
Nat Neurosci
, vol.11
, pp. 1007-1013
-
-
Grandl, J.1
-
41
-
-
59049096524
-
TRPA1 acts as a cold sensor in vitro and in vivo
-
Karashima Y, et al. (2009) TRPA1 acts as a cold sensor in vitro and in vivo. Proc Natl Acad Sci USA 106:1273-1278.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 1273-1278
-
-
Karashima, Y.1
-
42
-
-
0345616438
-
ANKTM1, a TRP-like channel expressed in nociceptive neurons, is activated by cold temperatures
-
DOI 10.1016/S0092-8674(03)00158-2
-
Story GM, et al. (2003) ANKTM1, a TRP-like channel expressed in nociceptive neurons, is activated by cold temperatures. Cell 112:819-829. (Pubitemid 36378884)
-
(2003)
Cell
, vol.112
, Issue.6
, pp. 819-829
-
-
Story, G.M.1
Peier, A.M.2
Reeve, A.J.3
Eid, S.R.4
Mosbacher, J.5
Hricik, T.R.6
Earley, T.J.7
Hergarden, A.C.8
Andersson, D.A.9
Hwang, S.W.10
McIntyre, P.11
Jegla, T.12
Bevan, S.13
Patapoutian, A.14
-
43
-
-
78149485777
-
TRPA1 contributes to cold hypersensitivity
-
del Camino D, et al. (2010) TRPA1 contributes to cold hypersensitivity. J Neurosci 30:15165-15174.
-
(2010)
J Neurosci
, vol.30
, pp. 15165-15174
-
-
Del Camino, D.1
-
44
-
-
77955304238
-
TRPM8, but not TRPA1, is required for neural and behavioral responses to acute noxious cold temperatures and cold-mimetics in vivo
-
Knowlton WM, Bifolck-Fisher A, Bautista DM, McKemy DD (2010) TRPM8, but not TRPA1, is required for neural and behavioral responses to acute noxious cold temperatures and cold-mimetics in vivo. Pain 150:340-350.
-
(2010)
Pain
, vol.150
, pp. 340-350
-
-
Knowlton, W.M.1
Bifolck-Fisher, A.2
Bautista, D.M.3
McKemy, D.D.4
-
45
-
-
37549037499
-
Insights into the roles of conserved and divergent residues in the ankyrin repeats of TRPV ion channels
-
Phelps CB, Procko E, Lishko PV, Wang RR, Gaudet R (2007) Insights into the roles of conserved and divergent residues in the ankyrin repeats of TRPV ion channels. Channels (Austin) 1:148-151.
-
(2007)
Channels (Austin)
, vol.1
, pp. 148-151
-
-
Phelps, C.B.1
Procko, E.2
Lishko, P.V.3
Wang, R.R.4
Gaudet, R.5
-
46
-
-
0032169804
-
The cloned capsaicin receptor integrates multiple pain-producing stimuli
-
DOI 10.1016/S0896-6273(00)80564-4
-
Tominaga M, et al. (1998) The cloned capsaicin receptor integrates multiple pain-producing stimuli. Neuron 21:531-543. (Pubitemid 28475505)
-
(1998)
Neuron
, vol.21
, Issue.3
, pp. 531-543
-
-
Tominaga, M.1
Caterina, M.J.2
Malmberg, A.B.3
Rosen, T.A.4
Gilbert, H.5
Skinner, K.6
Raumann, B.E.7
Basbaum, A.I.8
Julius, D.9
-
48
-
-
0031697975
-
Temperature dependence of voltage-gated H+ currents in human neutrophils, rat alveolar epithelial cells, and mammalian phagocytes
-
DeCoursey TE, Cherny VV (1998) Temperature dependence of voltage-gated H+ currents in human neutrophils, rat alveolar epithelial cells, and mammalian phagocytes. J Gen Physiol 112:503-522.
-
(1998)
J Gen Physiol
, vol.112
, pp. 503-522
-
-
DeCoursey, T.E.1
Cherny, V.V.2
|