Optimization of poly(β-L-malic acid) production using aureobasidium pullulans by response surface methodology

Applied Mechanics and Materials

Volumn 108, Issue , 2012, Pages 121-126

  Qiao, Changsheng ^a   Zhong, Kun ^a   Hao, Huaxuan ^a   Jia, Yuanyuan ^a  

^a TIANJIN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Aureobasidium pullulans; Optimization; Poly( L malic acid); Response surface methodology

Indexed keywords

AGITATION SPEED; AUREOBASIDIUM PULLULANS; CORN STEEP LIQUOR; INCUBATION TIME; L-MALIC ACID; LIQUID LOADING; OPTIMUM CONDITIONS; PLACKETT-BURMAN; RESPONSE SURFACE METHODOLOGY; SHAKING FLASKS; SUCCINIC ACIDS;

BOTTLES; CALCIUM CARBONATE; GLUCOSE; LIQUIDS; MECHANICAL ENGINEERING; OPTIMIZATION; SURFACE PROPERTIES;

SURFACES;

EID: 81755166578     PISSN: 16609336     EISSN: 16627482     Source Type: Book Series    
DOI: 10.4028/www.scientific.net/AMM.108.121     Document Type: Conference Paper

References (8)

1. Phillppe Guerin, Michel Vert, Christian Braund, et al. Drug carriers: Optically Active Poly (β- malic acid) [J]. Polymer Bulletin, 1985, 14(2):187~192. (Pubitemid 15586293)
2. Osanai, S; Nakamura, K. Effects of complexation between liposome and poly (malic acid) on aggregation and leakage behaviour [J]. Biomaterials, 2000, 21(9):867~876. (Pubitemid 30114327)
3. José A. Portilla-Arias, Montserrat García-Alvarez, Antxon Martínez de Ilarduya, et al. Synthesis, Degradability, and Drug Releasing Properties of Methyl Esters of Fungal Poly(β-Lmalic acid) [J].Macromolecular Bioscience, 2008, 8: 540~550.
4. Wei Wang, Yuan Liu, Jun Wang, et al. A Novel Copolymer Poly(Lactide-co-b-Malic Acid) with Extended Carboxyl Arms Offering Better Cell Affinity and Hemacompatibility for Blood Vessel Engineering [J].TISSUE ENGINEERING: Part A, 2009, 15(1):65~73.
5. Jeanbat-Mimaud, V, Barbaud, C, Caruelle, P, et al. Bioactive functionalized polymer of malic acid for bone repair and muscle regeneration [J].Journal of Biomaterials Science-Polymer Edition, 2000, 11(9): 979~991.
6. Sandrine Cammas, Marie-Maud Bear, Laurence Moine, etal. Polymers of malic acid and 3- alky-lmalic acid as synthetic PHAs in the design of biocompatible hydrolysable devices.Int [J].Biological Macromolecules, 1999, 25(1-3):273-282. (Pubitemid 29302007)
7. Montgomeryd C. Design and Analysis of Experiments [M]. 3nd. NewYork: John Wiley & Sons, 1991.
8. Ooijkaasl P, Wilkinson E C, Tramper J.Medium Optimization for Spore Production of Coniothyrium Minitans Using Statistically Based Experimental Designs [J].Biotechnology and Bioengineering, 1999, 64(1):92-100. (Pubitemid 29252316)