Adipocytes enhance the proliferation of human leiomyoma cells via TNF-α proinflammatory cytokine

Reproductive Sciences

Volumn 18, Issue 12, 2011, Pages 1186-1192

  Nair, Sangeeta ^a   Al Hendy, Ayman ^a  

^a MEHARRY MEDICAL COLLEGE   (United States)

Author keywords

adipokines; coculture; obesity; uterine leiomyoma

Indexed keywords

CYCLIN D1; CYCLINE; NEUTRALIZING ANTIBODY; PROTEIN BCL 2; TUMOR NECROSIS FACTOR ALPHA;

ADIPOCYTE; APOPTOSIS; ARTICLE; CELL PROLIFERATION; COCULTURE; CONTROLLED STUDY; CULTURE MEDIUM; DISEASE COURSE; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR CELL CULTURE; UPREGULATION; UTERUS MYOMA; WESTERN BLOTTING;

ADIPOCYTES; ANTIBODIES, NEUTRALIZING; BLOTTING, WESTERN; CELL LINE, TUMOR; CELL PROLIFERATION; COCULTURE TECHNIQUES; CULTURE MEDIA, CONDITIONED; CYCLIN D1; FEMALE; HUMANS; LEIOMYOMA; PARACRINE COMMUNICATION; PROLIFERATING CELL NUCLEAR ANTIGEN; PROTO-ONCOGENE PROTEINS C-BCL-2; TIME FACTORS; TUMOR NECROSIS FACTOR-ALPHA; UTERINE NEOPLASMS;

EID: 81555208672     PISSN: 19337191     EISSN: 19337205     Source Type: Journal    
DOI: 10.1177/1933719111408111     Document Type: Article

References (43)

1. Flake GP, Andersen J, Dixon D. Etiology and pathogenesis of uterine leiomyomas: a review. Environ Health Perspect. 2003 ; 111 (8). 1037-1054 (Pubitemid 36826884)
2. Marshall LM, Spiegelman D, Barbieri RL, et al. Variation in the incidence of uterine leiomyoma among premenopausal women by age and race. Obstet Gynecol. 1997 ; 90 (6). 967-973 (Pubitemid 27510139)
3. Othman EE, Al-Hendy A. Molecular genetics and racial disparities of uterine leiomyomas. Best Pract Res Clin Obstet Gynaecol. 2008 ; 22 (4). 589-601 (Pubitemid 351804123)
4. Wise LA, Palmer JR, Stewart EA, Rosenberg L. Age specific incidence rates for self-reported uterine leiomyomata in the Black Women's health study. Obstet Gynecol. 2005 ; 105 (3). 563-568 (Pubitemid 40271223)
5. Schwartz SM. Epidemiology of uterine leiomyoma. Clin Obstet Gynecol. 2001 ; 44 (2). 316-326
6. Sato F, Nishi M, Kudo R, Miyake H. Body fat distribution and uterine leiomyomas. J Epidemiol. 1998 ; 8 (3). 176-180 (Pubitemid 128788427)
7. Shikora SA, Niloff JM, Bistrian BR, Forse RA, Blackburn GL. Relationship between obesity and uterine leiomyomata. Nutrition. 1991 ; 7 (4). 251-255
8. Farinati F, Cardin R, Cassaro M, et al. Helicobacter pylori, inflammation, oxidative damage and gastric cancer: a morphological, biological and molecular pathway. Eur J Cancer Prev. 2008 ; 17 (3). 195-200 (Pubitemid 351549658)
9. Festa A, D'Agostino Jr R, Williams K, et al. The relation of body fat mass and distribution to markers of chronic inflammation. Int J Obes Relat Metab Disord. 2001 ; 25 (10). 1407-1415 (Pubitemid 32977855)
10. Hotamisligil GS, Arner P, Caro JF, Atkinson RL, Spiegelman BM. Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance. J Clin Invest. 1995 ; 95 (5). 2409-2415
11. Inadera H. The usefulness of circulating adipokine levels for the assessment of obesity-related health problems. Int J Med Sci. 2008 ; 5 (5). 248-262
12. Rajala MW, Scherer PE. Minireview: the adipocyte-at the crossroads of energy homeostasis, inflammation, and atherosclerosis. Endocrinology. 2003 ; 144 (9). 3765-3773 (Pubitemid 37088727)
13. Hotamisligil GS, Shargill NS, Spiegelman BM. Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance. Science. 1993 ; 259 (5091). 87-91 (Pubitemid 23036092)
14. Samad F, Yamamoto K, Pandey M, Loskutoff DJ. Elevated expression of transforming growth factor-beta in adipose tissue from obese mice. Mol Med. 1997 ; 3 (1). 37-48 (Pubitemid 27142523)
15. Fried SK, Bunkin DA, Greenberg AS. Omental and subcutaneous adipose tissues of obese subjects release interleukin-6: depot difference and regulation by glucocorticoid. J Clin Endocrinol Metab. 1998 ; 83 (3). 847-850 (Pubitemid 28496456)
16. Sartipy P, Loskutoff DJ. Monocyte chemoattractant protein 1 in obesity and insulin resistance. Proc Natl Acad Sci USA. 2003 ; 100 (12). 7265-7270 (Pubitemid 36706427)
17. Kershaw EE, Flier JS. Adipose tissue as an endocrine organ. J Clin Endocrinol Metab. 2004 ; 89 (6). 2548-2556 (Pubitemid 38766330)
18. Dandona P, Weinstock R, Thusu K, Abdel-rahman E, Aljada A, Wadden T. Tumor necrosis factor-alpha in sera of obese patients: fall with weight loss. J Clin Endocrinol Metab. 1998 ; 83 (8). 2907-2910 (Pubitemid 28493796)
19. Suganami T, Nishida J, Ogawa Y. A paracrine loop between adipocytes and macrophages aggravates inflammatory changes: role of free fatty acids and tumor necrosis factor alpha. Arterioscler Thromb Vasc Biol. 2005 ; 25 (10). 2062-2068 (Pubitemid 41416301)
20. Aggarwal BB, Natarajan K. Tumor necrosis factors: developments during the last decade. Eur Cytokine Netw. 1996 ; 7 (2). 93-124 (Pubitemid 26144548)
21. Parker WH. Uterine myomas: management. Fertil Steril. 2007 ; 88 (2). 255-271 (Pubitemid 47212168)
22. Sozen I, Arici A. Interactions of cytokines, growth factors, and the extracellular matrix in the cellular biology of uterine leiomyomata. Fertil Steril. 2002 ; 78 (1). 1-12 (Pubitemid 34722662)
23. Richardson MA, Berg DT, Johnston PA, McClure D, Grinnell BW. Human liposarcoma cell line, SW872, secretes cholesteryl ester transfer protein in response to cholesterol. J Lipid Res. 1996 ; 37 (5). 1162-1166 (Pubitemid 26182348)
24. Izem L, Morton RE. Cholesteryl ester transfer protein biosynthesis and cellular cholesterol homeostasis are tightly interconnected. J Biol Chem. 2001 ; 276 (28). 26534-26541
25. Vassiliou G, Benoist F, Lau P, Kavaslar GN, McPherson R. The low density lipoprotein receptor-related protein contributes to selective uptake of high density lipoprotein cholesteryl esters by SW872 liposarcoma cells and primary human adipocytes. J Biol Chem. 2001 ; 276 (52). 48823-48830
26. Oppenheim JJ, Feldmann M Introduction to the Role of Cytokines in Innate Host Defense and Adaptive Immunity. New York, NY: Academic Press ; 2001: 3-20.
27. Varella-Garcia M, Chen L, Zheng X, Yu L, Dixon D. Karyotypic characteristics of human uterine leiomyoma and myometrial cell lines following telomerase induction. Cancer Genet Cytogenet. 2006 ; 170 (1). 71-75 (Pubitemid 44349014)
28. Frühbeck G. The adipose tissue as a source of vasoactive factors. Curr Med Chem Cardiovasc Hematol Agents. 2004 ; 2 (3). 197-208 (Pubitemid 38864704)
29. Trayhurn P, Wood IS. Adipokines: inflammation and the pleiotropic role of white adipose tissue. Br J Nutr. 2004 ; 92 (3). 347-355 (Pubitemid 40277057)
30. Wang B, Trayhurn P. Acute and prolonged effects of TNF-alpha on the expression and secretion of inflammation-related adipokines by human adipocytes differentiated in culture. Endocrinology. 2006 ; 452 (4). 418-427 (Pubitemid 43962051)
31. Kern PA, Saghizadeh M, Ong JM, Bosch RJ, Deem R, Simsolo RB. The expression of tumor necrosis factor in human adipose tissue. Regulation by obesity, weight loss, and relationship to lipoprotein lipase. J Clin Invest. 1995 ; 95 (5). 2111-2119
32. Maachi M, Piéroni L, Bruckert E, et al. Systemic low-grade inflammation is related to circulating and adipose tissue TNFalpha, leptin and IL-6 levels in obese women. Int J Obes. 2004 ; 28 (8). 993-997 (Pubitemid 38998704)
33. Lukasiak S, Schiller C, Oehlschlaeger P, et al. Proinflammatory cytokines cause FAT10 upregulation in cancers of liver and colon. Oncogene. 2008 ; 27 (46). 6068-6074
34. Wang D, DuBois RN. Pro-inflammatory prostaglandins and progression of colorectal cancer. Cancer Lett. 2008 ; 267 (2). 197-203
35. Ross RK, Pike MC, Vessey MP, Bull D, Yeates D, Casagrande JT. Risk factors for uterine fibroids: reduced risk associated with oral contraceptives. Br Med J(Clin Res Ed). 1986 ; 293 (6543). 359-362 (Pubitemid 16034122)
36. Matsuo H, Kurachi O, Shimomura Y, Samoto T, Maruo T. Molecular bases for the actions of ovarian sex steroids in the regulation of proliferation and apoptosis of human uterine leiomyoma. Oncology. 1999 ; 57 (suppl 2). 49-58
37. Danforth DN, Sgagias MK. Tumour necrosis factor-? modulates oestradiol responsiveness of MCF-7 breast cancer cells in vitro. J Endocrinol. 1993 ; 138 (3). 517-528 (Pubitemid 23343080)
38. Terranova PF, Hunter VJ, Roby KF, Hunt JS. Tumor necrosis factor-? in the female reproductive tract. Proc Soc Exp Biol Med. 1995 ; 209 (4). 325-342
39. Tilg H, Moschen R. Role of adiponectin and PBEF/visfatin as regulators of inflammation: involvement in obesity-associated diseases. Clin Sci. 2008 ; 114 (4). 275-288 (Pubitemid 351294003)
40. Tsigos C, Kyrou I, Chala E, et al. Circulating tumor necrosis factor alpha concentrations are higher in abdominal versus peripheral obesity. Metabolism. 1999 ; 48 (10). 1332-1335 (Pubitemid 29496085)
41. Marfella R, Esposito K, Siniscalchi M, et al. Effect of weight loss on cardiac synchronization and proinflammatory cytokines in premenopausal obese women. Diabetes Care. 2004 ; 27 (1). 47-52 (Pubitemid 38196708)
42. Saile B, Matthes N, El Armouche H, Neubauer K, Ramadori G.. The bcl, NFkappaB and p53/p21WAF1 systems are involved in spontaneous apoptosis and in the anti-apoptotic effect of TGF-beta or TNF-alpha on activated hepatic stellate cells. Eur J Cell Biol. 2001 ; 80 (8). 554-561 (Pubitemid 32821626)
43. Moore AB, Yu L, Swartz CD, et al. Human uterine leiomyoma-derived fibroblasts stimulate uterine leiomyoma cell proliferation and collagen type I production, and activate RTKs and TGF beta receptor signaling in coculture. Cell Commun Signal. 2010 ; 10: 8