Overexpression of PGC-1α increases fatty acid oxidative capacity of human skeletal muscle cells

Biochemistry Research International

Volumn , Issue , 2012, Pages

  Nikolić, Nataša ^a   Rhedin, Magdalena ^b   Rustan, Arild C ^a   Storlien, Len ^c   Thoresen, G Hege ^a   Strömstedt, Maria ^b  

^a UNIVERSITY OF OSLO   (Norway)

^b ASTRAZENECA R AND D   (Sweden)

^c UNIVERSITY OF SYDNEY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 81555203161     PISSN: 20902247     EISSN: 20902255     Source Type: Journal    
DOI: 10.1155/2012/714074     Document Type: Article

References (57)

1. Clapham J. C., Storlien L. H., The fatty acid oxidation pathway as a therapeutic target for insulin resistance Expert Opinion on Therapeutic Targets 2006 10 5 749 757 (Pubitemid 44479982)
2. Puigserver P., Wu Z., Park C. W., A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis Cell 1998 92 6 829 839 (Pubitemid 28155321)
3. Puigserver P., Spiegelman B. M., Peroxisome proliferator-activated receptor- coactivator 1 (PGC-1α ): transcriptional coactivator and metabolic regulator Endocrine Reviews 2003 24 1 78 90 (Pubitemid 36223280)
4. Lin J., Handschin C., Spiegelman B. M., Metabolic control through the PGC-1α family of transcription coactivators Cell Metabolism 2005 1 6 361 370 (Pubitemid 43960626)
5. Gilde A. J., Van Bilsen M., Peroxisome proliferator-activated receptors (PPARS): regulators of gene expression in heart and skeletal muscle Acta Physiologica Scandinavica 2003 178 4 425 434 (Pubitemid 36960434)
6. Herzig S., Long F., Jhala U. S., Hedrick S., Quinn R., Bauer A., Rudolph D., Schutz G., Yoon C., Puigserver P., Spiegelman B., Montminy M., CREB regulates hepatic gluconeogenesis through the coactivator PGC-1α Nature 2001 413 179 183 (Pubitemid 32867880)
7. Rhee J., Inoue Y., Yoon J. C., Puigserver P., Fan M., Gonzalez F. J., Spiegelman B. M., Regulation of hepatic fasting response by PPAR coactivator-1 (PGC-1α): requirement for hepatocyte nuclear factor 4 in gluconeogenesis Proceedings of the National Academy of Sciences of the United States of America 2003 100 7 4012 4017 (Pubitemid 36418148)
8. Lehman J. J., Barger P. M., Kovacs A., Peroxisome proliferator-activated receptor coactivator-1 promotes cardiac mitochondrial biogenesis Journal of Clinical Investigation 2000 106 7 847 856
9. Leone T. C., Lehman J. J., Finck B. N., Schaeffer P. J., Wende A. R., Boudina S., Courtois M., Wozniak D. F., Sambandam N., Bernal-Mizrachi C., Chen Z., Holloszy J. O., Medeiros D. M., Schmidt R. E., Saffitz J. E., Abel E. D., Semenkovich C. F., Kelly D. P., PGC-1α deficiency causes multi-system energy metabolic derangements: muscle dysfunction, abnormal weight control and hepatic steatosis PLoS Biology 2005 3 4
10. Baar K., Wende A. R., Jones T. E., Marison M., Nolte L. A., Chen M., Kelly D. P., Holloszy J. O., Adaptations of skeletal muscle to exercise: rapid increase in the transcriptional coactivator PGC-1α The FASEB Journal 2002 16 14 1879 1886 (Pubitemid 35462607)
11. Goto M., Terada S., Kato M., Katoh M., Yokozeki T., Tabata I., Shimokawa T., CDNA cloning and mRNA analysis of PGC-1α in epitrochlearis muscle in swimming-exercised rats Biochemical and Biophysical Research Communications 2000 274 2 350 354 (Pubitemid 30614322)
12. Terada S., Goto M., Kato M., Effects of low-intensity prolonged exercise on PGC-1α mRNA expression in rat epitrochlearis muscle Biochemical and Biophysical Research Communications 2002 296 2 350 354
13. Pilegaard H., Saltin B., Neufer P. D., Exercise induces transient transcriptional activation of the PGC-1α gene in human skeletal muscle Journal of Physiology 2003 546 3 851 858 (Pubitemid 36204518)
14. Irrcher I., Adhihetty P. J., Sheehan T., PPAR coactivator-1 expression during thyroid hormoneand contractile activity-induced mitochondrial adaptations American Journal of Physiology 2003 284 6 C1669 C1677 (Pubitemid 36583408)
15. Little J. P., Safdar A., Cermak N., Acute endurance exercise increases the nuclear abundance of PGC-1α in trained human skeletal muscle American Journal of Physiology 2010 298 4 R912 R917
16. Lin J., Wu H., Tarr P. T., Zhang C. Y., Wu Z., Boss O., Michael L. F., Puigserver P., Isotani E., Olson E. N., Lowell B. B., Bassel-Duby R., Spiegelman B. M., Transcriptional co-activator PGC-1α drives the formation of slow-twitch muscle fibres Nature 2002 418 6899 797 801
17. Mootha V. K., Handschin C., Arlow D., Xie X., Pierre J. S., Sihag S., Yang W., Altshuler D., Puigserver P., Patterson N., Willy P. J., Schulman I. G., Heyman R. A., Lander E. S., Spiegelman B. M., Err and gabpa/b specify pgc-1 -dependent oxidative phosphorylation gene expression that is altered in diabetic muscle Proceedings of the National Academy of Sciences of the United States of America 2004 101 17 6570 6575 (Pubitemid 38586015)
18. Booth F. W., Thomason D. B., Molecular and cellular adaptation of muscle in response to exercise: perspectives of various models Physiological Reviews 1991 71 2 541 585
19. Handschin C., Chin S., Li P., Liu F., Maratos-Flier E., LeBrasseur N. K., Yan Z., Spiegelman B. M., Skeletal muscle fiber-type switching, exercise intolerance, and myopathy in PGC-1α muscle-specific knock-out animals Journal of Biological Chemistry 2007 282 41 30014 30021 (Pubitemid 350035265)
20. Mortensen O. H., Frandsen L., Schjerling P., PGC-1α and PGC-1α have both similar and distinct effects on myofiber switching toward an oxidative phenotype American Journal of Physiology 2006 291 4 E807 E816 (Pubitemid 44484924)
21. Benton C. R., Holloway G. P., Han X. X., Yoshida Y., Snook L. A., Lally J., Glatz J. F. C., Luiken J. J. F. P., Chabowski A., Bonen A., Increased levels of peroxisome proliferator-activated receptor gamma, coactivator 1 (PGC-1α ) improve lipid utilisation, insulin signalling and glucose transport in skeletal muscle of lean and insulin-resistant obese zucker rats Diabetologia 2010 53 9 2008 2019
22. Benton C. R., Nickerson J. G., Lally J., Han X. X., Holloway G. P., Glatz J. F., Luiken J. J., Graham T. E., Heikkila J. J., Bonen A., Modest PGC-1α overexpression in muscle in vivo is sufficient to increase insulin sensitivity and palmitate oxidation in subsarcolemmal, not intermyofibrillar, mitochondria Journal of Biological Chemistry 2008 283 7 4228 4240
23. Liang H., Balas B., Tantiwong P., Whole body overexpression of PGC-1α has opposite effects on hepatic and muscle insulin sensitivity American Journal of Physiology 2009 296 4 E945 E954
24. Michael L. F., Wu Z., Cheatham R. B., Puigserver P., Adelmant G., Lehman J. J., Kelly D. P., Spiegelman B. M., Restoration of insulin-sensitive glucose transporter (GLUT4) gene expression in muscle cells by the transcriptional coactivator PGC-1α Proceedings of the National Academy of Sciences of the United States of America 2001 98 7 3820 3825 (Pubitemid 32249855)
25. Wang Y. X., Lee C. H., Tiep S., Yu R. T., Ham J., Kang H., Evans R. M., Peroxisome-proliferator-activated receptor activates fat metabolism to prevent obesity Cell 2003 113 2 159 170 (Pubitemid 36514968)
26. Wright D. C., Geiger P. C., Han D. H., Calcium induces increases in peroxisome proliferator-activated receptor coactivator-1 and mitochondrial biogenesis by a pathway leading to p38 mitogen-activated protein kinase activation Journal of Biological Chemistry 2007 282 26 18793 18799 (Pubitemid 47100154)
27. Wang Y. X., Zhang C. L., Yu R. T., Cho H. K., Nelson M. C., Bayuga-Ocampo C. R., Ham J., Kang H., Evans R. M., Regulation of muscle fiber type and running endurance by PPAR PLoS Biology 2004 2 10
28. Luquet S., Lopez-Soriano J., Holst D., Gaudel C., Jehl-Pietri C., Fredenrich A., Grimaldi P. A., Roles of peroxisome proliferator-activated receptor (PPAR) in the control of fatty acid catabolism. A new target for the treatment of metabolic syndrome Biochimie 2004 86 11 833 837 (Pubitemid 39602763)
29. Sarabia V., Lam L., Burdett E., Glucose transport in human skeletal muscle cells in culture. Stimulation by insulin and metformin Journal of Clinical Investigation 1992 90 4 1386 1395
30. Ukropcova B., McNeil M., Sereda O., De Jonge L., Xie H., Bray G. A., Smith S. R., Dynamic changes in fat oxidation in human primary myocytes mirror metabolic characteristics of the donor Journal of Clinical Investigation 2005 115 7 1934 1941 (Pubitemid 40979733)
31. Koves T. R., Li P., An J., Akimoto T., Slentz D., Ilkayeva O., Dohm G. L., Yan Z., Newgard C. B., Muoio D. M., Peroxisome proliferator-activated receptor- co-activator 1 -mediated metabolic remodeling of skeletal myocytes mimics exercise training and reverses lipid-induced mitochondrial inefficiency Journal of Biological Chemistry 2005 280 39 33588 33598 (Pubitemid 41397160)
32. Gleyzer N., Vercauteren K., Scarpulla R. C., Control of mitochondrial transcription specificity factors (TFB1M and TFB2M) by nuclear respiratory factors (NRF-1 and NRF-2) and PGC-1α family coactivators Molecular and Cellular Biology 2005 25 4 1354 1366 (Pubitemid 40204913)
33. Kelly D. P., Scarpulla R. C., Transcriptional regulatory circuits controlling mitochondrial biogenesis and function Genes and Development 2004 18 4 357 368 (Pubitemid 38316342)
34. Crew J. R., Falzari K., DiMario J. X., Muscle fiber type specific induction of slow myosin heavy chain 2 gene expression by electrical stimulation Experimental Cell Research 2010 316 6 1039 1049
35. Consitt L. A., Bell J. A., Koves T. R., Muoio D. M., Hulver M. W., Haynie K. R., Dohm G. L., Houmard J. A., Peroxisome proliferator-activated receptor- coactivator-1 overexpression increases lipid oxidation in myocytes from extremely obese individuals Diabetes 2010 59 6 1407 1415
36. Henry R. R., Abrams L., Nikoulina S., Insulin action and glucose metabolism in nondiabetic control and NIDDM subjects. Comparison using human skeletal muscle cell cultures Diabetes 1995 44 8 936 946
37. Gaster M., Beck-Nielsen H., Schroder H. D., Proliferation conditions for human satellite cells. The fractional content of satellite cells Acta Pathologica Microbiologica et Immunologica Scandinavica 2001 109 11 726 734 (Pubitemid 34015454)
38. Skrede S., Wu P., Bremer J., Tetradecylthioacrylic acid, a -oxidation metabolite of tetradecylthiopropionic acid, inhibits fatty acid activation and oxidation in rat World Review of Nutrition and Dietetics 1994 75 30 34
39. Franch J., Aslesen R., Jensen J., Regulation of glycogen synthesis in rat skeletal muscle after glycogen-depleting contractile activity: effects of adrenaline on glycogen synthesis and activation of glycogen synthase and glycogen phosphorylase Biochemical Journal 1999 344, part 1 231 235
40. Sznaidman M. L., Haffner C. D., Maloney P. R., Novel selective small molecule agonists for peroxisome proliferator-activated receptor (PPAR)synthesis and biological activity Bioorganic Medicinal Chemistry Letters 2003 13 9 1517 1521 (Pubitemid 36428550)
41. Ciocoiu C. C., Nikolićc N., Nguyen H. H., Synthesis and dual PPAR / agonist effects of 1,4-disubstituted 1,2,3-triazole analogues of GW 501516 European Journal of Medicinal Chemistry 2010 45 7 3047 3055
42. Alsted T. J., Nybo L., Schweiger M., Adipose triglyceride lipase in human skeletal muscle is upregulated by exercise training American Journal of Physiology 2009 296 3 E445 E453
43. Helge J. W., Biba T. O., Galbo H., Muscle triacylglycerol and hormone-sensitive lipase activity in untrained and trained human muscles European Journal of Applied Physiology 2006 97 5 566 572
44. Jocken J. W., Smit E., Goossens G. H., Essers Y. P. G., Van Baak M. A., Mensink M., Saris W. H., Blaak E. E., Adipose triglyceride lipase (ATGL) expression in human skeletal muscle is type I (oxidative) fiber specific Histochemistry and Cell Biology 2008 129 4 535 538
45. Hood D. A., Irrcher I., Ljubicic V., Coordination of metabolic plasticity in skeletal muscle Journal of Experimental Biology 2006 209 12 2265 2275 (Pubitemid 44065521)
46. Hood D. A., Invited review: contractile activity-induced mitochondrial biogenesis in skeletal muscle Journal of Applied Physiology 2001 90 3 1137 1157 (Pubitemid 32171405)
47. Tarnopolsky M. A., Rennie C. D., Robertshaw H. A., Influence of endurance exercise training and sex on intramyocellular lipid and mitochondrial ultrastructure, substrate use, and mitochondrial enzyme activity American Journal of Physiology 2007 292 3 R1271 R1278 (Pubitemid 46377094)
48. Shadel G. S., Clayton D. A., Mitochondrial transcription initiation. Variation and conservation Journal of Biological Chemistry 1993 268 22 16083 16086 (Pubitemid 23229897)
49. Lee S., Van Remmen H., Csete M., Sod2 overexpression preserves myoblast mitochondrial mass and function, but not muscle mass with aging Aging Cell 2009 8 3 296 310
50. Kleiner S., Nguyen-Tran V., Bare O., PPAR agonism activates fatty acid oxidation via PGC-1α but does not increase mitochondrial gene expression and function Journal of Biological Chemistry 2009 284 28 18624 18633
51. Al-Khalili L., Cartee G. D., Krook A., Rna interference-mediated reduction in GLUT1 inhibits serum-induced glucose transport in primary human skeletal muscle cells Biochemical and Biophysical Research Communications 2003 307 1 127 132 (Pubitemid 36814042)
52. Gaster M., Handberg A., Schurmann A., GLUT11, but not GLUT8 or GLUT12, is expressed in human skeletal muscle in a fibre type-specific pattern Pflugers Archiv European Journal of Physiology 2004 448 1 105 113 (Pubitemid 38657211)
53. Kase E. T., Thoresen G. H., Westerlund S., Liver X receptor antagonist reduces lipid formation and increases glucose metabolism in myotubes from lean, obese and type 2 diabetic individuals Diabetologia 2007 50 10 2171 2180 (Pubitemid 47373846)
54. Kase E. T., Wensaas A. J., Aas V., Hjlund K., Levin K., Hege Thoresen G., Beck-Nielsen H., Rustan A. C., Gaster M., Skeletal muscle lipid accumulation in type 2 diabetes may involve the liver X receptor pathway Diabetes 2005 54 4 1108 1115 (Pubitemid 40446325)
55. Tortorella L. L., Pilch P. F., C 2 C 12 myocytes lack an insulin-responsive vesicular compartment despite dexamethasone-induced GLUT4 expression American Journal of Physiology 2002 283 3 E514 E524 (Pubitemid 35230489)
56. Lillioja S., Young A. A., Culter C. L., Ivy J. L., Abbott W. G., Zawadzki J. K., Yki-Jrvinen H., Christin L., Secomb T. W., Bogardus C., Skeletal muscle capillary density and fiber type are possible determinants of in vivo insulin resistance in man Journal of Clinical Investigation 1987 80 2 415 424
57. Kriketos A. D., Pan D. A., Lillioja S., Cooney G. J., Baur L. A., Milner M. R., Sutton J. R., Jenkins A. B., Bogardus C., Storlien L. H., Interrelationships between muscle morphology, insulin action, and adiposity American Journal of Physiology 1996 270 6 R1332 R1339