Nitric oxide during altitude acclimatization

New England Journal of Medicine

Volumn 365, Issue 20, 2011, Pages 1942-1944

  Janocha, Allison J ^a   Koch, Carl D ^a   Tiso, Mauro ^b   Ponchia, Andrea ^c   Doctor, Allan ^d   Gibbons, Lindsey ^d   Gaston, Benjamin ^e   Beall, Cynthia M ^f   Erzurum, Serpil C ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

^c UNIVERSITY OF PADOVA   (Italy)

^d WASHINGTON UNIVERSITY   (United States)

^e UNIVERSITY OF VIRGINIA   (United States)

^f CASE WESTERN RESERVE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CREATININE; ENDOTHELIN 1; ERYTHROPOIETIN; HEMOGLOBIN; HYPOXIA INDUCIBLE FACTOR; IRON NITROSYLHEMOGLOBIN; NITRATE; NITRIC OXIDE; NITRITE; OXYHEMOGLOBIN; S NITROSOHEMOGLOBIN; UNCLASSIFIED DRUG;

6 MINUTE WALK TEST; ALTITUDE; ALTITUDE ACCLIMATIZATION; ARTERIAL OXYGEN TENSION; BLOOD ANALYSIS; BLOOD LEVEL; BLOOD OXYGENATION; BLOOD SAMPLING; CREATININE URINE LEVEL; FUNCTIONAL ASSESSMENT; HEMOGLOBIN BLOOD LEVEL; HUMAN; HUMAN EXPERIMENT; HYPOXIA; LETTER; NEPAL; OXYGEN SATURATION; PRIORITY JOURNAL; SALIVA LEVEL; SEA LEVEL; URINE LEVEL;

EID: 81455141812     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJMc1107887     Document Type: Letter

References (4)

1. Erzurum SC, Ghosh S, Janocha AJ, et al. Higher blood flow and circulating NO products offset high-altitude hypoxia among Tibetans. Proc Natl Acad Sci U S A 2007;104:17593-8. (Pubitemid 350210880)
2. Datta B, Tufnell-Barrett T, Bleasdale RA, et al. Red blood cell nitric oxide as an endocrine vasoregulator: a potential role in congestive heart failure. Circulation 2004;109:1339-42. (Pubitemid 38387817)
3. Angelo M, Singel DJ, Stamler JS. An S-nitrosothiol (SNO) synthase function of hemoglobin that utilizes nitrite as a substrate. Proc Natl Acad Sci U S A 2006;103:8366-71. (Pubitemid 43838461)
4. Gladwin MT, Grubina R, Doyle MP. The new chemical biology of nitrite reactions with hemoglobin: R-state catalysis, oxidative denitrosylation, and nitrite reductase/anhydrase. Acc Chem Res 2009;42:157-67.