Astrocyte proliferation following stroke in the mouse depends on distance from the infarct

PLoS ONE

Volumn 6, Issue 11, 2011, Pages

  Barreto, George E ^a,b   Sun, Xiaoyun ^a   Xu, Lijun ^a   Giffard, Rona G ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b PONTIFICIA UNIVERSIDAD JAVERIANA   (Colombia)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; BROXURIDINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; ASTROCYTOSIS; CELL COUNT; CELL CYCLE; CELL PROLIFERATION; CONTROLLED STUDY; IMMUNOREACTIVITY; MICROGLIA; MONOCYTE; MORPHOMETRICS; MOUSE; NEUTROPHIL; NONHUMAN; PROTEIN CLEAVAGE; STEREOLOGY; STROKE; ANIMAL; APOPTOSIS; BRAIN INFARCTION; INFLAMMATION; METABOLISM; PATHOLOGY;

ANIMALS; APOPTOSIS; ASTROCYTES; BROMODEOXYURIDINE; CELL PROLIFERATION; CEREBRAL INFARCTION; INFLAMMATION; MICE;

EID: 81455140676     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0027881     Document Type: Article

References (35)

1. Pekny M, Nilsson M, (2005) Astrocyte activation and reactive gliosis. Glia 50: 427-434.
2. Buffo A, Rite I, Tripathi P, Lepier A, Colak D, et al. (2008) Origin and progeny of reactive gliosis: A source of multipotent cells in the injured brain. Proc Natl Acad Sci U S A 105: 3581-3586.
3. Sofroniew MV, (2009) Molecular dissection of reactive astrogliosis and glial scar formation. Trends Neurosci 32: 638-647.
4. Sofroniew MV, Vinters HV, (2010) Astrocytes: biology and pathology. Acta Neuropathol 119: 7-35.
5. Cavanagh JB, (1970) The proliferation of astrocytes around a needle wound in the rat brain. J Anat 106: 471-487.
6. Latov N, Nilaver G, Zimmerman EA, Johnson WG, Silverman AJ, et al. (1979) Fibrillary astrocytes proliferate in response to brain injury: a study combining immunoperoxidase technique for glial fibrillary acidic protein and radioautography of tritiated thymidine. Dev Biol 72: 381-384.
7. Ludwin SK, (1985) Reaction of oligodendrocytes and astrocytes to trauma and implantation. A combined autoradiographic and immunohistochemical study. Lab Invest 52: 20-30.
8. Reier PJ, (1986) Gliosis following CNS injury, the anatomy of astrocytic scars and their influences on axonal elongation. In: Fedoroff S, Vernadakis A, editors. Astrocytes New York Academic Press pp. 263-324.
9. Janeczko K, (1988) The proliferative response of astrocytes to injury in neonatal rat brain. A combined immunocytochemical and autoradiographic study. Brain Res 456: 280-285.
10. Janeczko K, (1989) Spatiotemporal patterns of the astroglial proliferation in rat brain injured at the postmitotic stage of postnatal development: a combined immunocytochemical and autoradiographic study. Brain Res 485: 236-243.
11. Schiffer D, Giordana MT, Cavalla P, Vigliani MC, Attanasio A, (1993) Immunohistochemistry of glial reaction after injury in the rat: double stainings and markers of cell proliferation. Int J Dev Neurosci 11: 269-280.
12. Schiffer D, Giordana MT, Migheli A, Giaccone G, Pezzotta S, et al. (1986) Glial fibrillary acidic protein and vimentin in the experimental glial reaction of the rat brain. Brain Res 374: 110-118.
13. Fernaud-Espinosa I, Nieto-Sampedro M, Bovolenta P, (1993) Differential activation of microglia and astrocytes in aniso- and isomorphic gliotic tissue. Glia 8: 277-291.
14. Hajos F, Gerics B, Turai E, (1993) Astroglial reaction following Wallerian degeneration in the rat visual cortex: proliferation or hypertrophy? Neurobiology (Bp) 1: 123-131.
15. Hatten ME, Liem RK, Shelanski ML, Mason CA, (1991) Astroglia in CNS injury. Glia 4: 233-243.
16. Lindsay RM, (1986) Reactive gliosis. In: Fedoroff S, Vernadakis A, editors. Astrocytes New York Academic Press pp. 231-262.
17. Ridet JL, Malhotra SK, Privat A, Gage FH, (1997) Reactive astrocytes: cellular and molecular cues to biological function. Trends Neurosci 20: 570-577.
18. Vaughn JE, Pease DC, (1970) Electron microscopic studies of wallerian degeneration in rat optic nerves. II. Astrocytes, oligodendrocytes and adventitial cells. J Comp Neurol 140: 207-226.
19. Norenberg MD, (1994) Astrocyte responses to CNS injury. J Neuropathol Exp Neurol 53: 213-220.
20. Liu Y, Namba T, Liu J, Suzuki R, Shioda S, et al. (2010) Glial fibrillary acidic protein-expressing neural progenitors give rise to immature neurons via early intermediate progenitors expressing both glial fibrillary acidic protein and neuronal markers in the adult hippocampus. Neuroscience 166: 241-251.
21. Petito CK, Morgello S, Felix JC, Lesser ML, (1990) The two patterns of reactive astrocytosis in postischemic rat brain. J Cereb Blood Flow Metab 10: 850-859.
22. Cahoy JD, Emery B, Kaushal A, Foo LC, Zamanian JL, et al. (2008) A transcriptome database for astrocytes, neurons, and oligodendrocytes: a new resource for understanding brain development and function. J Neurosci 28: 264-278.
23. Gong S, Zheng C, Doughty ML, Losos K, Didkovsky N, et al. (2003) A gene expression atlas of the central nervous system based on bacterial artificial chromosomes. Nature 425: 917-925.
24. Han RQ, Ouyang YB, Xu L, Agrawal R, Patterson AJ, et al. (2009) Postischemic brain injury is attenuated in mice lacking the beta2-adrenergic receptor. Anesth Analg 108: 280-287.
25. Dingman A, Lee SY, Derugin N, Wendland MF, Vexler ZS, (2006) Aminoguanidine inhibits caspase-3 and calpain activation without affecting microglial activation following neonatal transient cerebral ischemia. Journal of Neurochemistry 96: 1467-1479.
26. Alonso G, (2005) NG2 proteoglycan-expressing cells of the adult rat brain: possible involvement in the formation of glial scar astrocytes following stab wound. Glia 49: 318-338.
27. Myer DJ, Gurkoff GG, Lee SM, Hovda DA, Sofroniew MV, (2006) Essential protective roles of reactive astrocytes in traumatic brain injury. Brain 129: 2761-2772.
28. Popa-Wagner A, Badan I, Walker L, Groppa S, Patrana N, et al. (2007) Accelerated infarct development, cytogenesis and apoptosis following transient cerebral ischemia in aged rats. Acta Neuropathol 113: 277-293.
29. Dziewulska D, (1997) Age-dependent changes in astroglial reactivity in human ischemic stroke. Immunohistochemical study. Folia Neuropathol 35: 99-106.
30. Burns KA, Murphy B, Danzer SC, Kuan CY, (2009) Developmental and post-injury cortical gliogenesis: a genetic fate-mapping study with Nestin-CreER mice. Glia 57: 1115-1129.
31. Dihne M, Block F, Korr H, Topper R, (2001) Time course of glial proliferation and glial apoptosis following excitotoxic CNS injury. Brain Res 902: 178-189.
32. Bushong EA, Martone ME, Jones YZ, Ellisman MH, (2002) Protoplasmic astrocytes in CA1 stratum radiatum occupy separate anatomical domains. J Neurosci 22: 183-192.
33. Ogata K, Kosaka T, (2002) Structural and quantitative analysis of astrocytes in the mouse hippocampus. Neuroscience 113: 221-233.
34. Halassa MM, Fellin T, Takano H, Dong JH, Haydon PG, (2007) Synaptic islands defined by the territory of a single astrocyte. J Neurosci 27: 6473-6477.
35. Broughton BR, Reutens DC, Sobey CG, (2009) Apoptotic mechanisms after cerebral ischemia. Stroke 40: e331-339.